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Association between sun exposure habits and disease progression in multiple sclerosis.
Wu J, Olsson T, Alfredsson L, Hedström AK. Wu J, et al. Among authors: olsson t. Eur J Neurol. 2024 Mar 5:e16269. doi: 10.1111/ene.16269. Online ahead of print. Eur J Neurol. 2024. PMID: 38440929
METHODS: Patients from a population-based case-control study were categorized based on sun exposure habits at diagnosis and were followed up to 15 years post-diagnosis through the Swedish MS registry (n = 3314) with regard to changes in Expanded Disability Status Scale (EDSS). Li …
METHODS: Patients from a population-based case-control study were categorized based on sun exposure habits at diagnosis and were followed up …
Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis.
Åkesson J, Hojjati S, Hellberg S, Raffetseder J, Khademi M, Rynkowski R, Kockum I, Altafini C, Lubovac-Pilav Z, Mellergård J, Jenmalm MC, Piehl F, Olsson T, Ernerudh J, Gustafsson M. Åkesson J, et al. Among authors: olsson t. Nat Commun. 2023 Oct 30;14(1):6903. doi: 10.1038/s41467-023-42682-9. Nat Commun. 2023. PMID: 37903821 Free PMC article.
With longitudinally followed discovery and replication cohorts, we identify CSF proteins that consistently predicted both short- and long-term disease progression. Lower levels of neurofilament light chain (NfL) in CSF is superior in predicting the absence of disease activ …
With longitudinally followed discovery and replication cohorts, we identify CSF proteins that consistently predicted both short- and long- …
Influence of oral tobacco versus smoking on multiple sclerosis disease activity and progression.
Wu J, Olsson T, Hillert J, Alfredsson L, Hedström AK. Wu J, et al. Among authors: olsson t. J Neurol Neurosurg Psychiatry. 2023 Aug;94(8):589-596. doi: 10.1136/jnnp-2022-330848. Epub 2023 Mar 31. J Neurol Neurosurg Psychiatry. 2023. PMID: 37001984 Free PMC article.
METHOD: Patients from two population-based case-control studies were categorised based on tobacco exposure at diagnosis and were followed up to 15 years post diagnosis through the Swedish MS registry (n=9089) regarding changes in Expanded Disability Status Scale (EDSS), Multiple …
METHOD: Patients from two population-based case-control studies were categorised based on tobacco exposure at diagnosis and were followed up …
Association between brain volume and disability over time in multiple sclerosis.
Moridi T, Stawiarz L, McKay KA, Ineichen BV, Ouellette R, Ferreira D, Muehlboeck JS, Westman E, Kockum I, Olsson T, Piehl F, Hillert J, Manouchehrinia A, Granberg T. Moridi T, et al. Among authors: olsson t. Mult Scler J Exp Transl Clin. 2022 Dec 18;8(4):20552173221144230. doi: 10.1177/20552173221144230. eCollection 2022 Oct-Dec. Mult Scler J Exp Transl Clin. 2022. PMID: 36570871 Free PMC article.
OBJECTIVES: To investigate which brain and lesion volume metrics show the strongest long-term associations with the expanded disability status scale (EDSS), SDMT, and MSIS-29, and whether MRI-clinical associations vary with age. ...Grey matter volume fractions are stronger …
OBJECTIVES: To investigate which brain and lesion volume metrics show the strongest long-term associations with the expanded disabili …
Long-term Treatment With Ponesimod in Relapsing-Remitting Multiple Sclerosis: Results From Randomized Phase 2b Core and Extension Studies.
