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Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models.
Brain Res. 2008 Oct 27;1237:5-11. doi: 10.1016/j.brainres.2008.08.059. Epub 2008 Sep 3.
Brain Res. 2008.
PMID: 18789905
Free PMC article.
Review.
Choline deficiency, through disturbing methyl metabolism, may alter DNA methylation and thereby influence neural precursor cell proliferation and apoptosis. This results in long term alterations in brain structure and function, specifically memory function. ...
Choline deficiency, through disturbing methyl metabolism, may alter DNA methylation and thereby influence neural precursor cell proliferatio …
Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
Zeisel SH.
Zeisel SH.
IUBMB Life. 2007 Jun;59(6):380-7. doi: 10.1080/15216540701468954.
IUBMB Life. 2007.
PMID: 17613168
Free PMC article.
Review.
Choline is critical during fetal development, when it alters DNA methylation and thereby influences neural precursor cell proliferation and apoptosis. This results in long term alterations in brain structure and function, specifically memory function....
Choline is critical during fetal development, when it alters DNA methylation and thereby influences neural precursor cell proliferation and …
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