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Page 1
Effect of sulfasalazine on inflammation and endothelial function in patients with established coronary artery disease.
Tabit CE, Holbrook M, Shenouda SM, Dohadwala MM, Widlansky ME, Frame AA, Kim BH, Duess MA, Kluge MA, Levit A, Keaney JF Jr, Vita JA, Hamburg NM. Tabit CE, et al. Vasc Med. 2012 Apr;17(2):101-7. doi: 10.1177/1358863X12440117. Vasc Med. 2012. PMID: 22496207 Free PMC article. Clinical Trial.
However, FMD and digital vasodilator response did not significantly change from baseline with long-term sulfasalazine treatment. Short-term sulfasalazine inhibited NFlB activity; however, long-term treatment was poorly tolerated and did not improve endothelia …
However, FMD and digital vasodilator response did not significantly change from baseline with long-term sulfasalazine treatment. Shor …
Flow-induced arterial remodeling relates to endothelial function in the human forearm.
Vita JA, Holbrook M, Palmisano J, Shenouda SM, Chung WB, Hamburg NM, Eskenazi BR, Joseph L, Shapira OM. Vita JA, et al. Circulation. 2008 Jun 17;117(24):3126-33. doi: 10.1161/CIRCULATIONAHA.108.778472. Epub 2008 Jun 9. Circulation. 2008. PMID: 18541736 Free PMC article.
At 1 week, ulnar artery shear stress was increased by 58% (P<0.001), but it was no longer different from baseline at longer-term follow-up. The contralateral ulnar artery was unaffected, which suggests that these findings were not attributable to the systemic effects of …
At 1 week, ulnar artery shear stress was increased by 58% (P<0.001), but it was no longer different from baseline at longer-term f …
Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers.
Hamburg NM, McMackin CJ, Huang AL, Shenouda SM, Widlansky ME, Schulz E, Gokce N, Ruderman NB, Keaney JF Jr, Vita JA. Hamburg NM, et al. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2650-6. doi: 10.1161/ATVBAHA.107.153288. Epub 2007 Oct 11. Arterioscler Thromb Vasc Biol. 2007. PMID: 17932315 Free PMC article.
Our findings may provide insight into the pathogenesis of vascular disease in sedentary individuals and emphasize that even short-term physical inactivity may have adverse metabolic and vascular consequences....
Our findings may provide insight into the pathogenesis of vascular disease in sedentary individuals and emphasize that even short-term …