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Compensatory mechanisms in higher-educated subjects with Alzheimer's disease: a study of 20 years of cognitive decline.
Amieva H, Mokri H, Le Goff M, Meillon C, Jacqmin-Gadda H, Foubert-Samier A, Orgogozo JM, Stern Y, Dartigues JF. Amieva H, et al. Among authors: orgogozo jm. Brain. 2014 Apr;137(Pt 4):1167-75. doi: 10.1093/brain/awu035. Epub 2014 Feb 27. Brain. 2014. PMID: 24578544
A better knowledge of long-term trajectories of cognitive decline is a central feature of the study of the process leading to Alzheimer's dementia. ...
A better knowledge of long-term trajectories of cognitive decline is a central feature of the study of the process leading to Alzheim …
A simple score to predict survival with dementia in the general population.
Delva F, Pimouguet C, Helmer C, Péres K, Bréchat B, Le Goff M, Jacqmin-Gadda H, Amieva H, Orgogozo JM, Auriacombe S, Berr C, Tzourio C, Barberger-Gateau P, Dartigues JF. Delva F, et al. Among authors: orgogozo jm. Neuroepidemiology. 2013;41(1):20-8. doi: 10.1159/000346497. Epub 2013 Mar 19. Neuroepidemiology. 2013. PMID: 23548733
METHODS: Using the Paquid Study (prospective, population-based, long-term cohort study), we created a prognosis score with incident cases of dementia and validated it in another prospective, population-based, long-term cohort study, the Three City Study. - RESULTS: …
METHODS: Using the Paquid Study (prospective, population-based, long-term cohort study), we created a prognosis score with incident c …
Short- versus long-term prediction of dementia among subjects with low and high educational levels.
Chary E, Amieva H, Pérès K, Orgogozo JM, Dartigues JF, Jacqmin-Gadda H. Chary E, et al. Among authors: orgogozo jm. Alzheimers Dement. 2013 Sep;9(5):562-71. doi: 10.1016/j.jalz.2012.05.2188. Epub 2012 Nov 14. Alzheimers Dement. 2013. PMID: 23159045
BACKGROUND: Using simple measures of cognition and disability in a prospective community-living cohort of normal elderly persons, the main objectives of our study were to distinguish short- and long-term predictors for dementia according to educational level and to propose …
BACKGROUND: Using simple measures of cognition and disability in a prospective community-living cohort of normal elderly persons, the main o …
Assessment of quality of life in stroke patients with hemiplegia.
Laurent K, De Sèze MP, Delleci C, Koleck M, Dehail P, Orgogozo JM, Mazaux JM. Laurent K, et al. Among authors: orgogozo jm. Ann Phys Rehabil Med. 2011 Sep;54(6):376-90. doi: 10.1016/j.rehab.2011.06.002. Epub 2011 Aug 5. Ann Phys Rehabil Med. 2011. PMID: 21855441 Free article. English, French.
Indeed, quality of life and subjective well-being should be taken into account in any assessment of stroke survival. OBJECTIVE: To assess long-term quality of life in stroke patients (compared with healthy controls) and the corresponding determinants and predictive factors …
Indeed, quality of life and subjective well-being should be taken into account in any assessment of stroke survival. OBJECTIVE: To assess lo …
Gender differences in the prodromal signs of dementia: memory complaint and IADL-restriction. a prospective population-based cohort.
Pérès K, Helmer C, Amieva H, Matharan F, Carcaillon L, Jacqmin-Gadda H, Auriacombe S, Orgogozo JM, Barberger-Gateau P, Dartigues JF. Pérès K, et al. Among authors: orgogozo jm. J Alzheimers Dis. 2011;27(1):39-47. doi: 10.3233/JAD-2011-110428. J Alzheimers Dis. 2011. PMID: 21725162
The reverse was observed in females, in whom SMC almost doubled the risk of dementia (1.48 to 2.41), with no association with IADL-restriction (p = 0.74). Finally, we distinguished the risk of dementia at short-term (in the first 5 years), mid-term (between 5 and 10 …
The reverse was observed in females, in whom SMC almost doubled the risk of dementia (1.48 to 2.41), with no association with IADL-restricti …
Safety and tolerability of the rivastigmine patch: results of a 28-week open-label extension.
Grossberg G, Sadowsky C, Fröstl H, Frölich L, Nagel J, Tekin S, Zechner S, Ros J, Orgogozo JM. Grossberg G, et al. Among authors: orgogozo jm. Alzheimer Dis Assoc Disord. 2009 Apr-Jun;23(2):158-64. doi: 10.1097/wad.0b013e31818b1c2c. Alzheimer Dis Assoc Disord. 2009. PMID: 19484917 Clinical Trial.
The primary objective of the open-label extension was to evaluate the long-term safety and tolerability of a transdermal rivastigmine patch up to 1 year, as a novel approach to treatment in Alzheimer disease. ...
The primary objective of the open-label extension was to evaluate the long-term safety and tolerability of a transdermal rivastigmine …
Natural history of decline in instrumental activities of daily living performance over the 10 years preceding the clinical diagnosis of dementia: a prospective population-based study.
Pérès K, Helmer C, Amieva H, Orgogozo JM, Rouch I, Dartigues JF, Barberger-Gateau P. Pérès K, et al. Among authors: orgogozo jm. J Am Geriatr Soc. 2008 Jan;56(1):37-44. doi: 10.1111/j.1532-5415.2007.01499.x. Epub 2007 Nov 20. J Am Geriatr Soc. 2008. PMID: 18028344
In practice, restriction in IADLs may be a simple and useful tool for screening subjects at risk of developing dementia in the long term....
In practice, restriction in IADLs may be a simple and useful tool for screening subjects at risk of developing dementia in the long term …
Predictive value of 6-month decline in ADAS-cog for survival without severe Alzheimer's disease.
Helmer C, Andrieu S, Pérès K, Orgogozo JM, Vellas B, Dartigues JF; REAL.fr Group. Helmer C, et al. Among authors: orgogozo jm. Dement Geriatr Cogn Disord. 2007;23(3):168-74. doi: 10.1159/000098516. Epub 2007 Jan 11. Dement Geriatr Cogn Disord. 2007. PMID: 17215578
CONCLUSION: These results confirm the value of the ADAS-cog scale as a judgement criterion in clinical trials since it is a good surrogate marker of long-term prognosis. The proportion of fast decliners on the ADAS-cog could be a helpful judgement criterion for future tria …
CONCLUSION: These results confirm the value of the ADAS-cog scale as a judgement criterion in clinical trials since it is a good surrogate m …
Restriction in complex activities of daily living in MCI: impact on outcome.
Pérès K, Chrysostome V, Fabrigoule C, Orgogozo JM, Dartigues JF, Barberger-Gateau P. Pérès K, et al. Among authors: orgogozo jm. Neurology. 2006 Aug 8;67(3):461-6. doi: 10.1212/01.wnl.0000228228.70065.f1. Neurology. 2006. PMID: 16894108
Conversely, its exclusion results in inappropriate selection of subjects with a low probability of short-term progression to dementia....
Conversely, its exclusion results in inappropriate selection of subjects with a low probability of short-term progression to dementia …
19 results