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1991 2
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2012 8
2013 5
2024 0

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Page 1
Hypoxia-induced ventilatory responses in conscious mice: gender differences in ventilatory roll-off and facilitation.
Palmer LA, May WJ, deRonde K, Brown-Steinke K, Gaston B, Lewis SJ. Palmer LA, et al. Respir Physiol Neurobiol. 2013 Feb 1;185(3):497-505. doi: 10.1016/j.resp.2012.11.010. Epub 2012 Nov 24. Respir Physiol Neurobiol. 2013. PMID: 23183420 Free PMC article.
Upon return to room-air, relatively sustained increases in these ventilatory parameters (short-term potentiation) were observed. In females, the initial responses to hypoxia were similar to those in males whereas roll-off was greater and post-hypoxia facilitation was small …
Upon return to room-air, relatively sustained increases in these ventilatory parameters (short-term potentiation) were observed. In f …
Ventilatory responses during and following exposure to a hypoxic challenge in conscious mice deficient or null in S-nitrosoglutathione reductase.
Palmer LA, May WJ, deRonde K, Brown-Steinke K, Bates JN, Gaston B, Lewis SJ. Palmer LA, et al. Respir Physiol Neurobiol. 2013 Feb 1;185(3):571-81. doi: 10.1016/j.resp.2012.11.009. Epub 2012 Nov 24. Respir Physiol Neurobiol. 2013. PMID: 23183419 Free PMC article.
Exposure to a hypoxic challenge increases ventilation in wild-type (WT) mice that diminish during the challenge (roll-off) whereas return to room air causes an increase in ventilation (short-term facilitation, STF). Since plasma and tissue levels of ventilatory excitant S- …
Exposure to a hypoxic challenge increases ventilation in wild-type (WT) mice that diminish during the challenge (roll-off) whereas return to …
Pulmonary exacerbations in cystic fibrosis: young children with characteristic signs and symptoms.
Regelmann WE, Schechter MS, Wagener JS, Morgan WJ, Pasta DJ, Elkin EP, Konstan MW; Investigators of the Epidemiologic Study of Cystic Fibrosis. Regelmann WE, et al. Pediatr Pulmonol. 2013 Jul;48(7):649-57. doi: 10.1002/ppul.22658. Epub 2012 Sep 4. Pediatr Pulmonol. 2013. PMID: 22949088 Free PMC article.
The presence of these four characteristic signs and symptoms is useful to define pulmonary exacerbations in young children with CF that respond to antibiotic treatment in the short-term and influence long-term prognosis....
The presence of these four characteristic signs and symptoms is useful to define pulmonary exacerbations in young children with CF that resp …
Oral, inhaled, and intravenous antibiotic choice for treating pulmonary exacerbations in cystic fibrosis.
Wagener JS, Rasouliyan L, VanDevanter DR, Pasta DJ, Regelmann WE, Morgan WJ, Konstan MW; Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis. Wagener JS, et al. Pediatr Pulmonol. 2013 Jul;48(7):666-73. doi: 10.1002/ppul.22652. Epub 2012 Aug 8. Pediatr Pulmonol. 2013. PMID: 22888106 Free PMC article.
METHODS: We used 2003-2005 data from the Epidemiologic Study of Cystic Fibrosis to examine antibiotic treatment and the immediate and long-term lung function change associated with clinician reported PExs. ...
METHODS: We used 2003-2005 data from the Epidemiologic Study of Cystic Fibrosis to examine antibiotic treatment and the immediate and long- …
Cystic fibrosis-niche adaptation of Pseudomonas aeruginosa reduces virulence in multiple infection hosts.
Lorè NI, Cigana C, De Fino I, Riva C, Juhas M, Schwager S, Eberl L, Bragonzi A. Lorè NI, et al. PLoS One. 2012;7(4):e35648. doi: 10.1371/journal.pone.0035648. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22558188 Free PMC article.
P. aeruginosa environmental strains are producing various virulence factors that are required for establishing acute infections in several host organisms; however, the P. aeruginosa phenotypic variants favour long-term persistence in the cystic fibrosis (CF) airways. Wheth …
P. aeruginosa environmental strains are producing various virulence factors that are required for establishing acute infections in several h …
Decade-long bacterial community dynamics in cystic fibrosis airways.
Zhao J, Schloss PD, Kalikin LM, Carmody LA, Foster BK, Petrosino JF, Cavalcoli JD, VanDevanter DR, Murray S, Li JZ, Young VB, LiPuma JJ. Zhao J, et al. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5809-14. doi: 10.1073/pnas.1120577109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451929 Free PMC article.
Antibiotic treatment was associated with pronounced shifts in community structure, but communities showed both short- and long-term resilience after antibiotic perturbation. There was a positive correlation between OTU occurrence and relative abundance, with a small number …
Antibiotic treatment was associated with pronounced shifts in community structure, but communities showed both short- and long-term r …
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, De Boeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW. Clancy JP, et al. Thorax. 2012 Jan;67(1):12-8. doi: 10.1136/thoraxjnl-2011-200393. Epub 2011 Aug 8. Thorax. 2012. PMID: 21825083 Free PMC article. Clinical Trial.
Additional data are needed to determine how improvements detected in CFTR function secondary to VX-809 in the sweat gland relate to those measurable in the respiratory tract and to long-term measures of clinical benefit. CLINICAL TRIAL NUMBER: NCT00865904....
Additional data are needed to determine how improvements detected in CFTR function secondary to VX-809 in the sweat gland relate to those me …
Higher PEEP in patients with acute lung injury: a systematic review and meta-analysis.
Dasenbrook EC, Needham DM, Brower RG, Fan E. Dasenbrook EC, et al. Respir Care. 2011 May;56(5):568-75. doi: 10.4187/respcare.01011. Epub 2011 Jan 27. Respir Care. 2011. PMID: 21276322 Free article. Review.
CONCLUSIONS: In 4 recent studies that used volume-limited or pressure-limited ventilation in ALI/ARDS patients, higher PEEP was not associated with significantly different short-term mortality or barotrauma. This study does not support the routine use of higher PEEP in pat …
CONCLUSIONS: In 4 recent studies that used volume-limited or pressure-limited ventilation in ALI/ARDS patients, higher PEEP was not associat …
Association of socioeconomic status with the use of chronic therapies and healthcare utilization in children with cystic fibrosis.
Schechter MS, McColley SA, Silva S, Haselkorn T, Konstan MW, Wagener JS; Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis; North American Scientific Advisory Group for ESCF. Schechter MS, et al. J Pediatr. 2009 Nov;155(5):634-9.e1-4. doi: 10.1016/j.jpeds.2009.04.059. Epub 2009 Jul 16. J Pediatr. 2009. PMID: 19608199 Free PMC article.
12 results