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Page 1
Cortical responsive neurostimulation in a baboon with genetic generalized epilepsy.
Ákos Szabó C, De La Garza M, Shade R, Papanastassiou AM, Nathanielsz P. Ákos Szabó C, et al. Epilepsy Behav. 2021 Jul;120:107973. doi: 10.1016/j.yebeh.2021.107973. Epub 2021 May 4. Epilepsy Behav. 2021. PMID: 33962250 Free PMC article.
More broadly, this study demonstrates opportunities for evaluating seizure detection as well as chronic therapeutic interventions over long term in the baboon....
More broadly, this study demonstrates opportunities for evaluating seizure detection as well as chronic therapeutic interventions over long …
Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction.
Pereira SP, Tavares LC, Duarte AI, Baldeiras I, Cunha-Oliveira T, Martins JD, Santos MS, Maloyan A, Moreno AJ, Cox LA, Li C, Nathanielsz PW, Nijland MJ, Oliveira PJ. Pereira SP, et al. Clin Sci (Lond). 2021 May 14;135(9):1103-1126. doi: 10.1042/CS20201339. Clin Sci (Lond). 2021. PMID: 33899910 Free PMC article.
To enable human translation, we developed a primate baboon model (Papio spp.) of moderate MNR in which mothers receive 70% of control nutrition during pregnancy, resulting in intrauterine growth restriction (IUGR) offspring and later exhibiting myocardial remodeling and heart fai …
To enable human translation, we developed a primate baboon model (Papio spp.) of moderate MNR in which mothers receive 70% of control nutrit …
Comparative analysis of ACE2 protein expression in rodent, non-human primate, and human respiratory tract at baseline and after injury: A conundrum for COVID-19 pathogenesis.
Soni S, Jiang Y, Tesfaigzi Y, Hornick JL, Çataltepe S. Soni S, et al. PLoS One. 2021 Feb 24;16(2):e0247510. doi: 10.1371/journal.pone.0247510. eCollection 2021. PLoS One. 2021. PMID: 33626084 Free PMC article.
ACE2 expression was detected at very low levels in preterm, but was absent in full-term and adult NHP lung homogenates. This pattern of ACE2 expression contrasted with that of transmembrane protease serine type 2 (TMPRSS2), which was significantly increased in full-term …
ACE2 expression was detected at very low levels in preterm, but was absent in full-term and adult NHP lung homogenates. This pattern …
Papio spp. Colon microbiome and its link to obesity in pregnancy.
Li X, Rensing C, Taylor WL, Costelle C, Brejnrod AD, Ferry RJ Jr, Higgins PB, Folli F, Kottapalli KR, Hubbard GB, Dick EJ Jr, Yooseph S, Nelson KE, Schlabritz-Loutsevitch N. Li X, et al. J Med Primatol. 2018 Dec;47(6):393-401. doi: 10.1111/jmp.12366. Epub 2018 Jul 24. J Med Primatol. 2018. PMID: 30039863 Free PMC article.
MATERIAL AND METHODS: Banked tissues were collected under sterile conditions during necropsy, from three non-obese (nOb) and four obese (Ob) near-term pregnant baboons. Sequences were assigned taxonomy using the Ribosomal Database Project classifier. ...
MATERIAL AND METHODS: Banked tissues were collected under sterile conditions during necropsy, from three non-obese (nOb) and four obese (Ob) …
Nonhuman primate breath volatile organic compounds associate with developmental programming and cardio-metabolic status.
Bishop AC, Libardoni M, Choudary A, Misra B, Lange K, Bernal J, Nijland M, Li C, Olivier M, Nathanielsz PW, Cox LA. Bishop AC, et al. J Breath Res. 2018 May 14;12(3):036016. doi: 10.1088/1752-7163/aaba84. J Breath Res. 2018. PMID: 29593130 Free PMC article.
Offspring of nutrient restricted mothers are intrauterine growth restricted (IUGR) at term. By 3.5 years IUGR baboons showed signs of insulin resistance, indicating a pre-diabetic phenotype, in contrast to healthy CON offspring. ...
