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1983 1
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Page 1
Long-term sequelae of therapy for childhood acute lymphoblastic leukaemia.
Ochs J, Mulhern R. Ochs J, et al. Baillieres Clin Haematol. 1994 Jun;7(2):365-76. doi: 10.1016/s0950-3536(05)80208-2. Baillieres Clin Haematol. 1994. PMID: 7803907 Review.
Common threads which run throughout the literature in this area of clinical research are the importance of young age with increased vulnerability to long-term treatment induced sequelae and the relatively large contribution of radiation as compared with chemotherapy in the …
Common threads which run throughout the literature in this area of clinical research are the importance of young age with increased vulnerab …
Late effects of antileukemic treatment.
Ochs J, Mulhern RK. Ochs J, et al. Pediatr Clin North Am. 1988 Aug;35(4):815-33. doi: 10.1016/s0031-3955(16)36511-7. Pediatr Clin North Am. 1988. PMID: 3047655 Review.
This article reviews data on the frequency and types of second malignancies, structural and functional changes in the central nervous system, endocrine effects on growth and reproduction, and psychosocial aspects of development. Most long-term survivors of ALL do not have …
This article reviews data on the frequency and types of second malignancies, structural and functional changes in the central nervous system …
Dimethyl fumarate impairs differentiated B cells and fosters central nervous system integrity in treatment of multiple sclerosis.
Traub J, Traffehn S, Ochs J, Häusser-Kinzel S, Stephan S, Scannevin R, Brück W, Metz I, Weber MS. Traub J, et al. Among authors: ochs j. Brain Pathol. 2019 Sep;29(5):640-657. doi: 10.1111/bpa.12711. Epub 2019 Mar 5. Brain Pathol. 2019. PMID: 30706542 Free PMC article.
DMF treatment may furthermore limit chronically ongoing CNS tissue damage, which may reduce long-term disability in MS apart from its relapse-reducing capacity....
DMF treatment may furthermore limit chronically ongoing CNS tissue damage, which may reduce long-term disability in MS apart from its …
A method of predicting adult height and obesity in long-term survivors of childhood acute lymphoblastic leukemia.
Schell MJ, Ochs JJ, Schriock EA, Carter M. Schell MJ, et al. Among authors: ochs jj. J Clin Oncol. 1992 Jan;10(1):128-33. doi: 10.1200/JCO.1992.10.1.128. J Clin Oncol. 1992. PMID: 1727914
PURPOSE: Short stature and obesity have been reported among long-term survivors of childhood acute lymphocytic leukemia (ALL). We examined factors that contribute to these adverse sequelae. PATIENTS AND METHODS: Serial height and weight measurements were analyzed for 91 lo …
PURPOSE: Short stature and obesity have been reported among long-term survivors of childhood acute lymphocytic leukemia (ALL). We exa …
Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital.
Walter AW, Hancock ML, Pui CH, Hudson MM, Ochs JS, Rivera GK, Pratt CB, Boyett JM, Kun LE. Walter AW, et al. Among authors: ochs js. J Clin Oncol. 1998 Dec;16(12):3761-7. doi: 10.1200/JCO.1998.16.12.3761. J Clin Oncol. 1998. PMID: 9850019
CONCLUSION: This single-institution study, with a high rate of long-term data capture, demonstrated that brain tumors are a rare, late complication of therapy for ALL. We report many more low-grade tumors than others probably because of exhaustive long-term follow-u …
CONCLUSION: This single-institution study, with a high rate of long-term data capture, demonstrated that brain tumors are a rare, lat …
Impact of three methods of treatment intensification on acute lymphoblastic leukemia in children: long-term results of St Jude total therapy study X.
Pui CH, Simone JV, Hancock ML, Evans WE, Williams DL, Bowman WP, Dahl GV, Dodge RK, Ochs J, Abromowitch M, et al. Pui CH, et al. Among authors: ochs j. Leukemia. 1992 Feb;6(2):150-7. Leukemia. 1992. PMID: 1552746 Clinical Trial.
Long-term follow-up observations are reported on 427 patients who received one of three different intensified therapies in total therapy study X for acute lymphoblastic leukemia (ALL). ...The overall survival figure, 68%, affords a benchmark for other studies assessing lon …
Long-term follow-up observations are reported on 427 patients who received one of three different intensified therapies in total ther …
Intellectual and academic achievement status after CNS relapse: a retrospective analysis of 40 children treated for acute lymphoblastic leukemia.
Mulhern RK, Ochs J, Fairclough D, Wasserman AL, Davis KS, Williams JM. Mulhern RK, et al. Among authors: ochs j. J Clin Oncol. 1987 Jun;5(6):933-40. doi: 10.1200/JCO.1987.5.6.933. J Clin Oncol. 1987. PMID: 3473185
Although the psychoeducational consequences of CNS relapse and its attendant treatment are significant, these must be balanced by consideration of the relatively low probability of long-term survival without aggressive therapy. Recognition of this type of delayed morbidity …
Although the psychoeducational consequences of CNS relapse and its attendant treatment are significant, these must be balanced by considerat …
Deterioration of intellect among children surviving leukemia: IQ test changes modify estimates of treatment toxicity.
Mulhern RK, Ochs J, Fairclough D. Mulhern RK, et al. Among authors: ochs j. J Consult Clin Psychol. 1992 Jun;60(3):477-80. doi: 10.1037//0022-006x.60.3.477. J Consult Clin Psychol. 1992. PMID: 1619103 Clinical Trial.
This study assessed the association of young age at treatment, cranial irradiation, and time since treatment with intellectual deterioration among 49 long-term survivors of childhood leukemia. Ss had been randomized to receive low-dose cranial radiation therapy or high-dos …
This study assessed the association of young age at treatment, cranial irradiation, and time since treatment with intellectual deterioration …
Comparison of neuropsychologic functioning and clinical indicators of neurotoxicity in long-term survivors of childhood leukemia given cranial radiation or parenteral methotrexate: a prospective study.
Ochs J, Mulhern R, Fairclough D, Parvey L, Whitaker J, Ch'ien L, Mauer A, Simone J. Ochs J, et al. J Clin Oncol. 1991 Jan;9(1):145-51. doi: 10.1200/JCO.1991.9.1.145. J Clin Oncol. 1991. PMID: 1985164 Clinical Trial.
We prospectively compared neuropsychologic functioning and clinical indicators of neurotoxicity in 49 consecutive childhood leukemia patients in long-term continuous complete remission (CR) who had received two different regimens of CNS prophylaxis by random assignment. .. …
We prospectively compared neuropsychologic functioning and clinical indicators of neurotoxicity in 49 consecutive childhood leukemia patient …
13 results