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Composition and origin of lung fluid proteome in premature infants and relationship to respiratory outcome.
Ballard PL, Oses-Prieto J, Chapin C, Segal MR, Ballard RA, Burlingame AL. Ballard PL, et al. PLoS One. 2020 Dec 10;15(12):e0243168. doi: 10.1371/journal.pone.0243168. eCollection 2020. PLoS One. 2020. PMID: 33301538 Free PMC article.
Pulmonary morbidity was defined as a need for ventilatory support at term and during the first year. RESULTS: Abundant TA proteins included albumin, hemoglobin, and actin-related proteins. 96 of 137 detected plasma proteins were present in TA (r = 0.69, p<0.00001). ...
Pulmonary morbidity was defined as a need for ventilatory support at term and during the first year. RESULTS: Abundant TA proteins in …
Hypoxia-ischemia modifies postsynaptic GluN2B-containing NMDA receptor complexes in the neonatal mouse brain.
Lu F, Shao G, Wang Y, Guan S, Burlingame AL, Liu X, Liang X, Knox R, Ferriero DM, Jiang X. Lu F, et al. Exp Neurol. 2018 Jan;299(Pt A):65-74. doi: 10.1016/j.expneurol.2017.10.005. Epub 2017 Oct 6. Exp Neurol. 2018. PMID: 28993251 Free PMC article.
The early responses of postsynaptic NMDAR complexes and their related signaling networks may contribute to molecular processes leading to cell survival or death, brain damage and/or neurological disorders in term infants with neonatal encephalopathy....
The early responses of postsynaptic NMDAR complexes and their related signaling networks may contribute to molecular processes leading to ce …
Antiinflammatory Effects of Budesonide in Human Fetal Lung.
Barrette AM, Roberts JK, Chapin C, Egan EA, Segal MR, Oses-Prieto JA, Chand S, Burlingame AL, Ballard PL. Barrette AM, et al. Am J Respir Cell Mol Biol. 2016 Nov;55(5):623-632. doi: 10.1165/rcmb.2016-0068OC. Am J Respir Cell Mol Biol. 2016. PMID: 27281349 Free PMC article.
Lung inflammation in premature infants contributes to the development of bronchopulmonary dysplasia (BPD), a chronic lung disease with long-term sequelae. Pilot studies administering budesonide suspended in surfactant have found reduced BPD without the apparent adverse eff …
Lung inflammation in premature infants contributes to the development of bronchopulmonary dysplasia (BPD), a chronic lung disease with long- …
Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.
Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM. Sos ML, et al. Cell Rep. 2014 Aug 21;8(4):1037-48. doi: 10.1016/j.celrep.2014.07.010. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127139 Free PMC article.
Overall, we show that the signaling plasticity exerted by primary resistant BRAF-mutant cells is achieved by their ability to mimic signaling features of oncogenic RAS, a strategy that we term "oncogene mimicry." This model may guide future strategies for overcoming primar …
Overall, we show that the signaling plasticity exerted by primary resistant BRAF-mutant cells is achieved by their ability to mimic signalin …