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Impact of renal denervation on quality of life (How does renal denervation contribute to improving hypertension treatment affected by poor medication adherence?).
Okamura K, Shimada H, Imazato K, Sako H, Udo A, Taniguchi K, Morisaki S, Imamura I, Urata H, Arima H, Miura SI. Okamura K, et al. Hypertens Res. 2024 Apr 11. doi: 10.1038/s41440-024-01679-7. Online ahead of print. Hypertens Res. 2024. PMID: 38605140 Review.
Although the treatment of HT aims to improve life prognosis, the use of antihypertensive agents can impair QOL because of adverse effects and lifestyle changes associated with long-term medication use. Consequently, poor adherence to antihypertensive agents is a common pro …
Although the treatment of HT aims to improve life prognosis, the use of antihypertensive agents can impair QOL because of adverse effects an …
Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior.
Komori T, Okamura K, Ikehara M, Yamamuro K, Endo N, Okumura K, Yamauchi T, Ikawa D, Ouji-Sageshima N, Toritsuka M, Takada R, Kayashima Y, Ishida R, Mori Y, Kamikawa K, Noriyama Y, Nishi Y, Ito T, Saito Y, Nishi M, Kishimoto T, Tanaka KF, Hiroi N, Makinodan M. Komori T, et al. Among authors: okamura k. Mol Psychiatry. 2024 Jan 19. doi: 10.1038/s41380-024-02413-y. Online ahead of print. Mol Psychiatry. 2024. PMID: 38243072
Additionally, transgenic mice overexpressing microglial Bdnf-regulated using doxycycline at different time points-underwent behavioral, electrophysiological, and gene expression analyses. In these mice, long-term overexpression of microglial BDNF impaired sociability and e …
Additionally, transgenic mice overexpressing microglial Bdnf-regulated using doxycycline at different time points-underwent behavioral, elec …
Effect of Neuromuscular Electrostimulation With Blood Flow Restriction on Acute Muscle Swelling of the Abductor Hallucis.
Okamura K, Hamaguchi M, Ueno Y, Kida T. Okamura K, et al. J Sport Rehabil. 2023 Dec 28;33(2):121-127. doi: 10.1123/jsr.2023-0140. Print 2024 Feb 1. J Sport Rehabil. 2023. PMID: 38154017 Clinical Trial.
CONCLUSIONS: Since it is possible that the amount of muscle swelling immediately after training correlates with muscle hypertrophy when training is continued, the results of this study suggest that NMES training with BFR is a training method that can be expected to produce planta …
CONCLUSIONS: Since it is possible that the amount of muscle swelling immediately after training correlates with muscle hypertrophy when trai …
The Short- and Long-Term Surgical Results of Consecutive Hepatopancreaticoduodenectomy for Wide-Spread Biliary Malignancy.
Yoshimi Y, Noji T, Okamura K, Tanaka K, Matsui A, Nakanishi Y, Asano T, Nakamura T, Tsuchikawa T, Kawamoto Y, Harada K, Fuyama K, Okada K, Hirano S. Yoshimi Y, et al. Among authors: okamura k. Ann Surg Oncol. 2024 Jan;31(1):90-96. doi: 10.1245/s10434-023-14406-2. Epub 2023 Oct 29. Ann Surg Oncol. 2024. PMID: 37899414
BACKGROUND: Cancer-free resection (R0) is one of the most important factors for the long-term survival of biliary carcinoma. For some patients with widespread invasive cancer located between the hilar and intrapancreatic bile duct, hepatopancreaticoduodenectomy (HPD) is co …
BACKGROUND: Cancer-free resection (R0) is one of the most important factors for the long-term survival of biliary carcinoma. For some …
Brain-derived neurotrophic factor from microglia regulates neuronal development in the medial prefrontal cortex and its associated social behavior.
Makinodan M, Komori T, Okamura K, Ikehara M, Yamamuro K, Endo N, Okumura K, Yamauchi T, Ikawa D, Ouji-Sageshima N, Toritsuka M, Takada R, Kayashima Y, Ishida R, Mori Y, Kamikawa K, Noriyama Y, Nishi Y, Ito T, Saito Y, Nishi M, Kishimoto T, Tanaka K, Hiroi N. Makinodan M, et al. Among authors: okamura k. Res Sq [Preprint]. 2023 Jun 30:rs.3.rs-3094335. doi: 10.21203/rs.3.rs-3094335/v1. Res Sq. 2023. PMID: 37461488 Free PMC article. Updated. Preprint.
Additionally, transgenic mice overexpressing microglia Bdnf-regulated using doxycycline at different time points-underwent behavioral, electrophysiological, and gene expression analyses. In these mice, long-term overexpression of microglia BDNF impaired sociability and exc …
Additionally, transgenic mice overexpressing microglia Bdnf-regulated using doxycycline at different time points-underwent behavioral, elect …
Long-term safety and effectiveness of eculizumab in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder: a 2-year interim analysis of post-marketing surveillance in Japan.
Nakashima I, Nakahara J, Yokote H, Manabe Y, Okamura K, Hasegawa K, Fujihara K. Nakashima I, et al. Among authors: okamura k. Ther Adv Neurol Disord. 2023 Jun 30;16:17562864231181177. doi: 10.1177/17562864231181177. eCollection 2023. Ther Adv Neurol Disord. 2023. PMID: 37441104 Free PMC article.
