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Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs.
Nauman G, Danzl NM, Lee J, Borsotti C, Madley R, Fu J, Hölzl MA, Dahmani A, Dorronsoro Gonzalez A, Chavez É, Campbell SR, Yang S, Satwani P, Liu K, Sykes M. Nauman G, et al. J Immunol. 2022 Apr 1;208(7):1652-1663. doi: 10.4049/jimmunol.2100966. Epub 2022 Mar 21. J Immunol. 2022. PMID: 35315788 Free PMC article.
The number of HSCs increased in PI mice compared with the originally infused BM cells and maintained functional repopulation potential, because BM from some PI mice 28 wk posttransplant generated human myeloid and lymphoid cells in secondary recipients. Moreover, long-term …
The number of HSCs increased in PI mice compared with the originally infused BM cells and maintained functional repopulation potential, beca …
Reduced positive selection of a human TCR in a swine thymus using a humanized mouse model for xenotolerance induction.
Nauman G, Borsotti C, Danzl N, Khosravi-Maharlooei M, Li HW, Chavez E, Stone S, Sykes M. Nauman G, et al. Xenotransplantation. 2020 Jan;27(1):e12558. doi: 10.1111/xen.12558. Epub 2019 Sep 29. Xenotransplantation. 2020. PMID: 31565822 Free PMC article.
BACKGROUND: Tolerance-inducing approaches to xenotransplantation would be optimal and may be necessary for long-term survival of transplanted pig organs in human patients. The ideal approach would generate donor-specific unresponsiveness to the pig organ without suppressin …
BACKGROUND: Tolerance-inducing approaches to xenotransplantation would be optimal and may be necessary for long-term survival of tran …