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Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency.
Williams CJ, Chu A, Jefferson WN, Casero D, Sudhakar D, Khurana N, Hogue CP, Aryasomayajula C, Patel P, Sullivan P, Padilla-Banks E, Mohandessi S, Janzen C, Wadehra M. Williams CJ, et al. Among authors: padilla banks e. J Pathol. 2017 Jun;242(2):246-259. doi: 10.1002/path.4893. Epub 2017 May 3. J Pathol. 2017. PMID: 28295343 Free PMC article.
To determine if these results translated to human pregnancy, placentas from normal, term deliveries or those complicated by placental insufficiency resulting in intrauterine growth restriction (IUGR) were stained for EMP2. ...
To determine if these results translated to human pregnancy, placentas from normal, term deliveries or those complicated by placental …
Prenatal exposure to bisphenol a at environmentally relevant doses adversely affects the murine female reproductive tract later in life.
Newbold RR, Jefferson WN, Padilla-Banks E. Newbold RR, et al. Among authors: padilla banks e. Environ Health Perspect. 2009 Jun;117(6):879-85. doi: 10.1289/ehp.0800045. Epub 2009 Jan 15. Environ Health Perspect. 2009. PMID: 19590677 Free PMC article.
OBJECTIVES: In this study we investigated whether prenatal BPA causes long-term adverse effects in female reproductive tissues in an experimental animal model previously shown useful in studying effects of prenatal DES. ...We did not observe these lesions in controls. CONC …
OBJECTIVES: In this study we investigated whether prenatal BPA causes long-term adverse effects in female reproductive tissues in an …
Effects of endocrine disruptors on obesity.
Newbold RR, Padilla-Banks E, Jefferson WN, Heindel JJ. Newbold RR, et al. Among authors: padilla banks e. Int J Androl. 2008 Apr;31(2):201-8. doi: 10.1111/j.1365-2605.2007.00858.x. Int J Androl. 2008. PMID: 18315718 Review.
Together, these data suggest new targets (i.e. adipocyte differentiation and mechanisms involved in weight homeostasis) of abnormal programming by EDCs, and provide evidence that support the scientific term 'the developmental origins of adult disease'. The emerging idea of …
Together, these data suggest new targets (i.e. adipocyte differentiation and mechanisms involved in weight homeostasis) of abnormal programm …
Long-term adverse effects of neonatal exposure to bisphenol A on the murine female reproductive tract.
Newbold RR, Jefferson WN, Padilla-Banks E. Newbold RR, et al. Among authors: padilla banks e. Reprod Toxicol. 2007 Aug-Sep;24(2):253-8. doi: 10.1016/j.reprotox.2007.07.006. Epub 2007 Jul 27. Reprod Toxicol. 2007. PMID: 17804194 Free PMC article.
Since concern has been mounting regarding the human health and environmental effects of bisphenol A (BPA), a high-production-volume chemical with estrogenic activity used in the synthesis of plastics, we investigated its long-term effects in an experimental animal model th …
Since concern has been mounting regarding the human health and environmental effects of bisphenol A (BPA), a high-production-volume chemical …
Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations.
Newbold RR, Padilla-Banks E, Jefferson WN. Newbold RR, et al. Among authors: padilla banks e. Endocrinology. 2006 Jun;147(6 Suppl):S11-7. doi: 10.1210/en.2005-1164. Epub 2006 May 11. Endocrinology. 2006. PMID: 16690809 Review.
In humans and experimental animals, exposure to DES during critical periods of reproductive tract differentiation permanently alters estrogen target tissues and results in long-term abnormalities such as uterine neoplasia that are not manifested until later in life. ...Tog …
In humans and experimental animals, exposure to DES during critical periods of reproductive tract differentiation permanently alters estroge …
Developmental exposure to diethylstilbestrol (DES) alters uterine response to estrogens in prepubescent mice: low versus high dose effects.
Newbold RR, Jefferson WN, Padilla-Banks E, Haseman J. Newbold RR, et al. Among authors: padilla banks e. Reprod Toxicol. 2004 May;18(3):399-406. doi: 10.1016/j.reprotox.2004.01.007. Reprod Toxicol. 2004. PMID: 15082075
A similar dose-response curve was seen in 4 months old ovariectomized DES-treated mice suggesting the altered response was long-term. These data suggest xenoestrogen exposure during critical developmental windows alters hormone programming so that the uterus responds abnor …
A similar dose-response curve was seen in 4 months old ovariectomized DES-treated mice suggesting the altered response was long-term. …