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HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing.
Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O'Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M. Lyons DE, et al. Among authors: murthy n. Viruses. 2023 Oct 28;15(11):2171. doi: 10.3390/v15112171. Viruses. 2023. PMID: 38005849 Free PMC article.
We propose a novel "block-lock-stop" approach, entailing long term durable silencing of viral expression towards an irreversible transcriptionally inactive latent provirus to achieve long term antiretroviral free control of the virus. ...
We propose a novel "block-lock-stop" approach, entailing long term durable silencing of viral expression towards an irreversible tran …
Axonal Tract Reconstruction Using a Tissue-Engineered Nigrostriatal Pathway in a Rat Model of Parkinson's Disease.
Struzyna LA, Browne KD, Burrell JC, Vélez WJG, Wofford KL, Kaplan HM, Murthy NS, Chen HI, Duda JE, España RA, Cullen DK. Struzyna LA, et al. Among authors: murthy ns. Int J Mol Sci. 2022 Nov 12;23(22):13985. doi: 10.3390/ijms232213985. Int J Mol Sci. 2022. PMID: 36430464 Free PMC article.
This work showed proof of concept that TE-NSPs can reconstruct the nigrostriatal pathway, providing motivation for future studies evaluating potential functional benefits and long-term durability of this strategy. This pathway reconstruction strategy may ultimately replace …
This work showed proof of concept that TE-NSPs can reconstruct the nigrostriatal pathway, providing motivation for future studies evaluating …
COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022.
Havers FP, Pham H, Taylor CA, Whitaker M, Patel K, Anglin O, Kambhampati AK, Milucky J, Zell E, Moline HL, Chai SJ, Kirley PD, Alden NB, Armistead I, Yousey-Hindes K, Meek J, Openo KP, Anderson EJ, Reeg L, Kohrman A, Lynfield R, Como-Sabetti K, Davis EM, Cline C, Muse A, Barney G, Bushey S, Felsen CB, Billing LM, Shiltz E, Sutton M, Abdullah N, Talbot HK, Schaffner W, Hill M, George A, Hall AJ, Bialek SR, Murthy NC, Murthy BP, McMorrow M. Havers FP, et al. Among authors: murthy nc. JAMA Intern Med. 2022 Oct 1;182(10):1071-1081. doi: 10.1001/jamainternmed.2022.4299. JAMA Intern Med. 2022. PMID: 36074486 Free PMC article.
Hospitalized vaccinated persons were older and more likely to have 3 or more underlying medical conditions and be long-term care facility residents compared with hospitalized unvaccinated persons. ...
Hospitalized vaccinated persons were older and more likely to have 3 or more underlying medical conditions and be long-term care faci …
Drug utilization study in neonatal intensive care unit at tertiary care hospital.
Namdarifar F, Raouf S, Shahraki EM, Murthy NBS. Namdarifar F, et al. Among authors: murthy nbs. Rev Assoc Med Bras (1992). 2022 Feb;68(2):212-216. doi: 10.1590/1806-9282.20210831. Rev Assoc Med Bras (1992). 2022. PMID: 35239884 Free article.
RESULTS: Among the patients, 52% were males and 48% were females. Notably, 38% of patients were preterm, 60% were term, and only 2% were post-term. Also, 80.6% were born by cesarean section and 19.4% were born by normal vaginal delivery. ...There were some possible …
RESULTS: Among the patients, 52% were males and 48% were females. Notably, 38% of patients were preterm, 60% were term, and only 2% w …
An effective technique for diabetic retinopathy using hybrid machine learning technique.
Murthy NS, Arunadevi B. Murthy NS, et al. Stat Methods Med Res. 2021 Apr;30(4):1042-1056. doi: 10.1177/0962280220983541. Epub 2021 Jan 26. Stat Methods Med Res. 2021. PMID: 33499772
In the classification step, those segmented images are given as input to hybrid techniques such as a convolution neural network with bidirectional-long short-term memory (CNN with Bi-LSTM). The learning degree of Bi-LSTM is revised by using the self-attention mechanism for …
In the classification step, those segmented images are given as input to hybrid techniques such as a convolution neural network with bidirec …
Shoulder mechanical impingement risk associated with manual wheelchair tasks in individuals with spinal cord injury.
Mozingo JD, Akbari-Shandiz M, Murthy NS, Van Straaten MG, Schueler BA, Holmes DR 3rd, McCollough CH, Zhao KD. Mozingo JD, et al. Among authors: murthy ns. Clin Biomech (Bristol, Avon). 2020 Jan;71:221-229. doi: 10.1016/j.clinbiomech.2019.10.017. Epub 2019 Oct 20. Clin Biomech (Bristol, Avon). 2020. PMID: 32035338 Free PMC article.
Frequency of and technique used to complete daily tasks should be carefully considered to reduce impingement risk, which may help preserve shoulder health long-term....
Frequency of and technique used to complete daily tasks should be carefully considered to reduce impingement risk, which may help preserve s …
Liraglutide and Renal Outcomes in Type 2 Diabetes.
Mann JFE, Ørsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S, Tornøe K, Zinman B, Buse JB; LEADER Steering Committee and Investigators. Mann JFE, et al. N Engl J Med. 2017 Aug 31;377(9):839-848. doi: 10.1056/NEJMoa1616011. N Engl J Med. 2017. PMID: 28854085 Free article. Clinical Trial.
BACKGROUND: In a randomized, controlled trial that compared liraglutide, a glucagon-like peptide 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk who were receiving usual care, we found that liraglutide resulted in lower risks of the primary …
BACKGROUND: In a randomized, controlled trial that compared liraglutide, a glucagon-like peptide 1 analogue, with placebo in patients with t …
Carotid intimo-medial thickness: A predictor for cardiovascular disorder in patients with polycystic ovarian syndrome in the South Indian population.
Garg N, Dharmalingam M, Prabhu V, Murthy NS. Garg N, et al. Among authors: murthy ns. Indian J Endocrinol Metab. 2016 Sep-Oct;20(5):662-666. doi: 10.4103/2230-8210.190552. Indian J Endocrinol Metab. 2016. PMID: 27730077 Free PMC article.
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine problem, which is now recognized as not only a reproductive but also a metabolic disorder with long-term effects on women's health, it has a prevalence of 5-10% in India. ...
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine problem, which is now recognized as not only a reproductive but also a me …
Imaging and Clinical Characteristics Predict Near-Term Disablement From Bone Metastases: Implications for Rehabilitation.
Cheville AL, Murthy NS, Basford JR, Rose PS, Tran K, Pittelkow TP, Ringler MD. Cheville AL, et al. Among authors: murthy ns. Arch Phys Med Rehabil. 2016 Jan;97(1):53-60. doi: 10.1016/j.apmr.2015.09.011. Epub 2015 Oct 3. Arch Phys Med Rehabil. 2016. PMID: 26435301 Free PMC article.
OBJECTIVE: To distinguish which patients with bone metastases are at risk for near-term disablement in order to assist clinicians in assessing the appropriateness of referrals for rehabilitation services. ...While neither the number of bone metastases nor their specific lo …
OBJECTIVE: To distinguish which patients with bone metastases are at risk for near-term disablement in order to assist clinicians in …
23 results