Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells.
Csiszar A, Sosnowska D, Tucsek Z, Gautam T, Toth P, Losonczy G, Colman RJ, Weindruch R, Anderson RM, Sonntag WE, Ungvari Z.
Csiszar A, et al.
J Gerontol A Biol Sci Med Sci. 2013 Mar;68(3):235-49. doi: 10.1093/gerona/gls158. Epub 2012 Aug 17.
J Gerontol A Biol Sci Med Sci. 2013.
PMID: 22904098
Free PMC article.
To test the hypothesis that circulating factors triggered by CR regulate endothelial angiogenic capacity, we treated cultured human endothelial cells with sera derived from Macaca mulatta on long-term (over 10 years) CR. Cells treated with sera derived from ad-libitum-fed …
To test the hypothesis that circulating factors triggered by CR regulate endothelial angiogenic capacity, we treated cultured human endothel …