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71 results

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Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.
Wadhwani SI, Kruse G, Squires J, Ebel N, Gupta N, Campbell K, Hsu E, Zielsdorf S, Vittorio J, Desai DM, Bucuvalas JC, Gottlieb LM, Lai JC. Wadhwani SI, et al. Transplantation. 2024 Apr 1;108(4):940-946. doi: 10.1097/TP.0000000000004835. Epub 2024 Mar 23. Transplantation. 2024. PMID: 37831642
Identifying unmet social risks may enable transplant teams to improve long-term outcomes for at-risk children. However, providers may feel uncomfortable asking about household-level social risks in the posttransplant period because they might make their patients/families u …
Identifying unmet social risks may enable transplant teams to improve long-term outcomes for at-risk children. However, providers may …
Association of state Medicaid expansion policies with pediatric liver transplant outcomes.
Shifman HP, Huang CY, Beck AF, Bucuvalas J, Perito ER, Hsu EK, Ebel NH, Lai JC, Wadhwani SI. Shifman HP, et al. Am J Transplant. 2024 Feb;24(2):239-249. doi: 10.1016/j.ajt.2023.09.017. Epub 2023 Sep 28. Am J Transplant. 2024. PMID: 37776976
Our objective was to characterize the impact of Medicaid expansion policies on long-term graft/patient survival after pediatric liver transplantation. ...
Our objective was to characterize the impact of Medicaid expansion policies on long-term graft/patient survival after pediatric liver …
Self-Assembled Matrigel-Free iPSC-Derived Liver Organoids Demonstrate Wide-Ranging Highly Differentiated Liver Functions.
Weng Y, Han S, Sekyi MT, Su T, Mattis AN, Chang TT. Weng Y, et al. Stem Cells. 2023 Mar 2;41(2):126-139. doi: 10.1093/stmcls/sxac090. Stem Cells. 2023. PMID: 36573434 Free PMC article.
We show that RWVs produce highly functional liver organoids in part by eliminating the need for Matrigel, which has adverse effects on hepatic lineage differentiation. RWV liver organoids sustain durable function over long-term culture and express a range of mature functio …
We show that RWVs produce highly functional liver organoids in part by eliminating the need for Matrigel, which has adverse effects on hepat …
Caregiver perspectives on the everyday medical and social needs of long-term pediatric liver transplant patients.
Wadhwani SI, Barrera AG, Shifman HP, Baker E, Bucuvalas J, Gottlieb LM, Kotagal U, Rhee SJ, Lai JC, Lyles CR. Wadhwani SI, et al. Liver Transpl. 2022 Nov;28(11):1735-1746. doi: 10.1002/lt.26498. Epub 2022 Jun 5. Liver Transpl. 2022. PMID: 35524767 Free PMC article.
Caregiver perspectives should help inform future interventions aimed at improving long-term outcomes for children after liver transplantation....
Caregiver perspectives should help inform future interventions aimed at improving long-term outcomes for children after liver transpl …
Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis.
Cullaro G, Hsu CY, Lai JC. Cullaro G, et al. Hepatology. 2022 Oct;76(4):1069-1078. doi: 10.1002/hep.32497. Epub 2022 Apr 15. Hepatology. 2022. PMID: 35357707 Free PMC article.
We highlight that the sCr CoV was associated with higher waitlist and post-LT mortality-an association independent of baseline sCr, the degree of underlying liver disease, the presence of AKI, or the presence of CKD. CONCLUSION: This study informs the long-term impact of t …
We highlight that the sCr CoV was associated with higher waitlist and post-LT mortality-an association independent of baseline sCr, the degr …
Alpelisib combination treatment as novel targeted therapy against hepatocellular carcinoma.
Xu H, Chen K, Shang R, Chen X, Zhang Y, Song X, Evert M, Zhong S, Li B, Calvisi DF, Chen X. Xu H, et al. Cell Death Dis. 2021 Oct 8;12(10):920. doi: 10.1038/s41419-021-04206-5. Cell Death Dis. 2021. PMID: 34625531 Free PMC article.
Hepatocellular carcinoma (HCC) is the sixth most common primary cancer with an unsatisfactory long-term survival. Gain of function mutations of PIK3CA occur in a subset of human HCC. ...
Hepatocellular carcinoma (HCC) is the sixth most common primary cancer with an unsatisfactory long-term survival. Gain of function mu …
The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.
Xu CQ, Mohamad Y, Kappus MR, Boyarsky B, Ganger DR, Volk ML, Rahimi RS, Duarte-Rojo A, McAdams-DeMarco M, Segev DL, Ladner DP, Verna EC, Grab J, Tincopa M, Dunn MA, Lai JC. Xu CQ, et al. Liver Int. 2021 Oct;41(10):2467-2473. doi: 10.1111/liv.15006. Epub 2021 Jul 14. Liver Int. 2021. PMID: 34219362 Free PMC article.
No interaction between frailty and aetiology on the association with waitlist mortality was found (P > .05 for each interaction term). CONCLUSIONS: Frailty is more common in patients with ALD, NAFLD and 'other' aetiologies. ...
No interaction between frailty and aetiology on the association with waitlist mortality was found (P > .05 for each interaction term …
Retransplantation After Living Donor Liver Transplantation: Data from the Adult to Adult Living Donor Liver Transplantation Study.
Braun HJ, Grab JD, Dodge JL, Syed SM, Roll GR, Schwab MP, Liu IH, Glencer AC, Freise CE, Roberts JP, Ascher NL. Braun HJ, et al. Transplantation. 2021 Jun 1;105(6):1297-1302. doi: 10.1097/TP.0000000000003361. Transplantation. 2021. PMID: 33347261 Free PMC article.
The purpose of this study was to analyze the Adult to Adult Living Donor Liver Transplantation Study (A2ALL) data to report outcomes of re-LT after LDLT, with a focus on long-term survival after re-LT. METHODS: A retrospective review of A2ALL data collected between 1998 an …
The purpose of this study was to analyze the Adult to Adult Living Donor Liver Transplantation Study (A2ALL) data to report outcomes of re-L …
Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α.
Duwaerts CC, Siao K, Soon RK Jr, Her C, Iwawaki T, Kohno K, Mattis AN, Maher JJ. Duwaerts CC, et al. Cell Death Differ. 2021 May;28(5):1455-1465. doi: 10.1038/s41418-020-00671-1. Epub 2020 Nov 20. Cell Death Differ. 2021. PMID: 33219328 Free PMC article.
The protective effect of IRE1alpha deletion persisted even with long-term exposure to fructose. Xbp1(deltahep) mice developed liver fibrosis at 16 weeks, but Xbp1(deltahep);Ire1a(deltahep) mice did not. ...
The protective effect of IRE1alpha deletion persisted even with long-term exposure to fructose. Xbp1(deltahep) mice developed liver f …
71 results