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Self-Reported Sleep Duration and Bedtime Are Associated with Dementia Risk in Community-Dwelling People Aged 40-74 Years: The Murakami Cohort Study.
Bulycheva I, Watanabe Y, Kitamura K, Kabasawa K, Saito T, Takahashi A, Kobayashi R, Oshiki R, Takachi R, Tsugane S, Yamazaki O, Watanabe K, Nakamura K. Bulycheva I, et al. Among authors: nakamura k. J Alzheimers Dis. 2024 Apr 26. doi: 10.3233/JAD-231104. Online ahead of print. J Alzheimers Dis. 2024. PMID: 38669530
Predictors were self-reported sleep duration and bedtime, and the outcome was newly-diagnosed dementia determined using the long-term care insurance database. Covariates were demographic characteristics, body mass index, smoking, alcohol consumption, total physical activit …
Predictors were self-reported sleep duration and bedtime, and the outcome was newly-diagnosed dementia determined using the long-term …
Cost-effectiveness analysis of abrocitinib compared with standard of care in adult moderate-to-severe atopic dermatitis in Japan.
Tanaka A, Yuasa A, Kamei K, Nagano M, Murofushi T, Bjerke A, Nakamura K, Ikeda S. Tanaka A, et al. Among authors: nakamura k. J Dermatol. 2024 Apr 22. doi: 10.1111/1346-8138.17234. Online ahead of print. J Dermatol. 2024. PMID: 38650307
A hybrid decision tree and Markov model were used to capture the initial treatment and long-term maintenance phases. Clinical inputs at 16 weeks were obtained through a Bayesian network meta-analysis of four pivotal trials from the JADE program. ...
A hybrid decision tree and Markov model were used to capture the initial treatment and long-term maintenance phases. Clinical inputs …
Long-term follow-up and exploratory analysis of lenvatinib in patients with metastatic or recurrent thymic carcinoma: Results from the multicenter, phase 2 REMORA trial.
Niho S, Sato J, Satouchi M, Itoh S, Okuma Y, Mizugaki H, Murakami H, Fujisaka Y, Kozuki T, Nakamura K, Machida R, Ohe Y, Tamai T, Ikezawa H, Yamamoto N. Niho S, et al. Among authors: nakamura k. Lung Cancer. 2024 Mar 30;191:107557. doi: 10.1016/j.lungcan.2024.107557. Online ahead of print. Lung Cancer. 2024. PMID: 38626709
OBJECTIVES: The main objective of this report was to detail the long-term follow-up data from the REMORA study, which investigated the safety and efficacy of lenvatinib in patients with thymic carcinoma. ...Forty-two patients received oral lenvatinib 24 mg once daily in 4- …
OBJECTIVES: The main objective of this report was to detail the long-term follow-up data from the REMORA study, which investigated th …
The MDM2-p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells.
Nakagawa-Saito Y, Mitobe Y, Togashi K, Suzuki S, Sugai A, Takenouchi S, Nakamura K, Sonoda Y, Kitanaka C, Okada M. Nakagawa-Saito Y, et al. Among authors: nakamura k. Int J Mol Sci. 2024 Apr 2;25(7):3948. doi: 10.3390/ijms25073948. Int J Mol Sci. 2024. PMID: 38612758 Free PMC article.
The prevention of tumor recurrence by the successful targeting of glioma stem cells endowed with a tumor-initiating capacity is deemed the key to the long-term survival of glioblastoma patients. Glioma stem cells are characterized by their marked therapeutic resistance; ho …
The prevention of tumor recurrence by the successful targeting of glioma stem cells endowed with a tumor-initiating capacity is deemed the k …
Milk-based culture of Penicillium camemberti and its component oleamide affect cognitive function in healthy elderly Japanese individuals: a multi-arm randomized, double-blind, placebo-controlled study.
Sasaki M, Oba C, Nakamura K, Takeo H, Toya H, Furuichi K. Sasaki M, et al. Among authors: nakamura k. Front Nutr. 2024 Mar 27;11:1357920. doi: 10.3389/fnut.2024.1357920. eCollection 2024. Front Nutr. 2024. PMID: 38600994 Free PMC article.
Our results suggest that MCW and its component, oleamide, are safe and contribute to maintaining cognitive functions, particularly short-term and working memory, and improving sleep state. Clinical trial registration: https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cg …
Our results suggest that MCW and its component, oleamide, are safe and contribute to maintaining cognitive functions, particularly short- …
Low plasma 25-hydroxyvitamin D levels are not associated with a high risk of recurrent falls in community-dwelling Japanese adults: the Murakami cohort study.
