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2012 1
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Page 1
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis.
Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, Myers SR, Nigrovic LE, Garro A, Brown KM, Quayle KS, Trainor JL, Tzimenatos L, Bennett JE, DePiero AD, Kwok MY, Perry CS 3rd, Olsen CS, Casper TC, Dean JM, Glaser NS; PECARN DKA FLUID Study Group. Kuppermann N, et al. Among authors: nigrovic le. N Engl J Med. 2018 Jun 14;378(24):2275-2287. doi: 10.1056/NEJMoa1716816. N Engl J Med. 2018. PMID: 29897851 Free PMC article. Clinical Trial.
Secondary outcomes included clinically apparent brain injury during treatment for diabetic ketoacidosis, short-term memory during treatment for diabetic ketoacidosis, and memory and IQ 2 to 6 months after recovery from diabetic ketoacidosis. ...No significant differences a …
Secondary outcomes included clinically apparent brain injury during treatment for diabetic ketoacidosis, short-term memory during tre …
Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitis in children: a multicentre prospective cohort study.
Nigrovic LE, Chun TH, Vargas SE, Caffrey AR, Halperin JJ, Race JA, Ott U, Morrison BL, Fuller BJ, VanBuren JM, Lyme Net P. Nigrovic LE, et al. BMJ Open. 2023 Feb 28;13(2):e071141. doi: 10.1136/bmjopen-2022-071141. BMJ Open. 2023. PMID: 36854594 Free PMC article.
Our goal is to compare oral doxycycline with intravenous ceftriaxone for the treatment of Lyme meningitis on short-term recovery and long-term quality of life. METHODS AND ANALYSIS: We are performing a prospective cohort study at 20 US paediatric centres located in …
Our goal is to compare oral doxycycline with intravenous ceftriaxone for the treatment of Lyme meningitis on short-term recovery and …
A Systematic Review and Meta-Analysis of the Management and Outcomes of Isolated Skull Fractures in Children.
Bressan S, Marchetto L, Lyons TW, Monuteaux MC, Freedman SB, Da Dalt L, Nigrovic LE. Bressan S, et al. Among authors: nigrovic le. Ann Emerg Med. 2018 Jun;71(6):714-724.e2. doi: 10.1016/j.annemergmed.2017.10.014. Epub 2017 Nov 24. Ann Emerg Med. 2018. PMID: 29174834 Free PMC article.
STUDY OBJECTIVE: Most studies of children with isolated skull fractures have been relatively small, and rare adverse outcomes may have been missed. Our aim is to quantify the frequency of short-term adverse outcomes of children with isolated skull fractures. METHODS: PubMe …
STUDY OBJECTIVE: Most studies of children with isolated skull fractures have been relatively small, and rare adverse outcomes may have been …
Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections.
Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network. Cruz AT, et al. Among authors: nigrovic le. JAMA Pediatr. 2017 Nov 6;171(11):e172927. doi: 10.1001/jamapediatrics.2017.2927. Epub 2017 Nov 6. JAMA Pediatr. 2017. PMID: 28892537 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: Planned secondary analysis of a prospective observational cohort study comprising 26 emergency departments in the Pediatric Emergency Care Applied Research Network from 2008 to 2013. We included febrile (38C), previously healthy, full-term …
DESIGN, SETTING, AND PARTICIPANTS: Planned secondary analysis of a prospective observational cohort study comprising 26 emergency department …
Factors Associated with Adverse Outcomes among Febrile Young Infants with Invasive Bacterial Infections.
Pruitt CM, Neuman MI, Shah SS, Shabanova V, Woll C, Wang ME, Alpern ER, Williams DJ, Sartori L, Desai S, Leazer RC, Marble RD, McCulloh RJ, DePorre AG, Rooholamini SN, Lumb CE, Balamuth F, Shin S, Aronson PL; Febrile Young Infant Research Collaborative. Pruitt CM, et al. J Pediatr. 2019 Jan;204:177-182.e1. doi: 10.1016/j.jpeds.2018.08.066. Epub 2018 Oct 5. J Pediatr. 2019. PMID: 30297292 Free PMC article.