OBJECTIVES: The objective of the study is to assess the real-world, long-term safety and effectiveness of eculizumab in Japanese patients with AQP4+ NMOSD. ...
OBJECTIVES: The objective of the study is to assess the real-world, long-term safety and effectiveness of eculizumab in Japanese pati …
Effect of systemic inflammatory response on induction chemotherapy followed by chemoradiotherapy for locally advanced pancreatic cancer: an exploratory subgroup analysis on systemic inflammatory response in JCOG1106.
Mizuno N, Ioka T, Ogawa G, Nakamura S, Hiraoka N, Ito Y, Katayama H, Takada R, Kobayashi S, Ikeda M, Miwa H, Okano N, Kuramochi H, Sekimoto M, Okusaka T, Ozaka M, Todaka A, Gotoh K, Tobimatsu K, Yamaguchi H, Nakagohri T, Kajiura S, Sudo K, Okamura K, Shimizu S, Shirakawa H, Kato N, Sano K, Iwai T, Fujimori N, Ueno M, Ishii H, Furuse J; Hepatobiliary and Pancreatic Oncology Group (HBPOG) of Japan Clinical Oncology Group (JCOG). Mizuno N, et al. Among authors: okamura k. Jpn J Clin Oncol. 2023 Jul 31;53(8):704-713. doi: 10.1093/jjco/hyad044. Jpn J Clin Oncol. 2023. PMID: 37248668 Free PMC article. Clinical Trial.
OBJECTIVE: JCOG1106, a randomized phase II trial conducted to compare chemoradiotherapy (S-1 concurrent radiotherapy) with (Arm B) or without (Arm A) induction chemotherapy using gemcitabine in patients with locally advanced pancreatic cancer, showed a more favorable long-term …
OBJECTIVE: JCOG1106, a randomized phase II trial conducted to compare chemoradiotherapy (S-1 concurrent radiotherapy) with (Arm B) or withou …
Adjuvant S-1 compared with observation in resected biliary tract cancer (JCOG1202, ASCOT): a multicentre, open-label, randomised, controlled, phase 3 trial.
Nakachi K, Ikeda M, Konishi M, Nomura S, Katayama H, Kataoka T, Todaka A, Yanagimoto H, Morinaga S, Kobayashi S, Shimada K, Takahashi Y, Nakagohri T, Gotoh K, Kamata K, Shimizu Y, Ueno M, Ishii H, Okusaka T, Furuse J; Hepatobiliary and Pancreatic Oncology Group of the Japan Clinical Oncology Group (JCOG-HBPOG). Nakachi K, et al. Lancet. 2023 Jan 21;401(10372):195-203. doi: 10.1016/S0140-6736(22)02038-4. Lancet. 2023. PMID: 36681415 Clinical Trial.
The main grade 3-4 adverse events in the S-1 group were decreased neutrophil count (29 [14%]) and biliary tract infection (15 [7%]). INTERPRETATION: Although long-term clinical benefit would be needed for a definitive conclusion, a significant improvement in survival sugge …
The main grade 3-4 adverse events in the S-1 group were decreased neutrophil count (29 [14%]) and biliary tract infection (15 [7%]). INTERPR …
Long-Term Outcomes of End-Flexible-Rigidscopic Transoral Surgery for Pharyngolaryngeal Cancer.
Watanabe Y, Tanaka S, Hasebe K, Hiratsuka Y, Yoshida T, Kusano J, Hori S, Okamura K, Tanaka C, Fujikawa S, Osada Y, Minoyama M. Watanabe Y, et al. Among authors: okamura k. Laryngoscope. 2023 Jun;133(6):1415-1424. doi: 10.1002/lary.30316. Epub 2022 Aug 3. Laryngoscope. 2023. PMID: 36053729
OBJECTIVE: End-flexible-rigidscopic transoral surgery (E-TOS) is a new and minimally invasive transoral surgery for resection of Tis-selected T3 pharyngolaryngeal cancers. We evaluated long-term oncological outcomes and whether postoperative voice and swallowing function w …
OBJECTIVE: End-flexible-rigidscopic transoral surgery (E-TOS) is a new and minimally invasive transoral surgery for resection of Tis-selecte …
High insertion of the right diaphragm complicated with congenital diaphragmatic hernia: A case report of rare thoracoscopic findings.
Ishimoto K, Hayashida M, Ueda M, Okamura K, Ieiri S. Ishimoto K, et al. Among authors: okamura k. Asian J Endosc Surg. 2022 Oct;15(4):854-858. doi: 10.1111/ases.13096. Epub 2022 Jun 20. Asian J Endosc Surg. 2022. PMID: 35726353
We encountered a case of high insertion of the right diaphragm complicated with congenital diaphragmatic hernia that was diagnosed based on thoracoscopic findings. A full-term male baby was suspected of having right congenital diaphragmatic hernia or diaphragmatic eventrat …
We encountered a case of high insertion of the right diaphragm complicated with congenital diaphragmatic hernia that was diagnosed based on …
91 results