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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 2
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2009 5
2010 2
2011 1
2012 6
2013 5
2014 6
2015 4
2016 2
2017 3
2018 1
2019 1
2021 1
2024 0

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34 results

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Page 1
Bioenergetic maladaptation and release of HMGB1 in calcineurin inhibitor-mediated nephrotoxicity.
Zmijewska AA, Zmijewski JW, Becker EJ Jr, Benavides GA, Darley-Usmar V, Mannon RB. Zmijewska AA, et al. Am J Transplant. 2021 Sep;21(9):2964-2977. doi: 10.1111/ajt.16561. Epub 2021 Apr 2. Am J Transplant. 2021. PMID: 33724664 Free PMC article.
Calcineurin inhibitors (CNIs) are potent immunosuppressive agents, universally used following solid organ transplantation to prevent rejection. Although effective, the long-term use of CNIs is associated with nephrotoxicity. The etiology of this adverse effect is complex, …
Calcineurin inhibitors (CNIs) are potent immunosuppressive agents, universally used following solid organ transplantation to prevent rejecti …
Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment.
Butler AA, Johnston DR, Kaur S, Lubin FD. Butler AA, et al. Sci Signal. 2019 Jul 2;12(588):eaaw9277. doi: 10.1126/scisignal.aaw9277. Sci Signal. 2019. PMID: 31266852 Free PMC article.
Histone methylation is critical for the formation and maintenance of long-term memories. Long noncoding RNAs (lncRNAs) are regulators of histone methyltransferases and other chromatin-modifying enzymes (CMEs), thereby epigenetically modifying gene expression. ...These resu …
Histone methylation is critical for the formation and maintenance of long-term memories. Long noncoding RNAs (lncRNAs) are regulators …
Effect of Levodopa-carbidopa Intestinal Gel on Non-motor Symptoms in Patients with Advanced Parkinson's Disease.
Standaert DG, Rodriguez RL, Slevin JT, Lobatz M, Eaton S, Chatamra K, Facheris MF, Hall C, Sail K, Jalundhwala YJ, Benesh J. Standaert DG, et al. Mov Disord Clin Pract. 2017 Nov-Dec;4(6):829-837. doi: 10.1002/mdc3.12526. Epub 2017 Sep 20. Mov Disord Clin Pract. 2017. PMID: 29242809 Free PMC article.
BACKGROUND: Levodopa-carbidopa intestinal gel (LCIG; carbidopa-levodopa enteral suspension in the United States), delivered via percutaneous gastrojejunostomy (PEG-J) and titrated in the inpatient setting, is an established treatment option for advanced Parkinson's disease (PD) p …
BACKGROUND: Levodopa-carbidopa intestinal gel (LCIG; carbidopa-levodopa enteral suspension in the United States), delivered via percutaneous …
Deficits in synaptic function occur at medial perforant path-dentate granule cell synapses prior to Schaffer collateral-CA1 pyramidal cell synapses in the novel TgF344-Alzheimer's Disease Rat Model.
Smith LA, McMahon LL. Smith LA, et al. Neurobiol Dis. 2018 Feb;110:166-179. doi: 10.1016/j.nbd.2017.11.014. Epub 2017 Dec 1. Neurobiol Dis. 2018. PMID: 29199135 Free PMC article.
Here, we investigated the time-course of synaptic changes in basal transmission, paired-pulse ratio, as an indirect measure of presynaptic release probability, long-term potentiation (LTP), and dendritic spine density at two hippocampal synapses in male and ovariectomized …
Here, we investigated the time-course of synaptic changes in basal transmission, paired-pulse ratio, as an indirect measure of presynaptic r …
Myocardial ischemia/reperfusion impairs neurogenesis and hippocampal-dependent learning and memory.
Evonuk KS, Prabhu SD, Young ME, DeSilva TM. Evonuk KS, et al. Brain Behav Immun. 2017 Mar;61:266-273. doi: 10.1016/j.bbi.2016.09.001. Epub 2016 Sep 4. Brain Behav Immun. 2017. PMID: 27600185 Free PMC article.
