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Imaging and video of late preterm delivery by midline laparotomy due to incarcerated uterus: A case report and literature review of a rare but morbid condition.
Taylor AKL, Bartels HC, Brophy DP, O'Brien D, Corcoran SM. Taylor AKL, et al. Among authors: o brien d. Int J Gynaecol Obstet. 2024 Apr 12. doi: 10.1002/ijgo.15536. Online ahead of print. Int J Gynaecol Obstet. 2024. PMID: 38610116 Review.
Given the obstructive uropathy and associated morbidity and mortality, a plan for elective pre-term delivery at 33+6/7 weeks was made. Delivery was by midline laparotomy, normal anatomy was restored after manual evacuation of the fundus from below the sacral promontory, an …
Given the obstructive uropathy and associated morbidity and mortality, a plan for elective pre-term delivery at 33+6/7 weeks was made …
Finding "Zombies" in Your Database by Confirming Vital Status.
O'Brien DK. O'Brien DK. J Registry Manag. 2023 Summer;50(2):57-59. J Registry Manag. 2023. PMID: 37575554 Free PMC article.
Zombie cases are problematic as they contribute toward artificially high mortality rates and artificially low survival rates. They are the opposite of "immortals," a term used in the literature to indicate cases that are alive in the registry database but are actually dece …
Zombie cases are problematic as they contribute toward artificially high mortality rates and artificially low survival rates. They are the o …
Obesity-Associated Dyslipidemia Is Moderated by Habitual Intake of Marine-Derived n-3 Polyunsaturated Fatty Acids in Yup'ik Alaska Native People: A Cross-Sectional Mediation-Moderation Analysis.
Boyer BB, Wiener HW, Hopkins SE, Purnell JQ, O'Brien DM, Aliwarga T, Pomeroy JJ, Aslan JE, Thummel KE, Tiwari HK. Boyer BB, et al. Among authors: o brien dm. J Nutr. 2023 Jan;153(1):279-292. doi: 10.1016/j.tjnut.2022.10.009. Epub 2022 Dec 21. J Nutr. 2023. PMID: 36913463 Free PMC article.
BACKGROUND: Obesity leads to insulin resistance, altered lipoprotein metabolism, dyslipidemia, and cardiovascular disease. The relationship between long-term intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) and prevention of cardiometabolic disease remains unresolved. …
BACKGROUND: Obesity leads to insulin resistance, altered lipoprotein metabolism, dyslipidemia, and cardiovascular disease. The relationship …
Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography.
Magor-Elliott SRM, Alamoudi A, Chamley RR, Xu H, Wellalagodage T, McDonald RP, O'Brien D, Collins J, Coombs B, Winchester J, Sellon E, Xie C, Sandhu D, Fullerton CJ, Couper JH, Smith NMJ, Richmond G, Cassar MP, Raman B, Talbot NP, Bennett AN, Nicol ED, Ritchie GAD, Petousi N, Holdsworth DA, Robbins PA. Magor-Elliott SRM, et al. Among authors: o brien d. J Appl Physiol (1985). 2022 Nov 1;133(5):1175-1191. doi: 10.1152/japplphysiol.00436.2022. Epub 2022 Sep 29. J Appl Physiol (1985). 2022. PMID: 36173325 Free PMC article.
The longer-term effects of COVID-19 on lung physiology remain poorly understood. ...
The longer-term effects of COVID-19 on lung physiology remain poorly understood. ...
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.
Kotanidis CP, Xie C, Alexander D, Rodrigues JCL, Burnham K, Mentzer A, O'Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou EK, Badi I, Lyasheva M, Shirodaria C, Lumley SF, Constantinides B, Sanderson N, Rodger G, Chau KK, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson BJ, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho LP, Neubauer S, Newby DE, Channon KM, Deanfield J, Antoniades C; COMBAT Consortium; ORFAN investigators. Kotanidis CP, et al. Lancet Digit Health. 2022 Oct;4(10):e705-e716. doi: 10.1016/S2589-7500(22)00132-7. Epub 2022 Aug 26. Lancet Digit Health. 2022. PMID: 36038496 Free PMC article.
BACKGROUND: Direct evaluation of vascular inflammation in patients with COVID-19 would facilitate more efficient trials of new treatments and identify patients at risk of long-term complications who might respond to treatment. We aimed to develop a novel artificial intelli …
BACKGROUND: Direct evaluation of vascular inflammation in patients with COVID-19 would facilitate more efficient trials of new treatments an …
In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions.
