Selective activation of PPARα maintains thermogenic capacity of beige adipocytes.
Egusa G, Ohno H, Nagano G, Sagawa J, Shinjo H, Yamamoto Y, Himeno N, Morita Y, Kanai A, Baba R, Kobuke K, Oki K, Yoneda M, Hattori N.
Egusa G, et al. Among authors: ohno h.
iScience. 2023 Jun 19;26(7):107143. doi: 10.1016/j.isci.2023.107143. eCollection 2023 Jul 21.
iScience. 2023.
PMID: 37456852
Free PMC article.
Beige adipocytes rapidly lose their thermogenic capacity once external cues are removed. However, long-term administration of stimulants, such as PPARgamma and beta-adrenergic receptor agonists, is unsuitable due to various side effects. ...
Beige adipocytes rapidly lose their thermogenic capacity once external cues are removed. However, long-term administration of stimula …