Therefore, we conclude that following acute myocardial infarction, rapid inflammatory responses negatively affect neurogenesis, which may underlie long-term changes in learning and memory....
Therefore, we conclude that following acute myocardial infarction, rapid inflammatory responses negatively affect neurogenesis, which may un …
Dietary composition affects the development of cognitive deficits in WT and Tg AD model mice.
Kadish I, Kumar A, Beitnere U, Jennings E, McGilberry W, van Groen T. Kadish I, et al. Exp Gerontol. 2016 Dec 15;86:39-49. doi: 10.1016/j.exger.2016.05.003. Epub 2016 May 7. Exp Gerontol. 2016. PMID: 27167583 Free PMC article.
In the current study we examined the effects that different diets high in carbohydrate, protein or fat content, but similar in caloric value, have on the development of cognitive impairment and brain pathology in wild-type and Tg AD model mice. The results demonstrate that long …
In the current study we examined the effects that different diets high in carbohydrate, protein or fat content, but similar in caloric value …
Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus.
Bartley AF, Lucas EK, Brady LJ, Li Q, Hablitz JJ, Cowell RM, Dobrunz LE. Bartley AF, et al. J Neurosci. 2015 Nov 18;35(46):15276-90. doi: 10.1523/JNEUROSCI.1834-15.2015. J Neurosci. 2015. PMID: 26586816 Free PMC article.
Circuit dysfunction in complex brain disorders such as schizophrenia and autism is caused by imbalances between inhibitory and excitatory synaptic transmission (I/E). Short-term plasticity differentially alters responses from excitatory and inhibitory synapses, causing the …
Circuit dysfunction in complex brain disorders such as schizophrenia and autism is caused by imbalances between inhibitory and excitatory sy …
DNA methylation regulates neuronal glutamatergic synaptic scaling.
Meadows JP, Guzman-Karlsson MC, Phillips S, Holleman C, Posey JL, Day JJ, Hablitz JJ, Sweatt JD. Meadows JP, et al. Sci Signal. 2015 Jun 23;8(382):ra61. doi: 10.1126/scisignal.aab0715. Sci Signal. 2015. PMID: 26106219 Free PMC article.
We hypothesize that this type of synaptic plasticity may be critical for long-term memory storage within cortical circuits, a process that may also depend on epigenetic mechanisms, such as covalent chemical modification of DNA. ...
We hypothesize that this type of synaptic plasticity may be critical for long-term memory storage within cortical circuits, a process …
Ghrelin agonist does not foster insulin resistance but improves cognition in an Alzheimer's disease mouse model.
Kunath N, van Groen T, Allison DB, Kumar A, Dozier-Sharpe M, Kadish I. Kunath N, et al. Sci Rep. 2015 Jun 19;5:11452. doi: 10.1038/srep11452. Sci Rep. 2015. PMID: 26090621 Free PMC article.
The ghrelin agonist impaired glucose tolerance immediately after administration but not in the long term. At the same time, the ghrelin agonist improved spatial learning in the mice, raised their activity levels, and reduced their body weight and fat mass. Immunoassay resu …
The ghrelin agonist impaired glucose tolerance immediately after administration but not in the long term. At the same time, the ghrel …
Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.
Yokoi F, Chen HX, Dang MT, Cheetham CC, Campbell SL, Roper SN, Sweatt JD, Li Y. Yokoi F, et al. PLoS One. 2015 Mar 23;10(3):e0120916. doi: 10.1371/journal.pone.0120916. eCollection 2015. PLoS One. 2015. PMID: 25799505 Free PMC article.
Dyt1 deltaGAG heterozygous knock-in (KI) mice, which mimic deltaGAG mutation in the endogenous gene, exhibit motor deficits and deceased frequency of spontaneous excitatory post-synaptic currents (sEPSCs) and normal theta-burst-induced long-term potentiation (LTP) in the h …
Dyt1 deltaGAG heterozygous knock-in (KI) mice, which mimic deltaGAG mutation in the endogenous gene, exhibit motor deficits and deceased fre …
34 results