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Monoalkoxy BODIPYs--a fluorophore class for bioimaging.
Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R. Courtis AM, et al. Bioconjug Chem. 2014 Jun 18;25(6):1043-51. doi: 10.1021/bc400575w. Epub 2014 May 14. Bioconjug Chem. 2014. PMID: 24797834 Free PMC article.
In this report, we present the development of a new class of BODIPY dyes based on an alkoxy-fluoro-boron-dipyrromethene core. These novel fluorescent dyes, which we term MayaFluors, are characterized by good aqueous solubility and favorable in vitro physicochemical propert …
In this report, we present the development of a new class of BODIPY dyes based on an alkoxy-fluoro-boron-dipyrromethene core. These novel fl …
Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ. Fass DM, et al. Neuropharmacology. 2013 Jan;64:81-96. doi: 10.1016/j.neuropharm.2012.06.043. Epub 2012 Jul 4. Neuropharmacology. 2013. PMID: 22771460 Free PMC article.
Long-term memory formation is known to be critically dependent upon de novo gene expression in the brain. As a consequence, pharmacological enhancement of the transcriptional processes mediating long-term memory formation provides a potential therapeutic strategy fo …
Long-term memory formation is known to be critically dependent upon de novo gene expression in the brain. As a consequence, pharmacol …
Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy.
Runnels JM, Carlson AL, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JM, Azab A, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP. Runnels JM, et al. J Biomed Opt. 2011 Jan-Feb;16(1):011006. doi: 10.1117/1.3520571. J Biomed Opt. 2011. PMID: 21280893 Free PMC article.
We describe the use of complementary optical techniques to track human MM cells expressing both bioluminescent and fluorescent reporters in a mouse xenograft model. Long-term tumor growth and response to therapy are monitored using bioluminescence imaging (BLI), while numb …
We describe the use of complementary optical techniques to track human MM cells expressing both bioluminescent and fluorescent reporters in …