Nicolas CT, VanLith CJ, Hickey RD, Du Z, Hillin LG, Guthman RM, Cao WJ, Haugo B, Lillegard A, Roy D, Bhagwate A, O'Brien D, Kocher JP, Kaiser RA, Russell SJ, Lillegard JB. Nicolas CT, et al. Among authors: o brien d. Nat Commun. 2022 Aug 25;13(1):5012. doi: 10.1038/s41467-022-32576-7. Nat Commun. 2022. PMID: 36008405 Free PMC article.
Here we demonstrate cure of HT1 by direct, in vivo administration of a therapeutic lentiviral vector targeting the expression of a human fumarylacetoacetate hydrolase (FAH) transgene in the porcine model of HT1. This therapy is well tolerated and provides stable long-term …
Here we demonstrate cure of HT1 by direct, in vivo administration of a therapeutic lentiviral vector targeting the expression of a human fum …
Evaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of the RESCUEicp Randomized Clinical Trial.
Kolias AG, Adams H, Timofeev IS, Corteen EA, Hossain I, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Posti JP, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ, Hutchinson PJ; RESCUEicp Trial Collaborators. Kolias AG, et al. JAMA Neurol. 2022 Jul 1;79(7):664-671. doi: 10.1001/jamaneurol.2022.1070. JAMA Neurol. 2022. PMID: 35666526 Free PMC article. Clinical Trial.
IMPORTANCE: Trials often assess primary outcomes of traumatic brain injury at 6 months. Longer-term data are needed to assess outcomes for patients receiving surgical vs medical treatment for traumatic intracranial hypertension. ...
IMPORTANCE: Trials often assess primary outcomes of traumatic brain injury at 6 months. Longer-term data are needed to assess outcome …
Global genetic diversity status and trends: towards a suite of Essential Biodiversity Variables (EBVs) for genetic composition.
Hoban S, Archer FI, Bertola LD, Bragg JG, Breed MF, Bruford MW, Coleman MA, Ekblom R, Funk WC, Grueber CE, Hand BK, Jaffé R, Jensen E, Johnson JS, Kershaw F, Liggins L, MacDonald AJ, Mergeay J, Miller JM, Muller-Karger F, O'Brien D, Paz-Vinas I, Potter KM, Razgour O, Vernesi C, Hunter ME. Hoban S, et al. Among authors: o brien d. Biol Rev Camb Philos Soc. 2022 Aug;97(4):1511-1538. doi: 10.1111/brv.12852. Epub 2022 Apr 12. Biol Rev Camb Philos Soc. 2022. PMID: 35415952 Free PMC article. Review.
With these advances, genetic composition monitoring is starting to be integrated into global conservation policy, which can help support the foundation of all biodiversity and species' long-term persistence in the face of environmental change. We conclude with a summary of …
With these advances, genetic composition monitoring is starting to be integrated into global conservation policy, which can help support the …
Systemic Steroids for Otolaryngology-Head and Neck Surgery Disorders: An Evidence-Based Primer for Clinicians.
McCoul ED, Megwalu UC, Joe S, Gray R, O'Brien DC, Ference EH, Lee VS, Patel PS, Figueroa-Morales MA, Shin JJ, Brenner MJ. McCoul ED, et al. Among authors: o brien dc. Otolaryngol Head Neck Surg. 2023 Apr;168(4):643-657. doi: 10.1177/01945998221087664. Epub 2023 Feb 5. Otolaryngol Head Neck Surg. 2023. PMID: 35349383
IMPLICATIONS FOR PRACTICE: Clinicians should bring an evidence-informed lens to SCS prescribing to best counsel patients regarding the risks, anticipated benefits, and limited data on long-term effects. Alternate routes of corticosteroid administration-such as sprays, drop …
IMPLICATIONS FOR PRACTICE: Clinicians should bring an evidence-informed lens to SCS prescribing to best counsel patients regarding the risks …
Long-Term Complications in Youth-Onset Type 2 Diabetes.
TODAY Study Group; Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P. TODAY Study Group, et al. N Engl J Med. 2021 Jul 29;385(5):416-426. doi: 10.1056/NEJMoa2100165. N Engl J Med. 2021. PMID: 34320286 Free PMC article.
70 results