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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2006 1
2008 1
2009 1
2010 2
2011 1
2012 1
2015 5
2016 9
2017 1
2018 1
2019 3
2020 14
2021 13
2022 10
2023 10
2024 2

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66 results

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Page 1
Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial.
Rasouli N, Younes N, Ghosh A, Albu J, Cohen RM, DeFronzo RA, Diaz E, Sayyed Kassem L, Luchsinger JA, McGill JB, Sivitz WI, Tamborlane WV, Utzschneider KM, Kahn SE; GRADE Research Group. Rasouli N, et al. Diabetes Care. 2024 Apr 1;47(4):580-588. doi: 10.2337/dc23-1070. Diabetes Care. 2024. PMID: 38211595 Clinical Trial.
OBJECTIVE: To compare the long-term effects of glucose-lowering medications (insulin glargine U-100, glimepiride, liraglutide, and sitagliptin) when added to metformin on insulin sensitivity and beta-cell function. ...After adjustment for HOMA2-%S to obtain an estimate of …
OBJECTIVE: To compare the long-term effects of glucose-lowering medications (insulin glargine U-100, glimepiride, liraglutide, and si …
Impact of Insulin Sensitivity and β-Cell Function Over Time on Glycemic Outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): Differential Treatment Effects of Dual Therapy.
Utzschneider KM, Younes N, Butera NM, Balasubramanyam A, Bergenstal RM, Barzilay J, DeSouza C, DeFronzo RA, Elasy T, Krakoff J, Kahn SE, Rasouli N, Valencia WM, Sivitz WI; GRADE Research Group. Utzschneider KM, et al. Diabetes Care. 2024 Apr 1;47(4):571-579. doi: 10.2337/dc23-1059. Diabetes Care. 2024. PMID: 38190619 Clinical Trial.
CONCLUSIONS: Insulin sensitivity and beta-cell function affected treatment outcomes irrespective of drug assignment, with greater impact in the sitagliptin group on initial (short-term) HbA1c response in comparison with the glimepiride and liraglutide groups....
CONCLUSIONS: Insulin sensitivity and beta-cell function affected treatment outcomes irrespective of drug assignment, with greater impact in …
Mammary duct luminal epithelium controls adipocyte thermogenic programme.
Patel S, Sparman NZR, Arneson D, Alvarsson A, Santos LC, Duesman SJ, Centonze A, Hathaway E, Ahn IS, Diamante G, Cely I, Cho CH, Talari NK, Rajbhandari AK, Goedeke L, Wang P, Butte AJ, Blanpain C, Chella Krishnan K, Lusis AJ, Stanley SA, Yang X, Rajbhandari P. Patel S, et al. Nature. 2023 Aug;620(7972):192-199. doi: 10.1038/s41586-023-06361-5. Epub 2023 Jul 26. Nature. 2023. PMID: 37495690
Single-cell RNA sequencing shows that glandular luminal epithelium subtypes express transcripts that encode secretory factors controlling adipocyte UCP1 expression under cold conditions. We term these luminal epithelium secretory factors 'mammokines'. Using 3D visualizatio …
Single-cell RNA sequencing shows that glandular luminal epithelium subtypes express transcripts that encode secretory factors controlling ad …
Availability of healthy foods, fruit and vegetable consumption, and cognition among urban older adults.
Hyun J, Katz MJ, Derby CA, Roque N, Muñoz E, Sliwinski MJ, Lovasi GS, Lipton RB. Hyun J, et al. BMC Geriatr. 2023 May 17;23(1):302. doi: 10.1186/s12877-023-04003-z. BMC Geriatr. 2023. PMID: 37198552 Free PMC article.
Cognitive performance was assessed using smartphone-administered cognitive tasks that measured processing speed, short-term memory binding, and spatial working memory performance 6 times a day for 14 days. ...
Cognitive performance was assessed using smartphone-administered cognitive tasks that measured processing speed, short-term memory bi …
Impact of Overnight Glucose on Next-Day Functioning in Adults With Type 1 Diabetes: An Exploratory Intensive Longitudinal Study.
Pyatak EA, Spruijt-Metz D, Schneider S, Hernandez R, Pham LT, Hoogendoorn CJ, Peters AL, Crandall J, Jin H, Lee PJ, Gonzalez JS. Pyatak EA, et al. Diabetes Care. 2023 Jul 1;46(7):1345-1353. doi: 10.2337/dc22-2008. Diabetes Care. 2023. PMID: 36862940
RESEARCH DESIGN AND METHODS: Using dynamic structural equation modeling, we examined whether overnight glucose (coefficient of variation[CV], percent time <70 mg/dL, percent time >250 mg/dL) predicted seven next-day functioning outcomes (mobile cognitive tasks, accelerometr …
RESEARCH DESIGN AND METHODS: Using dynamic structural equation modeling, we examined whether overnight glucose (coefficient of variation[CV] …
The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis.
