DREADD-mediated amygdala activation is sufficient to induce anxiety-like responses in young nonhuman primates.
Mueller SAL, Oler JA, Roseboom PH, Aggarwal N, Kenwood MM, Riedel MK, Elam VR, Olsen ME, DiFilippo AH, Christian BT, Hu X, Galvan A, Boehm MA, Michaelides M, Kalin NH.
Mueller SAL, et al.
Curr Res Neurobiol. 2023 Oct 5;5:100111. doi: 10.1016/j.crneur.2023.100111. eCollection 2023.
Curr Res Neurobiol. 2023.
PMID: 38020807
Free PMC article.
This effect was again observed approximately 1.9 years following surgery, indicating the long-term functional capacity of DREADD-induced neuronal activation. [(11)C]deschloroclozapine PET imaging demonstrated amygdala hM3Dq-HA specific binding, and immunohistochemistry rev …
This effect was again observed approximately 1.9 years following surgery, indicating the long-term functional capacity of DREADD-indu …