Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming.
Pateras IS, Williams C, Gianniou DD, Margetis AT, Avgeris M, Rousakis P, Legaki AI, Mirtschink P, Zhang W, Panoutsopoulou K, Delis AD, Pagakis SN, Tang W, Ambs S, Warpman Berglund U, Helleday T, Varvarigou A, Chatzigeorgiou A, Nordström A, Tsitsilonis OE, Trougakos IP, Gilthorpe JD, Frisan T.
Pateras IS, et al. Among authors: nordstrom a.
J Transl Med. 2023 Mar 3;21(1):169. doi: 10.1186/s12967-023-03935-9.
J Transl Med. 2023.
PMID: 36869333
Free PMC article.
However, the molecular mechanism(s) by which fasting, or short-term starvation (STS), improves the efficacy of CT is poorly characterized. ...CONCLUSIONS: Our in vitro, in vivo and clinical findings provide a robust rationale for clinical trials on the therapeutic benefit …
However, the molecular mechanism(s) by which fasting, or short-term starvation (STS), improves the efficacy of CT is poorly character …