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Comparing super-utilizers and lower-utilizers among commercial- and Medicare-insured adults with sickle cell disease.
MacEwan SR, Chiang C, O'Brien SH, Creary S, Lin CJ, Hyer JM, Cronin RM. MacEwan SR, et al. Among authors: o brien sh. Blood Adv. 2024 Jan 9;8(1):224-233. doi: 10.1182/bloodadvances.2023010813. Blood Adv. 2024. PMID: 37991988 Free PMC article.
Our findings demonstrate the contribution of expensive outpatient care among SCD super-utilizers, in which analyses of high expenditure have largely focused on short-term care. Future studies are needed to better understand super-utilizers in the SCD population to inform t …
Our findings demonstrate the contribution of expensive outpatient care among SCD super-utilizers, in which analyses of high expenditure have …
Sedation Practices for Lumbar Punctures in Patients With Acute Lymphoblastic Leukemia: A Multicenter Retrospective Study Using Pediatric Health Information Systems.
Wright ML, O'Brien SH, Schloss B, Stanek JR, Reed S. Wright ML, et al. Among authors: o brien sh. J Pediatr Hematol Oncol. 2022 Oct 1;44(7):e982-e987. doi: 10.1097/MPH.0000000000002446. Epub 2022 Mar 16. J Pediatr Hematol Oncol. 2022. PMID: 35293881
BACKGROUND: Sedation is often used to reduce pain and anxiety in pediatric patients with acute lymphoblastic leukemia (ALL) undergoing lumbar punctures (LPs). There is a potential for long-term effects on neurocognition with repeat sedative exposures in young children. ...
BACKGROUND: Sedation is often used to reduce pain and anxiety in pediatric patients with acute lymphoblastic leukemia (ALL) undergoing lumba …
Satisfaction with Fertility Preservation Decisions among Adolescent Males with Cancer: A Mixed Methods Study.
Theroux CI, Hill KN, Olsavsky AL, Klosky JL, Yeager ND, Audino A, O'Brien SH, Quinn GP, Gerhardt CA, Nahata L. Theroux CI, et al. Among authors: o brien sh. Cancers (Basel). 2021 Jul 16;13(14):3559. doi: 10.3390/cancers13143559. Cancers (Basel). 2021. PMID: 34298773 Free PMC article.
Survivors often regret forgoing fertility preservation (FP), and decisional dissatisfaction is associated with a lower quality of life. This mixed methods study examined short-term FP decisional satisfaction among families of male adolescents newly diagnosed with cancer wh …
Survivors often regret forgoing fertility preservation (FP), and decisional dissatisfaction is associated with a lower quality of life. This …
Conducting reproductive research during a new childhood cancer diagnosis: ethical considerations and impact on participants.
Nahata L, Morgan TL, Lipak KG, Clark OE, Yeager ND, O'Brien SH, Whiteside S, Audino AN, Gerhardt CA, Quinn GP. Nahata L, et al. Among authors: o brien sh. J Assist Reprod Genet. 2019 Sep;36(9):1787-1791. doi: 10.1007/s10815-019-01546-2. Epub 2019 Aug 1. J Assist Reprod Genet. 2019. PMID: 31372871 Free PMC article.
These findings will inform future interventions to improve long-term psychosocial and reproductive outcomes for youth with cancer....
These findings will inform future interventions to improve long-term psychosocial and reproductive outcomes for youth with cancer....
PREVAPIX-ALL: Apixaban Compared to Standard of Care for Prevention of Venous Thrombosis in Paediatric Acute Lymphoblastic Leukaemia (ALL)-Rationale and Design.
O'Brien SH, Li D, Mitchell LG, Hess T, Zee P, Yee DL, Newburger JW, Sung L, Rodriguez V. O'Brien SH, et al. Thromb Haemost. 2019 May;119(5):844-853. doi: 10.1055/s-0039-1679938. Epub 2019 Mar 12. Thromb Haemost. 2019. PMID: 30861550
Venous thromboembolic (VTE) complications in children and adolescents with acute lymphoblastic leukaemia (ALL) and T or B cell lymphoblastic lymphoma (T/B cell LL) can result not only in life-threatening acute complications but also contribute to significant long-term sequ …
Venous thromboembolic (VTE) complications in children and adolescents with acute lymphoblastic leukaemia (ALL) and T or B cell lymphoblastic …
How I treat heavy menstrual bleeding associated with anticoagulants.
Boonyawat K, O'Brien SH, Bates SM. Boonyawat K, et al. Among authors: o brien sh. Blood. 2017 Dec 14;130(24):2603-2609. doi: 10.1182/blood-2017-07-797423. Epub 2017 Nov 1. Blood. 2017. PMID: 29092828 Free article.
In the acute setting, the decision to withhold anticoagulants is based on an individual patient's risk of thrombosis and the severity of the bleeding. For women who require long-term anticoagulation, a levonorgestrel intrauterine system, tranexamic acid (during menstrual f …
In the acute setting, the decision to withhold anticoagulants is based on an individual patient's risk of thrombosis and the severity of the …
Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples.
Rajpurkar M, O'Brien SH, Haamid FW, Cooper DL, Gunawardena S, Chitlur M. Rajpurkar M, et al. Among authors: o brien sh. J Pediatr Adolesc Gynecol. 2016 Dec;29(6):537-541. doi: 10.1016/j.jpag.2016.02.002. Epub 2016 Feb 11. J Pediatr Adolesc Gynecol. 2016. PMID: 26876967 Free article.
In both patients, collaboration between the obstetrician-gynecologist or adolescent medicine specialist and the hematologist was critical for achieving acute management of the bleeding symptoms and for ensuring optimal long-term disease management. Together, these cases hi …
In both patients, collaboration between the obstetrician-gynecologist or adolescent medicine specialist and the hematologist was critical fo …
Perinatal thrombosis: implications for mothers and neonates.
O'Brien SH. O'Brien SH. Hematology Am Soc Hematol Educ Program. 2015;2015:48-52. doi: 10.1182/asheducation-2015.1.48. Hematology Am Soc Hematol Educ Program. 2015. PMID: 26637700 Review.
The importance of inherited thrombophilia in the pathophysiology and long-term outcomes of perinatal stroke requires additional study. At this time, there is no evidence to support routine extensive thrombophilia screening outside of a research setting. ...Anticoagulation …
The importance of inherited thrombophilia in the pathophysiology and long-term outcomes of perinatal stroke requires additional study …
Comparison of Thyroid Nodule Prevalence by Ultrasound in Childhood Cancer Survivors With and Without Thyroid Radiation Exposure.
Agrawal C, Guthrie L, Sturm MS, Stanek J, Martin L, Henwood-Finley M, Aldrink JH, Olshefski R, O'Brien SH. Agrawal C, et al. Among authors: o brien sh. J Pediatr Hematol Oncol. 2016 Jan;38(1):43-8. doi: 10.1097/MPH.0000000000000473. J Pediatr Hematol Oncol. 2016. PMID: 26583623 Clinical Trial.
METHODS: We recruited 60 patients with thyroid radiation and chemotherapy exposure (median age at cancer diagnosis 10.8 y) and 59 patients with chemotherapy exposure alone (median age at diagnosis 4.3 y) from our long-term survivorship clinics. Each patient had a thyroid p …
METHODS: We recruited 60 patients with thyroid radiation and chemotherapy exposure (median age at cancer diagnosis 10.8 y) and 59 patients w …