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A new Approach for Accurate Detection of Chromosome Rearrangements That Affect Fertility in Cattle.
Jennings RL, Griffin DK, O'Connor RE. Jennings RL, et al. Among authors: o connor re. Animals (Basel). 2020 Jan 10;10(1):114. doi: 10.3390/ani10010114. Animals (Basel). 2020. PMID: 31936776 Free PMC article.
The approach developed here identifies abnormalities that DNA sequencing will not, and has the potential to lead to long-term gains, delivering meat and milk products in a more cost-effective and environmentally-responsible manner to a growing population....
The approach developed here identifies abnormalities that DNA sequencing will not, and has the potential to lead to long-term gains, …
Diagnosis and Management of Mild Traumatic Brain Injury in Children: A Systematic Review.
Lumba-Brown A, Yeates KO, Sarmiento K, Breiding MJ, Haegerich TM, Gioia GA, Turner M, Benzel EC, Suskauer SJ, Giza CC, Joseph M, Broomand C, Weissman B, Gordon W, Wright DW, Moser RS, McAvoy K, Ewing-Cobbs L, Duhaime AC, Putukian M, Holshouser B, Paulk D, Wade SL, Herring SA, Halstead M, Keenan HT, Choe M, Christian CW, Guskiewicz K, Raksin PB, Gregory A, Mucha A, Taylor HG, Callahan JM, DeWitt J, Collins MW, Kirkwood MW, Ragheb J, Ellenbogen RG, Spinks TJ, Ganiats TG, Sabelhaus LJ, Altenhofen K, Hoffman R, Getchius T, Gronseth G, Donnell Z, O'Connor RE, Timmons SD. Lumba-Brown A, et al. Among authors: o connor re. JAMA Pediatr. 2018 Nov 1;172(11):e182847. doi: 10.1001/jamapediatrics.2018.2847. Epub 2018 Nov 5. JAMA Pediatr. 2018. PMID: 30193325
A significant body of research exists to identify features that are associated with more serious TBI-associated intracranial injury, delayed recovery from mTBI, and long-term sequelae. However, high-quality studies of treatments meant to improve mTBI outcomes are currently …
A significant body of research exists to identify features that are associated with more serious TBI-associated intracranial injury, delayed …
Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate.
Helal CJ, Arnold E, Boyden T, Chang C, Chappie TA, Fisher E, Hajos M, Harms JF, Hoffman WE, Humphrey JM, Pandit J, Kang Z, Kleiman RJ, Kormos BL, Lee CW, Lu J, Maklad N, McDowell L, McGinnis D, O'Connor RE, O'Donnell CJ, Ogden A, Piotrowski M, Schmidt CJ, Seymour PA, Ueno H, Vansell N, Verhoest PR, Yang EX. Helal CJ, et al. Among authors: o connor re. J Med Chem. 2018 Feb 8;61(3):1001-1018. doi: 10.1021/acs.jmedchem.7b01466. Epub 2018 Jan 16. J Med Chem. 2018. PMID: 29293004
Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association.
Becker LB, Aufderheide TP, Geocadin RG, Callaway CW, Lazar RM, Donnino MW, Nadkarni VM, Abella BS, Adrie C, Berg RA, Merchant RM, O'Connor RE, Meltzer DO, Holm MB, Longstreth WT, Halperin HR; American Heart Association Emergency Cardiovascular Care Committee; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Becker LB, et al. Among authors: o connor re. Circulation. 2011 Nov 8;124(19):2158-77. doi: 10.1161/CIR.0b013e3182340239. Epub 2011 Oct 3. Circulation. 2011. PMID: 21969010 Free PMC article.
For large trials designed to have a major impact on public health policy, longer-term end points such as 90 days coupled with neurocognitive and quality-of-life assessments should be considered, as should the additional costs of this approach. ...
For large trials designed to have a major impact on public health policy, longer-term end points such as 90 days coupled with neuroco …
Dangerous climate change: the role for risk research.
Lorenzoni I, Pidgeon NF, O'Connor RE. Lorenzoni I, et al. Among authors: o connor re. Risk Anal. 2005 Dec;25(6):1387-98. doi: 10.1111/j.1539-6924.2005.00686.x. Risk Anal. 2005. PMID: 16506969
The invaluable role of the climate science community, which relies on risk assessments to characterize system uncertainties and to identify limits beyond which changes may become dangerous, is acknowledged. But this alone will not suffice to develop long-term policy. Decis …
The invaluable role of the climate science community, which relies on risk assessments to characterize system uncertainties and to identify …
Alternative cardiopulmonary resuscitation devices.
O'Connor RE, Ornato JP, Wigginton J, Hunt RC, Mears G, Penner J. O'Connor RE, et al. Prehosp Emerg Care. 2003 Jan-Mar;7(1):31-41. doi: 10.1080/10903120390937067. Prehosp Emerg Care. 2003. PMID: 12540141 Review.
Even with the subsequent worldwide adoption of CPR and other advanced cardiac life support measures, long-term survival after prehospital cardiac arrest is still typically only 5%, to 10%. ...To date, only IAC (in-hospital only) and ACD have been shown to improve long-t …
Even with the subsequent worldwide adoption of CPR and other advanced cardiac life support measures, long-term survival after prehosp …
Cesarean section in a severely traumatized patient.
LeSher AR, O'Connor RE. LeSher AR, et al. Among authors: o connor re. Del Med J. 1992 Oct;64(10):619-22. Del Med J. 1992. PMID: 1426423
Massive trauma in a near-term pregnant patient challenges the emergency physician with very difficult treatment choices. We present the case of a severely traumatized pregnant female, near term, in whom the decision to proceed with a perimortem cesarean section in t …
Massive trauma in a near-term pregnant patient challenges the emergency physician with very difficult treatment choices. We present t …