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Association between obesity and neurocognitive function in survivors of childhood acute lymphoblastic leukemia treated only with chemotherapy.
Iijima M, Liu W, Panetta JC, Hudson MM, Pui CH, Srivastava DK, Krull KR, Inaba H. Iijima M, et al. Among authors: panetta jc. Cancer. 2021 Sep 1;127(17):3202-3213. doi: 10.1002/cncr.33624. Epub 2021 Apr 29. Cancer. 2021. PMID: 33914910 Free PMC article.
CONCLUSIONS: Overweight/obesity was significantly associated with neurocognitive impairment during long-term follow-up, and this association started early in treatment for ALL. ...
CONCLUSIONS: Overweight/obesity was significantly associated with neurocognitive impairment during long-term follow-up, and this asso …
Psychiatric and Cognitive Aspects of Phenylketonuria: The Limitations of Diet and Promise of New Treatments.
Ashe K, Kelso W, Farrand S, Panetta J, Fazio T, De Jong G, Walterfang M. Ashe K, et al. Among authors: panetta j. Front Psychiatry. 2019 Sep 10;10:561. doi: 10.3389/fpsyt.2019.00561. eCollection 2019. Front Psychiatry. 2019. PMID: 31551819 Free PMC article. Review.
The advent of neonatal heel prick screening has allowed for diagnosis at birth, and the institution of a phenylalanine restricted diet. Dietary treatment, particularly when maintained across neurodevelopment and well into adulthood, has resulted in markedly improved outcom …
The advent of neonatal heel prick screening has allowed for diagnosis at birth, and the institution of a phenylalanine restricted die …
In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.
Sorich MJ, Pottier N, Pei D, Yang W, Kager L, Stocco G, Cheng C, Panetta JC, Pui CH, Relling MV, Cheok MH, Evans WE. Sorich MJ, et al. Among authors: panetta jc. PLoS Med. 2008 Apr 15;5(4):e83. doi: 10.1371/journal.pmed.0050083. PLoS Med. 2008. PMID: 18416598 Free PMC article.

Furthermore, this measure of initial MTX in vivo response and the associated gene expression pattern were predictive of long-term disease-free survival (p < 0.001, p = 0.02). CONCLUSIONS: Together, these data provide new insights into the genomic basis of MTX resistance

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Furthermore, this measure of initial MTX in vivo response and the associated gene expression pattern were predictive of long-term dis …
Effect of high-dose vitamins, coenzyme Q and high-fat diet in paediatric patients with mitochondrial diseases.
Panetta J, Smith LJ, Boneh A. Panetta J, et al. J Inherit Metab Dis. 2004;27(4):487-98. doi: 10.1023/B:BOLI.0000037354.66587.38. J Inherit Metab Dis. 2004. PMID: 15303006
We conclude that high-dose vitamin and cofactor treatment and, where applicable, high-fat diet, are well tolerated and possibly effective in the short term, but ineffective in the longer term....
We conclude that high-dose vitamin and cofactor treatment and, where applicable, high-fat diet, are well tolerated and possibly effective in …
Modeling immunotherapy of the tumor-immune interaction.
Kirschner D, Panetta JC. Kirschner D, et al. Among authors: panetta jc. J Math Biol. 1998 Sep;37(3):235-52. doi: 10.1007/s002850050127. J Math Biol. 1998. PMID: 9785481 Free article.
These efforts are able to explain both short tumor oscillations in tumor sizes as well as long-term tumor relapse. We then explore the effects of adoptive cellular immunotherapy on the model and describe under what circumstances the tumor can be eliminated....
These efforts are able to explain both short tumor oscillations in tumor sizes as well as long-term tumor relapse. We then explore th …