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IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors.
Wang Y, Shimosaki S, Ikebe E, Iha H, Yamamoto JI, Fife N, Ichikawa T, Hori M, Ogata M, Tsukamoto Y, Hijiya N, Moriyama M, Hagiwara S, Kusano S, Saito M, Ahmed K, Nishizono A, Handa H, Morishita K. Wang Y, et al. Among authors: morishita k. Front Oncol. 2024 Jan 24;13:1272528. doi: 10.3389/fonc.2023.1272528. eCollection 2023. Front Oncol. 2024. PMID: 38344143 Free PMC article.
Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has been employed as an additional therapeutic option for ATL since 2017, but its mechanism of action has not been fully proven, and recent studies reported emerging concerns about the development of second prim …
Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has been employed as an additional therapeutic option for ATL since 201 …
Successful treatment of sclerosing encapsulating peritonitis in a cat using bioresorbable hyaluronate-carboxymethylcellulose membrane after surgical adhesiolysis and long-term prednisolone.
Yokoyama N, Kinoshita R, Ohta H, Okada K, Shimbo G, Sasaoka K, Nagata N, Sasaki N, Morishita K, Nakamura K, Kagawa Y, Takiguchi M. Yokoyama N, et al. Among authors: morishita k. JFMS Open Rep. 2023 Nov 24;9(2):20551169231209917. doi: 10.1177/20551169231209917. eCollection 2023 Jul-Dec. JFMS Open Rep. 2023. PMID: 38022706 Free PMC article.
Histopathologic findings of the peritoneal biopsy specimen confirmed SEP. Long-term prednisolone treatment (1 mg/kg for the first dose and 0.5 mg/kg every 48 h for maintenance) was administered postoperatively. ...RELEVANCE AND NOVEL INFORMATION: To our knowledge, this is …
Histopathologic findings of the peritoneal biopsy specimen confirmed SEP. Long-term prednisolone treatment (1 mg/kg for the first dos …
Risk factors for recurrence of suicide attempt via overdose: A prospective observational study.
Suekane A, Takayama W, Hashimoto R, Morishita K, Otomo Y. Suekane A, et al. Among authors: morishita k. Am J Emerg Med. 2024 Jan;75:1-6. doi: 10.1016/j.ajem.2023.10.016. Epub 2023 Oct 20. Am J Emerg Med. 2024. PMID: 37890336
CONCLUSIONS: A history of schizophrenia was an independent risk factor for the recurrence of overdose, and the presence of a cohabitant was significantly associated with a lower risk of recurrence. Large-scale, long-term studies are required to confirm the results of this …
CONCLUSIONS: A history of schizophrenia was an independent risk factor for the recurrence of overdose, and the presence of a cohabitant was …
Investigation of the therapeutic effects, predictors, and complications of long-term immunosuppressive therapy in dogs with precursor-targeted immune-mediated anemia.
Sugawara-Suda M, Morishita K, Iwanaga Y, Yamazaki J, Kagawa Y, Yokoyama N, Sasaki N, Ohta H, Nakamura K, Takiguchi M. Sugawara-Suda M, et al. Among authors: morishita k. J Vet Med Sci. 2023 Jul 1;85(7):695-701. doi: 10.1292/jvms.23-0010. Epub 2023 May 29. J Vet Med Sci. 2023. PMID: 37245993 Free PMC article.
Long-term effect of pulmonary rehabilitation in idiopathic pulmonary fibrosis: a randomised controlled trial.
Kataoka K, Nishiyama O, Ogura T, Mori Y, Kozu R, Arizono S, Tsuda T, Tomioka H, Tomii K, