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Long-term microfluidic tracking of coccoid cyanobacterial cells reveals robust control of division timing.
Yu FB, Willis L, Chau RM, Zambon A, Horowitz M, Bhaya D, Huang KC, Quake SR. Yu FB, et al. BMC Biol. 2017 Feb 14;15(1):11. doi: 10.1186/s12915-016-0344-4. BMC Biol. 2017. PMID: 28196492 Free PMC article.
Synechocystis sp. cells are small and divide slowly, requiring long-term experiments to track single cells. Thus, the cumulative effects of drift over long periods can cause difficulties in monitoring and quantifying cell growth and division dynamics. ...Generation times w …
Synechocystis sp. cells are small and divide slowly, requiring long-term experiments to track single cells. Thus, the cumulative effe …
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.
Koechlein CS, Harris JR, Lee TK, Weeks J, Fox RG, Zimdahl B, Ito T, Blevins A, Jung SH, Chute JP, Chourasia A, Covert MW, Reya T. Koechlein CS, et al. Nat Commun. 2016 Jul 18;7:12169. doi: 10.1038/ncomms12169. Nat Commun. 2016. PMID: 27425143 Free PMC article.
These collectively demonstrate that high-resolution imaging coupled with computational analysis can provide new biological insight, and may in the long term enable creation of a dynamic atlas of cells within their native microenvironment....
These collectively demonstrate that high-resolution imaging coupled with computational analysis can provide new biological insight, and may …
Maintenance of motility bias during cyanobacterial phototaxis.
Chau RMW, Ursell T, Wang S, Huang KC, Bhaya D. Chau RMW, et al. Biophys J. 2015 Apr 7;108(7):1623-1632. doi: 10.1016/j.bpj.2015.01.042. Biophys J. 2015. PMID: 25863054 Free PMC article.
We then show that individual cells respond within minutes to changes in light conditions, and that movement directionality is conferred only by the current light directionality, rather than by a long-term memory of previous conditions. Our measurements indicate that motili …
We then show that individual cells respond within minutes to changes in light conditions, and that movement directionality is conferred only …