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Admission ultrasonography as a means of identifying unrecognized fetal compromise in term singleton pregnancies at the onset of labor - a feasibility study.
Oduola O, Kennelly M, Murphy DJ. Oduola O, et al. Among authors: murphy dj. J Matern Fetal Neonatal Med. 2023 Dec;36(2):2241104. doi: 10.1080/14767058.2023.2241104. J Matern Fetal Neonatal Med. 2023. PMID: 37527967 Free article.
OBJECTIVES: Apparently uncomplicated low-risk pregnancies, especially first time births, account for a significant proportion of adverse birth outcomes. Improved risk stratification with a simple bedside scan on admission in early labor could potentially reduce adverse int …
OBJECTIVES: Apparently uncomplicated low-risk pregnancies, especially first time births, account for a significant proportion of adverse …
Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre-Heart Failure With Preserved Ejection Fraction: The PARABLE Randomized Clinical Trial.
Ledwidge M, Dodd JD, Ryan F, Sweeney C, McDonald K, Fox R, Shorten E, Zhou S, Watson C, Gallagher J, McVeigh N, Murphy DJ, McDonald K. Ledwidge M, et al. Among authors: murphy dj. JAMA Cardiol. 2023 Apr 1;8(4):366-375. doi: 10.1001/jamacardio.2023.0065. JAMA Cardiol. 2023. PMID: 36884247 Free PMC article. Clinical Trial.
More work is needed to understand the observed increased cardiac volumes and long-term effects of sacubitril/valsartan in patients with pre-HFpEF. ...
More work is needed to understand the observed increased cardiac volumes and long-term effects of sacubitril/valsartan in patients wi …
Pulmonary renal syndrome: a clinical review.
Boyle N, O'Callaghan M, Ataya A, Gupta N, Keane MP, Murphy DJ, McCarthy C. Boyle N, et al. Among authors: murphy dj. Breathe (Sheff). 2022 Dec;18(4):220208. doi: 10.1183/20734735.0208-2022. Epub 2023 Jan 10. Breathe (Sheff). 2022. PMID: 36865943 Free PMC article. Review.
The term "pulmonary renal syndrome" describes a clinical syndrome which is characterised by the presence of both diffuse alveolar haemorrhage and glomerulonephritis. ...
The term "pulmonary renal syndrome" describes a clinical syndrome which is characterised by the presence of both diffuse alveolar hae …
Fetal scalp stimulation for assessing fetal well-being during labour.
Murphy DJ, Devane D, Molloy E, Shahabuddin Y. Murphy DJ, et al. Cochrane Database Syst Rev. 2023 Jan 10;1(1):CD013808. doi: 10.1002/14651858.CD013808.pub2. Cochrane Database Syst Rev. 2023. PMID: 36625680 Free PMC article. Review.
The evidence was also very uncertain between dFSS and FBS for assisted vaginal birth (RR 1.44, 95% CI 0.76 to 2.75; very low-certainty evidence) and for the spontaneous vaginal birth rate (RR 2.33, 95% CI 0.68 to 8.01, very low-certainty evidence). ...There were no …
The evidence was also very uncertain between dFSS and FBS for assisted vaginal birth (RR 1.44, 95% CI 0.76 to 2.75; very low-certaint …
Digital fetal scalp stimulation (dFSS) versus fetal blood sampling (FBS) to assess fetal wellbeing in labour-a multi-centre randomised controlled trial: Fetal Intrapartum Randomised Scalp Stimulation Trial (FIRSST NCT05306756).
Murphy DJ, Shahabuddin Y, Yambasu S, O'Donoghue K, Devane D, Cotter A, Gaffney G, Burke LA, Molloy EJ, Boland F. Murphy DJ, et al. Trials. 2022 Oct 4;23(1):848. doi: 10.1186/s13063-022-06794-9. Trials. 2022. PMID: 36195894 Free PMC article. Clinical Trial.
METHODS: A multi-centre parallel group randomised controlled trial (RCT) is planned in four maternity centres in Ireland. The study aims to recruit 2500 nulliparous women with a term (37+0 weeks) singleton pregnancy who require a second-line test of fetal wellbeing in labo …
METHODS: A multi-centre parallel group randomised controlled trial (RCT) is planned in four maternity centres in Ireland. The study aims to …
Real-world efficacy of lutetium peptide receptor radionuclide therapy in patients with neuroendocrine tumours.
