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Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16.
Pedersen AK, Pfeiffer A, Karemore G, Akimov V, Bekker-Jensen DB, Blagoev B, Francavilla C, Olsen JV. Pedersen AK, et al. Among authors: olsen jv. iScience. 2021 Mar 17;24(4):102321. doi: 10.1016/j.isci.2021.102321. eCollection 2021 Apr 23. iScience. 2021. PMID: 33889818 Free PMC article.
Here, we studied the role of E3 ubiquitin ligases Cbl and Cbl-b in regulation of long-term signaling responses associated with extracellular signal-regulated kinase phosphorylation and neurite outgrowth, a morphological marker of neuroblastoma cell differentiation. ...
Here, we studied the role of E3 ubiquitin ligases Cbl and Cbl-b in regulation of long-term signaling responses associated with extrac …
Modeling the cost of eradicating livestock-associated methicillin-resistant staphylococcus aureus in countries with a high proportion of positive herds.
Olsen JV, Calvo-Artavia FF, Sandøe P, Toft N. Olsen JV, et al. Prev Vet Med. 2018 Oct 1;158:97-105. doi: 10.1016/j.prevetmed.2018.07.010. Epub 2018 Jul 31. Prev Vet Med. 2018. PMID: 30220401
Using conservative assumptions, the total eradication costs were estimated at 1.8 billion, broken down into: planning costs (3%), monitoring and testing (6%), cleaning and disinfection (19%), production gains and losses (33%), net loss from breeding exports (19%) and loss of gene …
Using conservative assumptions, the total eradication costs were estimated at 1.8 billion, broken down into: planning costs (3%), monitoring …
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase.
Hertz EPT, Kruse T, Davey NE, López-Méndez B, Sigurðsson JO, Montoya G, Olsen JV, Nilsson J. Hertz EPT, et al. Among authors: olsen jv. Mol Cell. 2016 Aug 18;63(4):686-695. doi: 10.1016/j.molcel.2016.06.024. Epub 2016 Jul 21. Mol Cell. 2016. PMID: 27453045 Free article.
Here, we report that a conserved surface-exposed pocket on PP2A regulatory B56 subunits binds to a consensus sequence on interacting proteins, which we term the LxxIxE motif. The composition of the motif modulates the affinity for B56, which in turn determines the phosphor …
Here, we report that a conserved surface-exposed pocket on PP2A regulatory B56 subunits binds to a consensus sequence on interacting protein …
Pathogens and host immunity in the ancient human oral cavity.
Warinner C, Rodrigues JF, Vyas R, Trachsel C, Shved N, Grossmann J, Radini A, Hancock Y, Tito RY, Fiddyment S, Speller C, Hendy J, Charlton S, Luder HU, Salazar-García DC, Eppler E, Seiler R, Hansen LH, Castruita JA, Barkow-Oesterreicher S, Teoh KY, Kelstrup CD, Olsen JV, Nanni P, Kawai T, Willerslev E, von Mering C, Lewis CM Jr, Collins MJ, Gilbert MT, Rühli F, Cappellini E. Warinner C, et al. Among authors: olsen jv. Nat Genet. 2014 Apr;46(4):336-44. doi: 10.1038/ng.2906. Epub 2014 Feb 23. Nat Genet. 2014. PMID: 24562188 Free PMC article.
We characterize (i) the ancient oral microbiome in a diseased state, (ii) 40 opportunistic pathogens, (iii) ancient human-associated putative antibiotic resistance genes, (iv) a genome reconstruction of the periodontal pathogen Tannerella forsythia, (v) 239 bacterial and 43 human …
We characterize (i) the ancient oral microbiome in a diseased state, (ii) 40 opportunistic pathogens, (iii) ancient human-associated putativ …
Outcomes after transcatheter closure of patent foramen ovale in patients with paradoxical embolism.
Harms V, Reisman M, Fuller CJ, Spencer MP, Olsen JV, Krabill KA, Gray WA, Jesurum JT. Harms V, et al. Among authors: olsen jv. Am J Cardiol. 2007 May 1;99(9):1312-5. doi: 10.1016/j.amjcard.2006.12.055. Epub 2007 Mar 19. Am J Cardiol. 2007. PMID: 17478164
In conclusion, transcatheter patent foramen ovale closure is associated with a low recurrent stroke rate in long-term follow-up....
In conclusion, transcatheter patent foramen ovale closure is associated with a low recurrent stroke rate in long-term follow-up....