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Protocol for a pilot cluster randomised controlled trial of a multicomponent sustainable return to work IGLOo intervention.
Davis O, Dawson J, Degerdon L, Delgadillo J, Kadam U, Nielsen K, Sinclair A, Yarker J, Munir F. Davis O, et al. Among authors: nielsen k. Pilot Feasibility Stud. 2024 Feb 3;10(1):23. doi: 10.1186/s40814-023-01439-3. Pilot Feasibility Stud. 2024. PMID: 38308380 Free PMC article.
BACKGROUND: Long-term sickness costs businesses in the United Kingdom (UK) approximately 7 billion per annum. Most long-term sickness absences are attributed to common mental health conditions, which are also highly prevalent in people with acute or musculoskeletal …
BACKGROUND: Long-term sickness costs businesses in the United Kingdom (UK) approximately 7 billion per annum. Most long-term s …
Long-term effects of high-dose systemic corticosteroids on growth and bone mineral density in patients treated for childhood interstitial lung disease (chILD).
Ring AM, Buchvald FF, Main KM, Oturai P, Nielsen KG. Ring AM, et al. Among authors: nielsen kg. Pediatr Pulmonol. 2024 Apr;59(4):964-973. doi: 10.1002/ppul.26858. Epub 2024 Jan 19. Pediatr Pulmonol. 2024. PMID: 38240460
Excess body fat (>30% in females, >25% in males) was found in 58% of patients. CONCLUSION: Long-term treatment with sCCS did not cause significant long-term reduction of height but showed subtle effects on fat mass percentage and BMD. Given the severity of chI …
Excess body fat (>30% in females, >25% in males) was found in 58% of patients. CONCLUSION: Long-term treatment with sCCS did no …
Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis.
Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H; DUPRO Steering Committee and DUPLEX Investigators. Rheault MN, et al. N Engl J Med. 2023 Dec 28;389(26):2436-2445. doi: 10.1056/NEJMoa2308550. Epub 2023 Nov 3. N Engl J Med. 2023. PMID: 37921461 Clinical Trial.
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The efficacy and safety of longer-term treatment with sparsentan for FSGS are unknown. METHODS: In this phase 3 trial, we enrolled patient …
In an 8-week, phase 2 trial, sparsentan, a dual endothelin-angiotensin receptor antagonist, reduced proteinuria in patients with FSGS. The e …
Diffuse alveolar haemorrhage in children: an international multicentre study.
Ring AM, Schwerk N, Kiper N, Aslan AT, Aurora P, Ayats R, Azevedo I, Bandeira T, Carlens J, Castillo-Corullon S, Cobanoglu N, Elnazir B, Emiralioğlu N, Eyuboglu TS, Fayon M, Gursoy TR, Hogg C, Kötz K, Karadag B, Látalová V, Krenke K, Lange J, Manali ED, Osona B, Papiris S, Proesmann M, Reix P, Roditis L, Rubak S, Rumman N, Snijders D, Stehling F, Weiss L, Yalcın E, Zirek F, Bush A, Clement A, Griese M, Buchvald FF, Nathan N, Nielsen KG. Ring AM, et al. Among authors: nielsen kg. ERJ Open Res. 2023 Apr 24;9(2):00733-2022. doi: 10.1183/23120541.00733-2022. eCollection 2023 Mar. ERJ Open Res. 2023. PMID: 37101741 Free PMC article.
The most frequent medical treatment was systemic corticosteroids (93%), hydroxychloroquine (35%) and azathioprine (27%). Overall mortality was 13%. Long-term data demonstrated persistent abnormal radiology and a limited improvement in lung function. ...This large internati …
The most frequent medical treatment was systemic corticosteroids (93%), hydroxychloroquine (35%) and azathioprine (27%). Overall mortality w …
Safety interventions for the prevention of accidents at work: A systematic review.
Dyreborg J, Lipscomb HJ, Nielsen K, Törner M, Rasmussen K, Frydendall KB, Bay H, Gensby U, Bengtsen E, Guldenmund F, Kines P. Dyreborg J, et al. Among authors: nielsen k. Campbell Syst Rev. 2022 Jun 1;18(2):e1234. doi: 10.1002/cl2.1234. eCollection 2022 Jun. Campbell Syst Rev. 2022. PMID: 36911341 Free PMC article. Review.
Effects that are more modest were observed (in short follow-up) for safety climate interventions, using techniques such as feedback or leadership training to improve safety communication. There was limited evidence for a strong effect at medium-term with more intense couns …
Effects that are more modest were observed (in short follow-up) for safety climate interventions, using techniques such as feedback or leade …
Microvascular endothelial function following cessation of long-term oral contraceptive pill use: A case report.
Turner CG, Stanhewicz AE, Nielsen KE, Wong BJ. Turner CG, et al. Among authors: nielsen ke. Exp Physiol. 2023 Jan;108(1):5-11. doi: 10.1113/EP090861. Epub 2022 Nov 30. Exp Physiol. 2023. PMID: 36448409 Free PMC article.
What insights does it reveal? Our findings suggest that cessation of long-term, fourth-generation oral contraceptive pill use improves endothelial function within 20 months of cessation. ...Overall, these data suggest an improvement in endothelial and microvascular functio …
What insights does it reveal? Our findings suggest that cessation of long-term, fourth-generation oral contraceptive pill use improve …
Women's perceptions of cardiovascular risk after preeclampsia: a qualitative study.
Nielsen LM, Hauge MG, Ersbøll AS, Johansen M, Linde JJ, Damm P, Nielsen KK. Nielsen LM, et al. Among authors: nielsen kk. BMC Pregnancy Childbirth. 2022 Nov 11;22(1):832. doi: 10.1186/s12884-022-05179-9. BMC Pregnancy Childbirth. 2022. PMID: 36368968 Free PMC article.
Little is known about how these women perceive the condition and the associated long-term risks. We examined the experiences and perceptions of preeclampsia and the increased risk of cardiovascular disease (CVD) later in life among Danish women with previous preeclampsia a …
Little is known about how these women perceive the condition and the associated long-term risks. We examined the experiences and perc …
Microwave-assisted synthesis of [52Mn]Mn-porphyrins: Applications in cell and liposome radiolabelling.
Gawne PJ, Pinto SMA, Nielsen KM, Keeling GP, Pereira MM, T M de Rosales R. Gawne PJ, et al. Among authors: nielsen km. Nucl Med Biol. 2022 Nov-Dec;114-115:6-17. doi: 10.1016/j.nucmedbio.2022.08.006. Epub 2022 Sep 2. Nucl Med Biol. 2022. PMID: 36088876 Free PMC article.
We hypothesised that metalation with the positron emission tomography (PET) radionuclide (52)Mn (t(1/2) = 5.6 d) would allow long-term in vivo biodistribution studies of Mn-porphyrins, as well as a method to label and track cells/liposomes, but methods for fast and efficie …
We hypothesised that metalation with the positron emission tomography (PET) radionuclide (52)Mn (t(1/2) = 5.6 d) would allow long-term …
149 results