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Long-term effects of high-dose systemic corticosteroids on growth and bone mineral density in patients treated for childhood interstitial lung disease (chILD).
Ring AM, Buchvald FF, Main KM, Oturai P, Nielsen KG. Ring AM, et al. Among authors: nielsen kg. Pediatr Pulmonol. 2024 Apr;59(4):964-973. doi: 10.1002/ppul.26858. Epub 2024 Jan 19. Pediatr Pulmonol. 2024. PMID: 38240460
Excess body fat (>30% in females, >25% in males) was found in 58% of patients. CONCLUSION: Long-term treatment with sCCS did not cause significant long-term reduction of height but showed subtle effects on fat mass percentage and BMD. Given the severity of chI …
Excess body fat (>30% in females, >25% in males) was found in 58% of patients. CONCLUSION: Long-term treatment with sCCS did no …
Diffuse alveolar haemorrhage in children: an international multicentre study.
Ring AM, Schwerk N, Kiper N, Aslan AT, Aurora P, Ayats R, Azevedo I, Bandeira T, Carlens J, Castillo-Corullon S, Cobanoglu N, Elnazir B, Emiralioğlu N, Eyuboglu TS, Fayon M, Gursoy TR, Hogg C, Kötz K, Karadag B, Látalová V, Krenke K, Lange J, Manali ED, Osona B, Papiris S, Proesmann M, Reix P, Roditis L, Rubak S, Rumman N, Snijders D, Stehling F, Weiss L, Yalcın E, Zirek F, Bush A, Clement A, Griese M, Buchvald FF, Nathan N, Nielsen KG. Ring AM, et al. Among authors: nielsen kg. ERJ Open Res. 2023 Apr 24;9(2):00733-2022. doi: 10.1183/23120541.00733-2022. eCollection 2023 Mar. ERJ Open Res. 2023. PMID: 37101741 Free PMC article.
The most frequent medical treatment was systemic corticosteroids (93%), hydroxychloroquine (35%) and azathioprine (27%). Overall mortality was 13%. Long-term data demonstrated persistent abnormal radiology and a limited improvement in lung function. ...This large internati …
The most frequent medical treatment was systemic corticosteroids (93%), hydroxychloroquine (35%) and azathioprine (27%). Overall mortality w …
The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN.
Raidt J, Maitre B, Pennekamp P, Altenburg J, Anagnostopoulou P, Armengot M, Bloemsma LD, Boon M, Borrelli M, Brinkmann F, Carr SB, Carroll MP, Castillo-Corullón S, Coste A, Cutrera R, Dehlink E, Destouches DMS, Di Cicco ME, Dixon L, Emiralioglu N, Erdem Eralp E, Haarman EG, Hogg C, Karadag B, Kobbernagel HE, Lorent N, Mall MA, Marthin JK, Martinu V, Narayanan M, Ozcelik U, Peckham D, Pifferi M, Pohunek P, Polverino E, Range S, Ringshausen FC, Robson E, Roehmel J, Rovira-Amigo S, Santamaria F, Schlegtendal A, Szépfalusi Z, Tempels P, Thouvenin G, Ullmann N, Walker WT, Wetzke M, Yiallouros P, Omran H, Nielsen KG. Raidt J, et al. Among authors: nielsen kg. ERJ Open Res. 2022 Aug 15;8(3):00139-2022. doi: 10.1183/23120541.00139-2022. eCollection 2022 Jul. ERJ Open Res. 2022. PMID: 35983540 Free PMC article.
A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia.
Holgersen MG, Marthin JK, Johansen HK, Nielsen KG. Holgersen MG, et al. Among authors: nielsen kg. Chron Respir Dis. 2021 Jan-Dec;18:14799731211061600. doi: 10.1177/14799731211061600. Chron Respir Dis. 2021. PMID: 34854775 Free PMC article.
Conclusion The prevalence of Achromobacter species in patients with PCD is in line with what has been reported in cystic fibrosis and can occur transiently, intermittently, or develop into a serious persistent lung infection associated with long-term antibiotic treatment.. …
Conclusion The prevalence of Achromobacter species in patients with PCD is in line with what has been reported in cystic fibrosis and can oc …
Withdrawal of dornase alfa increases ventilation inhomogeneity in children with cystic fibrosis.
Voldby C, Green K, Philipsen L, Sandvik RM, Skov M, Buchvald F, Pressler T, Nielsen KG. Voldby C, et al. Among authors: nielsen kg. J Cyst Fibros. 2021 Nov;20(6):949-956. doi: 10.1016/j.jcf.2021.02.004. Epub 2021 Feb 19. J Cyst Fibros. 2021. PMID: 33619014 Free article. Clinical Trial.
