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Bowen disease is not synonymous with intraepidermal squamous cell carcinoma.
Wood BA, Harvey NT, Mesbah Ardakani N, Paton D. Wood BA, et al. Among authors: paton d. Pathology. 2024 Apr;56(3):322-324. doi: 10.1016/j.pathol.2023.10.021. Epub 2024 Jan 23. Pathology. 2024. PMID: 38360444 Review.
In this paper we present historical, clinical, histological and molecular evidence that this is incorrect. The term Bowen disease should be reserved for a subset of intraepidermal squamous cell carcinoma with a distinctive and reproducible morphological pattern, described …
In this paper we present historical, clinical, histological and molecular evidence that this is incorrect. The term Bowen disease sho …
Loteprednol etabonate: a formulation for short-term use in inflammatory flares in dry eye disease.
Paton DM. Paton DM. Drugs Today (Barc). 2022 Feb;58(2):77-84. doi: 10.1358/dot.2022.58.2.3367993. Drugs Today (Barc). 2022. PMID: 35188142
In 2021, Kala Pharmaceuticals launched Eysuvis (loteprednol etabonate ophthalmic suspension) 0.25% in the U.S. for the short-term (up to 2 weeks) treatment of the signs and symptoms of dry eye disease. ...
In 2021, Kala Pharmaceuticals launched Eysuvis (loteprednol etabonate ophthalmic suspension) 0.25% in the U.S. for the short-term (up …
Physiological, biochemical, and anatomical responses of Araucaria araucana seedlings to controlled water restriction.
Papú S, Berli F, Piccoli P, Patón D, Ortega Rodriguez DR, Roig FA. Papú S, et al. Among authors: paton d. Plant Physiol Biochem. 2021 Aug;165:47-56. doi: 10.1016/j.plaphy.2021.05.005. Epub 2021 May 12. Plant Physiol Biochem. 2021. PMID: 34034160
Our findings suggest that under moderate water stress, analogous to short-term droughts, A. araucana seedlings activate physiological mechanisms that allow them to withstand short periods of drought, while more severe water stress and longer droughts can be severely harmfu …
Our findings suggest that under moderate water stress, analogous to short-term droughts, A. araucana seedlings activate physiological …
Professional mental health support seeking in Women of Refugee Background resettled in Australia: An exploratory study of facilitators and barriers.
Hawkes C, Norris K, Joyce J, Paton D. Hawkes C, et al. Among authors: paton d. Health Soc Care Community. 2021 Nov;29(6):e440-e456. doi: 10.1111/hsc.13370. Epub 2021 Apr 2. Health Soc Care Community. 2021. PMID: 33797138
Several factors were identified as being significantly associated with professional mental health support seeking in WoRB resettled in Australia, including age, resettlement location, marital status, prearrival trauma involving violence against women, language barriers and health …
Several factors were identified as being significantly associated with professional mental health support seeking in WoRB resettled in Austr …
Environmental Sampling as a Low-Technology Method for Surveillance of Foot-and-Mouth Disease Virus in an Area of Endemicity.
Colenutt C, Brown E, Nelson N, Wadsworth J, Maud J, Adhikari B, Chapagain Kafle S, Upadhyaya M, Kafle Pandey S, Paton DJ, Sumption K, Gubbins S. Colenutt C, et al. Among authors: paton dj. Appl Environ Microbiol. 2018 Aug 1;84(16):e00686-18. doi: 10.1128/AEM.00686-18. Print 2018 Aug 15. Appl Environ Microbiol. 2018. PMID: 29959244 Free PMC article.
Countries with FMDV face severe trade restrictions, and infections can have long-term effects on the productivity of affected animals. Environmental contamination by the virus in excretions and secretions from infected individuals promotes transmission but also presents an …
Countries with FMDV face severe trade restrictions, and infections can have long-term effects on the productivity of affected animals …
Sebelipase alfa: enzymatic replacement treatment for lysosomal acid lipase deficiency.
Paton DM. Paton DM. Drugs Today (Barc). 2016 May;52(5):287-93. doi: 10.1358/dot.2016.52.5.2488974. Drugs Today (Barc). 2016. PMID: 27376161 Review.
Important unanswered questions remain, such as to what extent treatment with sebelipase alfa alters the long-term cardiovascular and hepatic consequences of this rare recessive genetic disorder. ...
Important unanswered questions remain, such as to what extent treatment with sebelipase alfa alters the long-term cardiovascular and …
PCSK9 inhibitors: monoclonal antibodies for the treatment of hypercholesterolemia.
Paton DM. Paton DM. Drugs Today (Barc). 2016 Mar;52(3):183-92. doi: 10.1358/dot.2016.52.3.2440527. Drugs Today (Barc). 2016. PMID: 27186592 Review.
To date these inhibitors have not caused major adverse effects. However, the results of ongoing long-term randomized clinical trials are needed to determine whether they cause a significant reduction in CVD events including deaths from CVD. ...
To date these inhibitors have not caused major adverse effects. However, the results of ongoing long-term randomized clinical trials …
Viral Dose and Immunosuppression Modulate the Progression of Acute BVDV-1 Infection in Calves: Evidence of Long Term Persistence after Intra-Nasal Infection.
Strong R, La Rocca SA, Paton D, Bensaude E, Sandvik T, Davis L, Turner J, Drew T, Raue R, Vangeel I, Steinbach F. Strong R, et al. Among authors: paton d. PLoS One. 2015 May 8;10(5):e0124689. doi: 10.1371/journal.pone.0124689. eCollection 2015. PLoS One. 2015. PMID: 25955849 Free PMC article.
Finally, a recently developed strand-specific RT-PCR detected negative strand viral RNA, indicative of actively replicating virus, in blood samples from convalescent animals, as late as 85 days post inoculation. This detection of long term replicating virus may indicate th …
Finally, a recently developed strand-specific RT-PCR detected negative strand viral RNA, indicative of actively replicating virus, in blood …
Veterinary and human vaccine evaluation methods.
Knight-Jones TJ, Edmond K, Gubbins S, Paton DJ. Knight-Jones TJ, et al. Among authors: paton dj. Proc Biol Sci. 2014 Apr 16;281(1784):20132839. doi: 10.1098/rspb.2013.2839. Print 2014 Jun 7. Proc Biol Sci. 2014. PMID: 24741009 Free PMC article. Review.
For human vaccines, vaccine efficacy is the proportion of vaccinated individuals protected by the vaccine against a defined outcome under ideal conditions, whereas for veterinary vaccines the term is used for a range of measures of vaccine protection. The evaluation of vac …
For human vaccines, vaccine efficacy is the proportion of vaccinated individuals protected by the vaccine against a defined outcome under id …
Observing micro-evolutionary processes of viral populations at multiple scales.
Orton RJ, Wright CF, Morelli MJ, Juleff N, Thébaud G, Knowles NJ, Valdazo-González B, Paton DJ, King DP, Haydon DT. Orton RJ, et al. Among authors: paton dj. Philos Trans R Soc Lond B Biol Sci. 2013 Feb 4;368(1614):20120203. doi: 10.1098/rstb.2012.0203. Print 2013 Mar 19. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23382425 Free PMC article. Review.
While the current data are limited, rates of nucleotide substitution appear to be faster over individual-to-individual transmission events compared with those observed at a within-individual scale suggesting that viral population bottlenecks between individuals facilitate the fix …
While the current data are limited, rates of nucleotide substitution appear to be faster over individual-to-individual transmission events c …
18 results