Offspring of nutrient restricted mothers are intrauterine growth restricted (IUGR) at term. By 3.5 years IUGR baboons showed signs of …
Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections.
Greenwood EJ, Schmidt F, Kondova I, Niphuis H, Hodara VL, Clissold L, McLay K, Guerra B, Redrobe S, Giavedoni LD, Lanford RE, Murthy KK, Rouet F, Heeney JL. Greenwood EJ, et al. PLoS Pathog. 2015 Sep 11;11(9):e1005146. doi: 10.1371/journal.ppat.1005146. eCollection 2015 Sep. PLoS Pathog. 2015. PMID: 26360709 Free PMC article.
Previously, the natural SIVcpz infection of one chimpanzee, and the experimental infection of six chimpanzees was reported, with limited follow-up. Here, we present a long-term study of these seven animals, with a retrospective re-examination of the early stages of infecti …
Previously, the natural SIVcpz infection of one chimpanzee, and the experimental infection of six chimpanzees was reported, with limited fol …
Contrasted patterns of variation and evolutionary convergence at the antiviral OAS1 gene in old world primates.
Fish I, Boissinot S. Fish I, et al. Immunogenetics. 2015 Sep;67(9):487-99. doi: 10.1007/s00251-015-0855-0. Epub 2015 Jul 10. Immunogenetics. 2015. PMID: 26156123 Free PMC article.
Population genetics analyses in hominoids have revealed interesting evolutionary patterns. In Central African chimpanzee, OAS1 has evolved under long-term balancing selection, resulting in the persistence of polymorphisms since the origin of hominoids, whereas human popula …
Population genetics analyses in hominoids have revealed interesting evolutionary patterns. In Central African chimpanzee, OAS1 has evolved u …
Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation.
Pereira SP, Oliveira PJ, Tavares LC, Moreno AJ, Cox LA, Nathanielsz PW, Nijland MJ. Pereira SP, et al. Am J Physiol Renal Physiol. 2015 Jun 1;308(11):F1217-28. doi: 10.1152/ajprenal.00419.2014. Epub 2015 Mar 11. Am J Physiol Renal Physiol. 2015. PMID: 25761880 Free PMC article.
Early life malnutrition results in structural alterations in the kidney, predisposing offspring to later life renal dysfunction. Kidneys of adults who were growth restricted at birth have substantial variations in nephron endowment. Animal models have indicated renal struc …
Early life malnutrition results in structural alterations in the kidney, predisposing offspring to later life renal dysfunction. Kidneys of …
Peripheral insulin resistance and impaired insulin signaling contribute to abnormal glucose metabolism in preterm baboons.
Blanco CL, McGill-Vargas LL, Gastaldelli A, Seidner SR, McCurnin DC, Leland MM, Anzueto DG, Johnson MC, Liang H, DeFronzo RA, Musi N. Blanco CL, et al. Endocrinology. 2015 Mar;156(3):813-23. doi: 10.1210/en.2014-1757. Epub 2015 Jan 5. Endocrinology. 2015. PMID: 25560831 Free PMC article.
Premature infants develop hyperglycemia shortly after birth, increasing their morbidity and death. Surviving infants have increased incidence of diabetes as young adults. ...Preterm baboons (67% gestation) had reduced peripheral insulin sensitivity shortly after birth …
Premature infants develop hyperglycemia shortly after birth, increasing their morbidity and death. Surviving infants have increased i …
Developmental regulation of key gluconeogenic molecules in nonhuman primates.
McGill-Vargas LL, Johnson-Pais T, Johnson MC, Blanco CL. McGill-Vargas LL, et al. Physiol Rep. 2014 Dec 18;2(12):e12243. doi: 10.14814/phy2.12243. Print 2014 Dec 1. Physiol Rep. 2014. PMID: 25524279 Free PMC article.
Aberrant glucose regulation is common in preterm and full-term neonates leading to short and long-term morbidity/mortality; however, glucose metabolism in this population is understudied. ...Fifteen fetal baboons were delivered at 125 day (d) gestational age (GA), 1 …
Aberrant glucose regulation is common in preterm and full-term neonates leading to short and long-term morbidity/mortality; ho …
45 results