Hence, adherence to dornase alfa optimally needs to be addressed when using LCI and spirometric parameters as endpoints, even in short-term clinical trials....
Hence, adherence to dornase alfa optimally needs to be addressed when using LCI and spirometric parameters as endpoints, even in short-te …
Proceedings of the 4th BEAT-PCD Conference and 5th PCD Training School.
Gardner LE, Horton KL, Shoemark A, Lucas JS, Nielsen KG, Kobbernagel H, Rubbo B, Hirst RA, Kouis P, Ullmann N, Reula A, Rumman N, Mitchison HM, Pinto A, Richardson C, Schmidt A, Thompson J, Gaupmann R, Dabrowski M, Mill P, Carr SB, Norris DP, Kuehni CE, Goutaki M, Hogg C. Gardner LE, et al. Among authors: nielsen kg. BMC Proc. 2020 Jun 19;14(Suppl 8):7. doi: 10.1186/s12919-020-00191-3. eCollection 2020. BMC Proc. 2020. PMID: 32577127 Free PMC article.
Long-Term Lung Function and Exercise Capacity in Postinfectious chILD.
Sisman Y, Buchvald FF, Ring AM, Wassilew K, Nielsen KG. Sisman Y, et al. Among authors: nielsen kg. Pediatr Allergy Immunol Pulmonol. 2019 Mar 1;32(1):4-11. doi: 10.1089/ped.2018.0973. Epub 2019 Mar 28. Pediatr Allergy Immunol Pulmonol. 2019. PMID: 31032143 Free PMC article.
Background: Severe postinfectious diffuse pulmonary disease may clinically mimic other entities of children's interstitial lung disease and is clinically challenging comprising various disease severities despite treatment. Long-term lung function trend and physical capacit …
Background: Severe postinfectious diffuse pulmonary disease may clinically mimic other entities of children's interstitial lung disease and …
One-year evolution and variability in multiple-breath washout indices in children and young adults with primary ciliary dyskinesia.
Kobbernagel HE, Green K, Ring AM, Buchvald FF, Rosthøj S, Gustafsson PM, Nielsen KG. Kobbernagel HE, et al. Among authors: nielsen kg. Eur Clin Respir J. 2019 Mar 26;6(1):1591841. doi: 10.1080/20018525.2019.1591841. eCollection 2019. Eur Clin Respir J. 2019. PMID: 30949311 Free PMC article.
Background and objective: Cross-sectional and longer-term studies have demonstrated abnormal yet stable multiple-breath inert gas washout (MBW) indices in patients with primary ciliary dyskinesia (PCD). This study aimed to assess the intermediate term evolution and …
Background and objective: Cross-sectional and longer-term studies have demonstrated abnormal yet stable multiple-breath inert gas was …
Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School.
Farley H, Rubbo B, Bukowy-Bieryllo Z, Fassad M, Goutaki M, Harman K, Hogg C, Kuehni CE, Lopes S, Nielsen KG, Norris DP, Reula A, Rumman N, Shoemark A, Wilkins H, Wisse A, Lucas JS, Marthin JK. Farley H, et al. Among authors: nielsen kg. BMC Proc. 2018 Dec 18;12(Suppl 16):64. doi: 10.1186/s12919-018-0161-6. eCollection 2018. BMC Proc. 2018. PMID: 30807620 Free PMC article.
'Better Experimental Approaches to Treat Primary Ciliary Dyskinesia' (BEAT-PCD) is a network of scientists and clinicians coordinating research from basic science through to clinical care with the intention of developing treatments and diagnostics that lead to improved long-te …
'Better Experimental Approaches to Treat Primary Ciliary Dyskinesia' (BEAT-PCD) is a network of scientists and clinicians coordinating resea …
Ventilation inhomogeneity and NO and CO diffusing capacity in ex-premature school children.
Sørensen JK, Buchvald F, Berg AK, Robinson PD, Nielsen KG. Sørensen JK, et al. Among authors: nielsen kg. Respir Med. 2018 Jul;140:94-100. doi: 10.1016/j.rmed.2018.06.006. Epub 2018 Jun 6. Respir Med. 2018. PMID: 29957288 Free article.
Multiple breath nitrogen washout (N2MBW) and NO diffusing capacity (DLNO) measurements may provide new insight into long-term pulmonary and vascular impairment in bronchopulmonary dysplasia (BPD). METHODS: We examined a randomly selected group of 70 ex-premature children ( …
Multiple breath nitrogen washout (N2MBW) and NO diffusing capacity (DLNO) measurements may provide new insight into long-term pulmona …
28 results