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Year Number of Results
1997 1
2008 1
2010 2
2012 2
2014 5
2015 5
2016 11
2017 5
2018 3
2019 5
2020 4
2021 4
2022 4
2023 3
2024 1

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48 results

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Page 1
An iron rheostat controls hematopoietic stem cell fate.
Kao YR, Chen J, Kumari R, Ng A, Zintiridou A, Tatiparthy M, Ma Y, Aivalioti MM, Moulik D, Sundaravel S, Sun D, Reisz JA, Grimm J, Martinez-Lopez N, Stransky S, Sidoli S, Steidl U, Singh R, D'Alessandro A, Will B. Kao YR, et al. Cell Stem Cell. 2024 Mar 7;31(3):378-397.e12. doi: 10.1016/j.stem.2024.01.011. Epub 2024 Feb 22. Cell Stem Cell. 2024. PMID: 38402617 Free article.
Mechanisms governing the maintenance of blood-producing hematopoietic stem and multipotent progenitor cells (HSPCs) are incompletely understood, particularly those regulating fate, ensuring long-term maintenance, and preventing aging-associated stem cell dysfunction. ...
Mechanisms governing the maintenance of blood-producing hematopoietic stem and multipotent progenitor cells (HSPCs) are incompletely underst …
Prophylactic effect of chronic immunosuppression in a mouse model of CSF-1 receptor-related leukoencephalopathy.
Chitu V, Biundo F, Oppong-Asare J, Gökhan Ş, Aguilan JT, Dulski J, Wszolek ZK, Sidoli S, Stanley ER. Chitu V, et al. Glia. 2023 Nov;71(11):2664-2678. doi: 10.1002/glia.24446. Epub 2023 Jul 30. Glia. 2023. PMID: 37519044
However, familial studies have identified a few carriers of pathogenic CSF1R mutations that remain asymptomatic even in their seventh decade of life, raising the possibility that the development and severity of disease might be influenced by environmental factors. Here we report …
However, familial studies have identified a few carriers of pathogenic CSF1R mutations that remain asymptomatic even in their seventh decade …
A zebrafish xenotransplant model of anaplastic thyroid cancer to study the tumor microenvironment and innate immune cell interactions in vivo.
Michael C, Di Cristofano A, de Oliveira S. Michael C, et al. bioRxiv [Preprint]. 2023 Jun 2:2023.05.29.541816. doi: 10.1101/2023.05.29.541816. bioRxiv. 2023. PMID: 37398266 Free PMC article. Preprint.
Next, using a PIP-FUCCI reporter to track proliferation in-vivo we observed cells in each phase of the cell cycle. Additionally, we performed long-term non-invasive intravital microscopy over 48 hours to understand cellular dynamics in the tumor microenvironment at the sin …
Next, using a PIP-FUCCI reporter to track proliferation in-vivo we observed cells in each phase of the cell cycle. Additionally, we performe …
Dietary Walnuts Preserve Aspects of Health Span and Alter the Hippocampal Lipidome in Aged High-Fat Diet-Fed Mice.
Novaj A, Engel MG, Wang R, Mao K, Xue X, Amir Y, Atzmon G, Huffman DM. Novaj A, et al. Int J Mol Sci. 2023 Jan 24;24(3):2314. doi: 10.3390/ijms24032314. Int J Mol Sci. 2023. PMID: 36768636 Free PMC article.
Additional assays suggested a beneficial effect on some indicators of health with walnut supplementation, including preservation of exercise capacity and improved short-term working memory, as determined by Y maze (p = 0.02). However, no effect was observed via any diet on …
Additional assays suggested a beneficial effect on some indicators of health with walnut supplementation, including preservation of exercise …
A Proposed Link Between Acute Thymic Involution and Late Adverse Effects of Chemotherapy.
Lagou MK, Anastasiadou DP, Karagiannis GS. Lagou MK, et al. Front Immunol. 2022 Jul 1;13:933547. doi: 10.3389/fimmu.2022.933547. eCollection 2022. Front Immunol. 2022. PMID: 35844592 Free PMC article.