On adjusted analysis, bacterial meningitis (aOR 16.3, 95% CI 6.5-41.0; P < .001), prematurity (aOR 7.1, 95% CI 2.6-19.7; P < .001), and ill appearance (aOR 3.8, 95% CI 1.6-9.1; P = .002) were associated with adverse outcomes. Among infants who were born at term, not

…

On adjusted analysis, bacterial meningitis (aOR 16.3, 95% CI 6.5-41.0; P < .001), prematurity (aOR 7.1, 95% CI 2.6-19.7; P < .001), an

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Impact of the COVID-19 pandemic on pediatric faculty: a report from nine academic institutions.
O'Connor TM, Guaman MC, Randell KA, Keenan HT, Snowden J, Mack JW, Camp EA, Perez O, Chang ML, Myers AL, Nigrovic LE, O'Toole J, Reed JL, Reese J, Rosenberg AR, Slater AC, Wootton SH, Ziniel SI, Yost HJ, Murray KO, Shekerdemian L, Chumpitazi CE. O'Connor TM, et al. Among authors: nigrovic le. Pediatr Res. 2024 Feb;95(3):775-784. doi: 10.1038/s41390-023-02726-8. Epub 2023 Jul 15. Pediatr Res. 2024. PMID: 37454186
COVID-19 was particularly disruptive to research outlook. Mitigation strategies are needed to minimize the long-term impacts on academic pediatric careers. IMPACT: The COVID-19 pandemic most negatively impacted work productivity of academic pediatric faculty with caregivin …
COVID-19 was particularly disruptive to research outlook. Mitigation strategies are needed to minimize the long-term impacts on acade …
Frequency and Risk Factors of Acute Kidney Injury During Diabetic Ketoacidosis in Children and Association With Neurocognitive Outcomes.
Myers SR, Glaser NS, Trainor JL, Nigrovic LE, Garro A, Tzimenatos L, Quayle KS, Kwok MY, Rewers A, Stoner MJ, Schunk JE, McManemy JK, Brown KM, DePiero AD, Olsen CS, Casper TC, Ghetti S, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group. Myers SR, et al. Among authors: nigrovic le. JAMA Netw Open. 2020 Dec 1;3(12):e2025481. doi: 10.1001/jamanetworkopen.2020.25481. JAMA Netw Open. 2020. PMID: 33275152 Free PMC article.
Children with AKI, compared with those without, had lower scores on tests of short-term memory during DKA (mean [SD] digit span recall: 6.8 [2.4] vs 7.6 [2.2]; P = .02) and lower mean (SD) IQ scores 3 to 6 months after recovery from DKA (100.0 [12.2] vs 103.5 [13.2]; P = . …
Children with AKI, compared with those without, had lower scores on tests of short-term memory during DKA (mean [SD] digit span recal …
The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants.
Nigrovic LE, Mahajan PV, Blumberg SM, Browne LR, Linakis JG, Ruddy RM, Bennett JE, Rogers AJ, Tzimenatos L, Powell EC, Alpern ER, Casper TC, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). Nigrovic LE, et al. Pediatrics. 2017 Jul;140(1):e20170695. doi: 10.1542/peds.2017-0695. Epub 2017 Jun 6. Pediatrics. 2017. PMID: 28759413 Free PMC article.
METHODS: We performed a planned secondary analysis of a prospective cohort of non-critically ill, febrile, full-term infants 60 days of age presenting to 1 of 26 participating emergency departments in the Pediatric Emergency Care Applied Research Network. ...
METHODS: We performed a planned secondary analysis of a prospective cohort of non-critically ill, febrile, full-term infants 60 days …
Factors influencing neurological outcome of children with bacterial meningitis at the emergency department.
Bargui F, D'Agostino I, Mariani-Kurkdjian P, Alberti C, Doit C, Bellier N, Morin L, Galli Gibertini G, Smail A, Zanin A, Lorrot M, Dauger S, Neve M, Faye A, Armoogum P, Bourrillon A, Bingen E, Mercier JC, Bonacorsi S, Nigrovic LE, Titomanlio L. Bargui F, et al. Among authors: nigrovic le. Eur J Pediatr. 2012 Sep;171(9):1365-71. doi: 10.1007/s00431-012-1733-5. Epub 2012 Apr 19. Eur J Pediatr. 2012. PMID: 22527566
We performed a cohort study of children who survived bacterial meningitis after the neonatal period at a single pediatric center in France over a 10-year period (1995-2004) to identify predictors of death and long-term neurological deficits in children with bacterial menin …
We performed a cohort study of children who survived bacterial meningitis after the neonatal period at a single pediatric center in France o …
11 results