Liu SM, Ifebi B, Johnson F, Xu A, Ho J, Yang Y, Schwartz G, Jo YH, Chua S Jr. Liu SM, et al. J Clin Invest. 2023 Apr 3;133(7):e164185. doi: 10.1172/JCI164185. J Clin Invest. 2023. PMID: 36787185 Free PMC article.
The improved glucose tolerance and reduced body weight persisted up to 6 weeks after cessation of the DREADD-mediated inhibition, suggesting the presence of a biological switch for glucose homeostasis that is regulated by long-term stability of food availability....
The improved glucose tolerance and reduced body weight persisted up to 6 weeks after cessation of the DREADD-mediated inhibition, suggesting …
Using epigenomics to understand cellular responses to environmental influences in diseases.
Wattacheril JJ, Raj S, Knowles DA, Greally JM. Wattacheril JJ, et al. PLoS Genet. 2023 Jan 19;19(1):e1010567. doi: 10.1371/journal.pgen.1010567. eCollection 2023 Jan. PLoS Genet. 2023. PMID: 36656803 Free PMC article. Review.
As there is biochemical evidence that some epigenetic regulators of transcription can maintain their states long term and through cell division, an epigenetic model encompasses the idea of maintenance of the effect of an exposure long after it is no longer present. ...
As there is biochemical evidence that some epigenetic regulators of transcription can maintain their states long term and through cel …
Elevated insulin growth factor-1 in dentate gyrus induces cognitive deficits in pre-term newborns.
Sharma DR, Cheng B, Jaiswal MK, Zhang X, Kumar A, Parikh N, Singh D, Sheth H, Varghese M, Dobrenis K, Zhang X, Hof PR, Stanton PK, Ballabh P. Sharma DR, et al. Cereb Cortex. 2023 May 9;33(10):6449-6464. doi: 10.1093/cercor/bhac516. Cereb Cortex. 2023. PMID: 36646459 Free PMC article.
Here, we show that prematurity and associated neonatal stress disrupt dentate gyrus (DG) development and induce long-term cognitive deficits and that these effects are mediated by insulin growth factor-1 (IGF1). ...However, the density of glutamatergic synapses, mature den …
Here, we show that prematurity and associated neonatal stress disrupt dentate gyrus (DG) development and induce long-term cognitive d …
Outcomes in diabetic patients treated with SGLT2-Inhibitors with acute myocardial infarction undergoing PCI: The SGLT2-I AMI PROTECT Registry.
Paolisso P, Bergamaschi L, Gragnano F, Gallinoro E, Cesaro A, Sardu C, Mileva N, Foà A, Armillotta M, Sansonetti A, Amicone S, Impellizzeri A, Esposito G, Morici N, Andrea OJ, Casella G, Mauro C, Vassilev D, Galie N, Santulli G, Marfella R, Calabrò P, Pizzi C, Barbato E. Paolisso P, et al. Pharmacol Res. 2023 Jan;187:106597. doi: 10.1016/j.phrs.2022.106597. Epub 2022 Dec 5. Pharmacol Res. 2023. PMID: 36470546 Free PMC article.
AIMS: To investigate in-hospital and long-term prognosis in T2DM patients presenting with acute myocardial infarction (AMI) treated with SGLT2-I versus other oral anti-diabetic agents (non-SGLT2-I users). ...Secondary outcomes included i) in-hospital cardiovascular death, …
AIMS: To investigate in-hospital and long-term prognosis in T2DM patients presenting with acute myocardial infarction (AMI) treated w …
Effectiveness of Goal-Directed and Outcome-Based Financial Incentives for Weight Loss in Primary Care Patients With Obesity Living in Socioeconomically Disadvantaged Neighborhoods: A Randomized Clinical Trial.
Ladapo JA, Orstad SL, Wali S, Wylie-Rosett J, Tseng CH, Chung UYR, Cuevas MA, Hernandez C, Parraga S, Ponce R, Sweat V, Wittleder S, Wallach AB, Shu SB, Goldstein NJ, Jay M. Ladapo JA, et al. JAMA Intern Med. 2023 Jan 1;183(1):61-69. doi: 10.1001/jamainternmed.2022.5618. JAMA Intern Med. 2023. PMID: 36469353 Free PMC article. Clinical Trial.
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, outcome-based and goal-directed financial incentives were similarly effective, and both strategies were more effective than providing resources only for clinically significant weight loss in low-income populations with …
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, outcome-based and goal-directed financial incentives were similarly effective, …
66 results