Almeamar H, Cullen L, Murphy DJ, Crowley RK, Toumpanakis C, Welin S, O'Shea D, O'Toole D. Almeamar H, et al. Among authors: murphy dj. J Neuroendocrinol. 2022 Jun;34(6):e13138. doi: 10.1111/jne.13138. Epub 2022 Apr 29. J Neuroendocrinol. 2022. PMID: 35485450
Here, we report a single centre experience of real-world efficacy, long-term side effects, and challenges of this treatment. This was a retrospective analysis. ...
Here, we report a single centre experience of real-world efficacy, long-term side effects, and challenges of this treatment. This was …
Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial.
Mackenzie IS, Ford I, Nuki G, Hallas J, Hawkey CJ, Webster J, Ralston SH, Walters M, Robertson M, De Caterina R, Findlay E, Perez-Ruiz F, McMurray JJV, MacDonald TM; FAST Study Group. Mackenzie IS, et al. Lancet. 2020 Nov 28;396(10264):1745-1757. doi: 10.1016/S0140-6736(20)32234-0. Epub 2020 Nov 9. Lancet. 2020. PMID: 33181081 Clinical Trial.
INTERPRETATION: Febuxostat is non-inferior to allopurinol therapy with respect to the primary cardiovascular endpoint, and its long-term use is not associated with an increased risk of death or serious adverse events compared with allopurinol. ...
INTERPRETATION: Febuxostat is non-inferior to allopurinol therapy with respect to the primary cardiovascular endpoint, and its long-term …
Membrane sweeping for induction of labour.
Finucane EM, Murphy DJ, Biesty LM, Gyte GM, Cotter AM, Ryan EM, Boulvain M, Devane D. Finucane EM, et al. Among authors: murphy dj. Cochrane Database Syst Rev. 2020 Feb 27;2(2):CD000451. doi: 10.1002/14651858.CD000451.pub3. Cochrane Database Syst Rev. 2020. PMID: 32103497 Free PMC article.
OBJECTIVES: To assess the effects and safety of membrane sweeping for induction of labour in women at or near term ( 36 weeks' gestation). SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register (25 February 2019), ClinicalTrials.gov, the WHO Intern …
OBJECTIVES: To assess the effects and safety of membrane sweeping for induction of labour in women at or near term ( 36 weeks' gestat …
Rotating-hinge knee prosthesis as a viable option in primary surgery: Literature review & meta-analysis.
Abdulkarim A, Keane A, Hu SY, Glen L, Murphy DJ. Abdulkarim A, et al. Among authors: murphy dj. Orthop Traumatol Surg Res. 2019 Nov;105(7):1351-1359. doi: 10.1016/j.otsr.2019.08.012. Epub 2019 Oct 3. Orthop Traumatol Surg Res. 2019. PMID: 31588033 Free article. Review.
RESULTS: We found that for certain indications the prosthesis has impressive survival rates and functional outcomes. Short-term (1-5 year) prosthesis survival in non-tumour cases was 92% (95% CI, 87-98%) and 77% (95% CI, 68-87%) in tumour cases. Mid-term (6-10 year) …
RESULTS: We found that for certain indications the prosthesis has impressive survival rates and functional outcomes. Short-term (1-5 …
Forceps delivery for non-rotational and rotational operative vaginal delivery.
Black M, Murphy DJ. Black M, et al. Among authors: murphy dj. Best Pract Res Clin Obstet Gynaecol. 2019 Apr;56:55-68. doi: 10.1016/j.bpobgyn.2019.02.002. Epub 2019 Feb 11. Best Pract Res Clin Obstet Gynaecol. 2019. PMID: 30827815 Review.
Maternal and offspring outcomes of forceps-assisted birth have been extensively reported in observational studies, but randomised trial evidence is limited. ...Second-stage caesarean section is associated with less foetal-neonatal trauma than forceps-assisted delivery but …
Maternal and offspring outcomes of forceps-assisted birth have been extensively reported in observational studies, but randomised tri …
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