Nishikura T, Kitamura K, Watanabe Y, Kabasawa K, Saito T, Takahashi A, Takachi R, Kobayashi R, Oshiki R, Tsugane S, Watanabe K, Nakamura K. Nishikura T, et al. Among authors: nakamura k. Arch Osteoporos. 2024 Apr 3;19(1):25. doi: 10.1007/s11657-024-01381-8. Arch Osteoporos. 2024. PMID: 38568437
Reports on the association between vitamin D levels and fall risk have been mixed, and long-term follow-up studies are lacking. This 5-year cohort study of 5,343 community-dwelling Japanese people aged 40-74 years found that low vitamin D levels are not associated with a h …
Reports on the association between vitamin D levels and fall risk have been mixed, and long-term follow-up studies are lacking. This …
Rapid and long-lasting efficacy of high-dose ambroxol therapy for neuronopathic Gaucher disease: A case report and literature review.
Higashi K, Sonoda Y, Kaku N, Fujii F, Yamashita F, Lee S, Tocan V, Ebihara G, Matsuoka W, Tetsuhara K, Sonoda M, Chong PF, Mushimoto Y, Kojima-Ishii K, Ishimura M, Koga Y, Fukuta A, Tsuchihashi NA, Kikuchi Y, Karashima T, Sawada T, Hotta T, Yoshimitsu M, Terazono H, Tajiri T, Nakagawa T, Sakai Y, Nakamura K, Ohga S. Higashi K, et al. Among authors: nakamura k. Mol Genet Genomic Med. 2024 Apr;12(4):e2427. doi: 10.1002/mgg3.2427. Mol Genet Genomic Med. 2024. PMID: 38553911 Free PMC article. Review.
However, little is known about the clinical indication and the long-term outcome of patients after ambroxol therapy. We herein report a case of a female patient who presented with a progressive disease of GD type 2 from 11 months of age and had the pathogenic variants of p …
However, little is known about the clinical indication and the long-term outcome of patients after ambroxol therapy. We herein report …
Transitional dynamics in oncology clinical trials: evaluating the impact of Clinical Trials Act on cooperative groups.
Nakamura K, Takeda K, Saito AM, Kato M, Sato S, Nakagawa S, Kawamoto Y, Oki E, Okamoto I, Okamoto H, Katayama H, Mizusawa J, Kaba H, Shibata T, Fukuda H. Nakamura K, et al. Jpn J Clin Oncol. 2024 Mar 26:hyae034. doi: 10.1093/jjco/hyae034. Online ahead of print. Jpn J Clin Oncol. 2024. PMID: 38535873
The Clinical Trials Act was enforced on 1 April 2018, in Japan, and it has remarkably increased the operational burden on investigators, but its long-term impact on cancer cooperative groups is unknown. METHODS: a survey was conducted across the nine major cooperative grou …
The Clinical Trials Act was enforced on 1 April 2018, in Japan, and it has remarkably increased the operational burden on investigators, but …
Long-term, non-invasive FTIR detection of low-dose ionizing radiation exposure.
Inman JL, Wu Y, Chen L, Brydon E, Ghosh D, Wan KH, De Chant J, Obst-Huebl L, Nakamura K, Ralston CY, Celniker SE, Mao JH, Zwart PH, Holman HN, Chang H, Brown JB, Snijders AM. Inman JL, et al. Among authors: nakamura k. Sci Rep. 2024 Mar 13;14(1):6119. doi: 10.1038/s41598-024-56491-7. Sci Rep. 2024. PMID: 38480827 Free PMC article.
Post-intensive care syndrome: Recent advances and future directions.
Inoue S, Nakanishi N, Amaya F, Fujinami Y, Hatakeyama J, Hifumi T, Iida Y, Kawakami D, Kawai Y, Kondo Y, Liu K, Nakamura K, Nishida T, Sumita H, Taito S, Takaki S, Tsuboi N, Unoki T, Yoshino Y, Nishida O. Inoue S, et al. Among authors: nakamura k. Acute Med Surg. 2024 Feb 20;11(1):e929. doi: 10.1002/ams2.929. eCollection 2024 Jan-Dec. Acute Med Surg. 2024. PMID: 38385144 Free PMC article. Review.
It occurs either during the ICU stay or following ICU discharge and is related to the patients' long-term prognosis. The same concept also applies to pediatric patients, and it can greatly affect the mental status of family members. ...
It occurs either during the ICU stay or following ICU discharge and is related to the patients' long-term prognosis. The same concept …
648 results