Briefly, the theory suggests that newly emerging tumor cells are mostly eliminated by an effective tissue immunosurveillance, but certain tumor variants may occasionally escape innate and adaptive mechanisms of immunological destruction, entering an equilibrium phase, where immun …
Briefly, the theory suggests that newly emerging tumor cells are mostly eliminated by an effective tissue immunosurveillance, but certain tu …
Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD.
Speranza L, Inglebert Y, De Sanctis C, Wu PY, Kalinowska M, McKinney RA, Francesconi A. Speranza L, et al. J Neurosci. 2022 Mar 2;42(9):1666-1678. doi: 10.1523/JNEUROSCI.1466-21.2022. Epub 2022 Jan 19. J Neurosci. 2022. PMID: 35046120 Free PMC article.
Overall, our results identify spines with Synaptopodin/SA as the locus of mGluR-LTD and underscore the importance of the molecular microanatomy of spines in synaptic plasticity.SIGNIFICANCE STATEMENT Long-term changes in functional synaptic strength are associated with mod …
Overall, our results identify spines with Synaptopodin/SA as the locus of mGluR-LTD and underscore the importance of the molecular microanat …
Impact of COVID-19 Mitigation Measures on Inner-City Female Youth in New York City.
Diaz A, Nucci-Sack A, Colon R, Guillot M, Hollman D, Brunelli M, Burk RD, Schlecht NF. Diaz A, et al. J Adolesc Health. 2022 Feb;70(2):220-227. doi: 10.1016/j.jadohealth.2021.10.015. Epub 2021 Oct 16. J Adolesc Health. 2022. PMID: 34836802 Free PMC article.
CONCLUSIONS: The COVID-19 pandemic had unprecedented negative short-term financial and psychosocial health impacts on inner-city female youth with potential long-term negative impacts....
CONCLUSIONS: The COVID-19 pandemic had unprecedented negative short-term financial and psychosocial health impacts on inner-city fema …
Cancer Incidence in World Trade Center Rescue and Recovery Workers: 14 Years of Follow-Up.
Li J, Yung J, Qiao B, Takemoto E, Goldfarb DG, Zeig-Owens R, Cone JE, Brackbill RM, Farfel MR, Kahn AR, Schymura MJ, Shapiro MZ, Dasaro CR, Todd AC, Kristjansson D, Prezant DJ, Boffetta P, Hall CB. Li J, et al. J Natl Cancer Inst. 2022 Feb 7;114(2):210-219. doi: 10.1093/jnci/djab165. J Natl Cancer Inst. 2022. PMID: 34498043 Free PMC article.
CONCLUSIONS: In the largest cohort of 9/11 rescue and recovery workers ever studied, overall cancer incidence was lower than expected, and intensity of WTC exposure was associated with increased risk for specific cancer sites, demonstrating the value of long-term follow-up …
CONCLUSIONS: In the largest cohort of 9/11 rescue and recovery workers ever studied, overall cancer incidence was lower than expected, and i …
Establishment and long-term culture of mouse mammary stem cell organoids and breast tumor organoids.
Cui J, Guo W. Cui J, et al. STAR Protoc. 2021 May 29;2(2):100577. doi: 10.1016/j.xpro.2021.100577. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34124696 Free PMC article.
These organoids maintain the self-renewal of gland-reconstituting MaSCs and can be used to model tumorigenesis by introducing patient-relevant cancer drivers and mutations. Similar organoid culture can be used for long-term expansion of luminal stem/progenitor cells from n …
These organoids maintain the self-renewal of gland-reconstituting MaSCs and can be used to model tumorigenesis by introducing patient-releva …
Blockade of LAG-3 in PD-L1-Deficient Mice Enhances Clearance of Blood Stage Malaria Independent of Humoral Responses.
Furtado R, Chorro L, Zimmerman N, Guillen E, Spaulding E, Chin SS, Daily JP, Lauvau G. Furtado R, et al. Front Immunol. 2021 Jan 14;11:576743. doi: 10.3389/fimmu.2020.576743. eCollection 2020. Front Immunol. 2021. PMID: 33519801 Free PMC article.
Checkpoint blockade therapies targeting these receptors have been largely validated as promising strategies to restore exhausted T cell functions and clearance of chronic infections and tumors. The inability to develop long-term natural immunity in malaria-infected patient …
Checkpoint blockade therapies targeting these receptors have been largely validated as promising strategies to restore exhausted T cell func …
48 results