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Screening of GPCR drugs for repurposing in breast cancer.
Abdulkareem NM, Bhat R, Powell RT, Chikermane S, Yande S, Trinh L, Abdelnasser HY, Tabassum M, Ruiz A, Sobieski M, Nguyen ND, Park JH, Johnson CA, Kaipparettu BA, Bond RA, Johnson M, Stephan C, Trivedi MV. Abdulkareem NM, et al. Among authors: nguyen nd. Front Pharmacol. 2022 Dec 6;13:1049640. doi: 10.3389/fphar.2022.1049640. eCollection 2022. Front Pharmacol. 2022. PMID: 36561339 Free PMC article.
We focused on beta-adrenergic receptor-targeting nebivolol as a candidate, primarily because of the potential role of these receptors in BC and its excellent long-term safety profile. The effects of nebivolol were validated in an independent assay in all the cell line mode …
We focused on beta-adrenergic receptor-targeting nebivolol as a candidate, primarily because of the potential role of these receptors in BC …
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB.
Kumar A, Aglyamova G, Yim YY, Bailey AO, Lynch HM, Powell RT, Nguyen ND, Rosenthal Z, Zhao WN, Li Y, Chen J, Fan S, Lee H, Russell WK, Stephan C, Robison AJ, Haggarty SJ, Nestler EJ, Zhou J, Machius M, Rudenko G. Kumar A, et al. Among authors: nguyen nd. Nucleic Acids Res. 2022 Sep 9;50(16):9548-9567. doi: 10.1093/nar/gkac710. Nucleic Acids Res. 2022. PMID: 36039764 Free PMC article.
The AP1 transcription factor deltaFOSB, a splice variant of FOSB, accumulates in the brain in response to chronic insults such as exposure to drugs of abuse, depression, Alzheimer's disease and tardive dyskinesias, and mediates subsequent long-term neuroadaptations. deltaF …
The AP1 transcription factor deltaFOSB, a splice variant of FOSB, accumulates in the brain in response to chronic insults such as exposure t …
Long-term consequences of one anastomosis gastric bypass on esogastric mucosa in a preclinical rat model.
Siebert M, Ribeiro-Parenti L, Nguyen ND, Hourseau M, Duchêne B, Humbert L, Jonckheere N, Nuel G, Chevallier JM, Duboc H, Rainteau D, Msika S, Kapel N, Couvelard A, Bado A, Le Gall M. Siebert M, et al. Among authors: nguyen nd. Sci Rep. 2020 Apr 30;10(1):7393. doi: 10.1038/s41598-020-64425-2. Sci Rep. 2020. PMID: 32355175 Free PMC article.
Although bariatric surgery is proven to sustain weight loss in morbidly obese patients, long-term adverse effects have yet to be fully characterized. This study compared the long-term consequences of two common forms of bariatric surgery: one-anastomosis gastric byp …
Although bariatric surgery is proven to sustain weight loss in morbidly obese patients, long-term adverse effects have yet to be full …
Carboxysome encapsulation of the CO2-fixing enzyme Rubisco in tobacco chloroplasts.
Long BM, Hee WY, Sharwood RE, Rae BD, Kaines S, Lim YL, Nguyen ND, Massey B, Bala S, von Caemmerer S, Badger MR, Price GD. Long BM, et al. Among authors: nguyen nd. Nat Commun. 2018 Sep 3;9(1):3570. doi: 10.1038/s41467-018-06044-0. Nat Commun. 2018. PMID: 30177711 Free PMC article.
A long-term strategy to enhance global crop photosynthesis and yield involves the introduction of cyanobacterial CO(2)-concentrating mechanisms (CCMs) into plant chloroplasts. ...
A long-term strategy to enhance global crop photosynthesis and yield involves the introduction of cyanobacterial CO(2)-concentrating …
Multimodal cortical and subcortical exercise compared with treadmill training for spinal cord injury.
Martinez SA, Nguyen ND, Bailey E, Doyle-Green D, Hauser HA, Handrakis JP, Knezevic S, Marett C, Weinman J, Romero AF, Santiago TM, Yang AH, Yung L, Asselin PK, Weir JP, Kornfeld SD, Bauman WA, Spungen AM, Harel NY. Martinez SA, et al. Among authors: nguyen nd. PLoS One. 2018 Aug 9;13(8):e0202130. doi: 10.1371/journal.pone.0202130. eCollection 2018. PLoS One. 2018. PMID: 30092092 Free PMC article. Clinical Trial.
CONCLUSION: In participants with chronic incomplete SCI, a novel mix of multimodal exercises incorporating balance exercises with skilled upper extremity exercises showed no benefit compared to an active control program of body weight-supported treadmill training. To improve part …
CONCLUSION: In participants with chronic incomplete SCI, a novel mix of multimodal exercises incorporating balance exercises with skilled up …
Reminder: RMSSD and SD1 are identical heart rate variability metrics.
Ciccone AB, Siedlik JA, Wecht JM, Deckert JA, Nguyen ND, Weir JP. Ciccone AB, et al. Among authors: nguyen nd. Muscle Nerve. 2017 Oct;56(4):674-678. doi: 10.1002/mus.25573. Epub 2017 Apr 8. Muscle Nerve. 2017. PMID: 28073153
Frequently, both the root mean square of successive differences (RMSSD) and SD1, which is a Poincare plot component, have been used to quantify short-term heart rate variability. It is not typically appreciated, however, that RMSSD and SD1 are identical metrics of HRV. ...
Frequently, both the root mean square of successive differences (RMSSD) and SD1, which is a Poincare plot component, have been used to quant …
Compound risk of high mortality following osteoporotic fracture and refracture in elderly women and men.
Bliuc D, Nguyen ND, Nguyen TV, Eisman JA, Center JR. Bliuc D, et al. Among authors: nguyen nd. J Bone Miner Res. 2013 Nov;28(11):2317-24. doi: 10.1002/jbmr.1968. J Bone Miner Res. 2013. PMID: 23616397 Free article.
These outcomes, particularly premature mortality following refracture, have not previously been studied together to understand overall mortality risk. This study examined the long-term cumulative incidence of subsequent fracture and total mortality with mortality calculate …
These outcomes, particularly premature mortality following refracture, have not previously been studied together to understand overall morta …
Application of solution-processed metal oxide layers as charge transport layers for CdSe/ZnS quantum-dot LEDs.
Nguyen HT, Nguyen ND, Lee S. Nguyen HT, et al. Among authors: nguyen nd. Nanotechnology. 2013 Mar 22;24(11):115201. doi: 10.1088/0957-4484/24/11/115201. Epub 2013 Feb 28. Nanotechnology. 2013. PMID: 23449207
In addition to the control of the respective concentrations of holes and electrons within a multilayer device structure, which determines the luminance and efficiency of QLEDs, the use of metal oxide layers is advantageous for long-term stability of QLEDs because they are …
In addition to the control of the respective concentrations of holes and electrons within a multilayer device structure, which determines th …
Risk factors for in-hospital post-hip fracture mortality.
Frost SA, Nguyen ND, Black DA, Eisman JA, Nguyen TV. Frost SA, et al. Among authors: nguyen nd. Bone. 2011 Sep;49(3):553-8. doi: 10.1016/j.bone.2011.06.002. Epub 2011 Jun 13. Bone. 2011. PMID: 21689802
Using the identified risk factors, prognostic nomograms were developed for predicting short term risk of mortality for an individual. RESULTS: The median duration of hospitalization was 9 days. ...
Using the identified risk factors, prognostic nomograms were developed for predicting short term risk of mortality for an individual. …
18 results