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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2008 2
2010 4
2011 2
2012 4
2013 9
2014 4
2015 10
2016 7
2017 8
2018 4
2019 4
2020 1
2021 6
2022 2
2023 3
2024 0

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60 results

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Page 1
Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation.
Dhariwala MO, DeRogatis AM, Okoro JN, Weckel A, Tran VM, Habrylo I, Ojewumi OT, Tammen AE, Leech JM, Merana GR, Carale RO, Barrere-Cain R, Hiam-Galvez KJ, Spitzer MH, Scharschmidt TC. Dhariwala MO, et al. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560039. doi: 10.1101/2023.09.29.560039. bioRxiv. 2023. PMID: 37873143 Free PMC article. Preprint.
Thus, a commensal-driven wave of monocytes into neonatal skin critically facilitates long-term immune homeostasis in this prominent barrier tissue....
Thus, a commensal-driven wave of monocytes into neonatal skin critically facilitates long-term immune homeostasis in this prominent b …
Inhibition of galectin-3 post-infarction impedes progressive fibrosis by regulating inflammatory profibrotic cascades.
Wang X, Gaur M, Mounzih K, Rodriguez HJ, Qiu H, Chen M, Yan L, Cooper BA, Narayan S, Derakhshandeh R, Rao P, Han DD, Nabavizadeh P, Springer ML, John CM. Wang X, et al. Cardiovasc Res. 2023 Nov 25;119(15):2536-2549. doi: 10.1093/cvr/cvad116. Cardiovasc Res. 2023. PMID: 37602717
Gal-3C impeded progressive fibrosis post-MI by down-regulating galectin-3-mediated profibrotic signalling cascades including a reduction in endogenous arginase-1 and inducible nitric oxide synthase (iNOS). CONCLUSION: Gal-3C treatment improved long-term cardiac function po …
Gal-3C impeded progressive fibrosis post-MI by down-regulating galectin-3-mediated profibrotic signalling cascades including a reduction in …
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies.
Goodman DB, Azimi CS, Kearns K, Talbot A, Garakani K, Garcia J, Patel N, Hwang B, Lee D, Park E, Vykunta VS, Shy BR, Ye CJ, Eyquem J, Marson A, Bluestone JA, Roybal KT. Goodman DB, et al. Sci Transl Med. 2022 Nov 9;14(670):eabm1463. doi: 10.1126/scitranslmed.abm1463. Epub 2022 Nov 9. Sci Transl Med. 2022. PMID: 36350984 Free PMC article.
Forty CARs with signaling domains derived from a range of immune cell lineages were evaluated in pooled assays for their ability to stimulate critical T cell effector functions during repetitive stimulation that mimics long-term tumor antigen exposure. Several domains were …
Forty CARs with signaling domains derived from a range of immune cell lineages were evaluated in pooled assays for their ability to stimulat …
Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells.
Parent AV, Ashe S, Nair GG, Li ML, Chavez J, Liu JS, Zhong Y, Streeter PR, Hebrok M. Parent AV, et al. Stem Cell Reports. 2022 Apr 12;17(4):979-992. doi: 10.1016/j.stemcr.2022.02.001. Epub 2022 Mar 3. Stem Cell Reports. 2022. PMID: 35245441 Free PMC article.
Although current differentiation methods produce glucose-responsive beta cells, they can also yield populations of undesired endocrine progenitors and other proliferating cell types that might interfere with long-term islet function and safety of transplanted cells. Here, …
Although current differentiation methods produce glucose-responsive beta cells, they can also yield populations of undesired endocrine proge …
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. Neidleman J, et al. Elife. 2021 Oct 12;10:e72619. doi: 10.7554/eLife.72619. Elife. 2021. PMID: 34636722 Free PMC article.
Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naive vaccinees, with phenotypic features suggesting superior long-term persistence and ability to home to the respiratory tract including the nasopharynx. ...
Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naive vaccinees, with phenotypic features sug …
Active surveillance characterizes human intratumoral T cell exhaustion.
You R, Artichoker J, Fries A, Edwards AW, Combes AJ, Reeder GC, Samad B, Krummel MF. You R, et al. J Clin Invest. 2021 Sep 15;131(18):e144353. doi: 10.1172/JCI144353. J Clin Invest. 2021. PMID: 34292884 Free PMC article.
Intratumoral T cells that might otherwise control tumors are often identified in an "exhausted" state, defined by specific epigenetic modifications and upregulation of genes such as CD38, cytotoxic T-lymphocyte-associated protein 4 (CTLA4), and programmed cell death 1 (PD1). Alth …
Intratumoral T cells that might otherwise control tumors are often identified in an "exhausted" state, defined by specific epigenetic modifi …
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR. Neidleman J, et al. bioRxiv [Preprint]. 2021 Jul 29:2021.05.12.443888. doi: 10.1101/2021.05.12.443888. bioRxiv. 2021. PMID: 34013277 Free PMC article. Updated. Preprint.
Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naive vaccinees, with phenotypic features suggesting superior long-term persistence and ability to home to the respiratory tract including the nasopharynx. ...
Spike-specific T cells from convalescent vaccinees differed strikingly from those of infection-naive vaccinees, with phenotypic features sug …
Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight.
Wang Y, Bernard A, Comblain F, Yue X, Paillart C, Zhang S, Reiter JF, Vaisse C. Wang Y, et al. J Clin Invest. 2021 May 3;131(9):e142064. doi: 10.1172/JCI142064. J Clin Invest. 2021. PMID: 33938449 Free PMC article.
The melanocortin 4 receptor (MC4R) plays a critical role in the long-term regulation of energy homeostasis, and mutations in the MC4R are the most common cause of monogenic obesity. ...
The melanocortin 4 receptor (MC4R) plays a critical role in the long-term regulation of energy homeostasis, and mutations in the MC4R …
Longitudinal Evolution of Bone Microarchitecture and Bone Strength in Type 2 Diabetic Postmenopausal Women With and Without History of Fragility Fractures-A 5-Year Follow-Up Study Using High Resolution Peripheral Quantitative Computed Tomography.
Heilmeier U, Joseph GB, Pasco C, Dinh N, Torabi S, Darakananda K, Youm J, Carballido-Gamio J, Burghardt AJ, Link TM, Kazakia GJ. Heilmeier U, et al. Front Endocrinol (Lausanne). 2021 Mar 16;12:599316. doi: 10.3389/fendo.2021.599316. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 33796067 Free PMC article.
CONCLUSION: Our data suggest that despite different baseline levels in cortical porosity, T2D women with and without fractures experienced long-term porosity increases at a rate similar to non-diabetics. However, the annual loss in bone strength was greatest in T2D women w …
CONCLUSION: Our data suggest that despite different baseline levels in cortical porosity, T2D women with and without fractures experienced l …
60 results