Freedman MS, Pozzilli C, Havrdova EK, Lemle A, Burcklen M, Larbalestier A, Hennessy B, Sidorenko T, Vaclavkova A, Olsson T; Ponesimod Phase II Study Group. Freedman MS, et al. Among authors: olsson t. Neurology. 2022 Aug 23;99(8):e762-e774. doi: 10.1212/WNL.0000000000200606. Epub 2022 Jun 6. Neurology. 2022. PMID: 35667837 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the dose-response relationship of 10, 20, and 40 mg ponesimod and long-term efficacy and safety of ponesimod 20 mg using an analysis of combined data from the phase 2 Core and Extension studies in patients with relapsing-remitting multiple sclerosis …
OBJECTIVE: To evaluate the dose-response relationship of 10, 20, and 40 mg ponesimod and long-term efficacy and safety of ponesimod 2 …
A Cluster Randomized Trial of Promoting Alternative Thinking Strategies (PATHS®) With Swedish Preschool Children.
Eninger L, Ferrer-Wreder L, Eichas K, Olsson TM, Hau HG, Allodi MW, Smedler AC, Sedem M, Gull IC, Herkner B. Eninger L, et al. Among authors: olsson tm. Front Psychol. 2021 Jul 13;12:695288. doi: 10.3389/fpsyg.2021.695288. eCollection 2021. Front Psychol. 2021. PMID: 34326800 Free PMC article.
However, there is not so much focus on formal instruction nor manual-based lessons. The purpose of this study was to assess the short-term (pre- to post-test) effects of PATHS in the Swedish preschool setting. ...
However, there is not so much focus on formal instruction nor manual-based lessons. The purpose of this study was to assess the short-ter …
Walking Time Is Associated With Hippocampal Volume in Overweight and Obese Office Workers.
Bergman F, Matsson-Frost T, Jonasson L, Chorell E, Sörlin A, Wennberg P, Öhberg F, Ryberg M, Levine JA, Olsson T, Boraxbekk CJ. Bergman F, et al. Among authors: olsson t. Front Hum Neurosci. 2020 Aug 20;14:307. doi: 10.3389/fnhum.2020.00307. eCollection 2020. Front Hum Neurosci. 2020. PMID: 32973475 Free PMC article.
Objectives: To investigate the long-term effects on cognition and brain function after installing treadmill workstations in offices for 13 months. ...
Objectives: To investigate the long-term effects on cognition and brain function after installing treadmill workstations in offices f …
Long-term safety and efficacy of teriflunomide in patients with relapsing multiple sclerosis: Results from the TOWER extension study.
Miller AE, Olsson TP, Wolinsky JS, Comi G, Kappos L, Hu X, Xu X, Lublin AL, Truffinet P, Chavin J, Delhay JL, Benamor M, Purvis A, Freedman MS; TOWER investigators. Miller AE, et al. Among authors: olsson tp. Mult Scler Relat Disord. 2020 Nov;46:102438. doi: 10.1016/j.msard.2020.102438. Epub 2020 Aug 1. Mult Scler Relat Disord. 2020. PMID: 32911306 Clinical Trial.
BACKGROUND: In the phase 3 TOWER core study (NCT00751881), the efficacy and safety of teriflunomide compared with placebo were demonstrated in patients with relapsing forms of multiple sclerosis (RMS). Here, the long-term safety and efficacy outcomes from the TOWER extensi …
BACKGROUND: In the phase 3 TOWER core study (NCT00751881), the efficacy and safety of teriflunomide compared with placebo were demonstrated …
Excess Morbidity Persists in Patients With Cushing's Disease During Long-term Remission: A Swedish Nationwide Study.
Papakokkinou E, Olsson DS, Chantzichristos D, Dahlqvist P, Segerstedt E, Olsson T, Petersson M, Berinder K, Bensing S, Höybye C, Edén-Engström B, Burman P, Bonelli L, Follin C, Petranek D, Erfurth EM, Wahlberg J, Ekman B, Åkerman AK, Schwarcz E, Bryngelsson IL, Johannsson G, Ragnarsson O. Papakokkinou E, et al. Among authors: olsson t. J Clin Endocrinol Metab. 2020 Aug 1;105(8):dgaa291. doi: 10.1210/clinem/dgaa291. J Clin Endocrinol Metab. 2020. PMID: 32436951
CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. ...SIRs for thromboembolism (4.9; 2.6 to 8.4), stroke (3.1; 1.8 to 4.9), and sep …
CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. O …
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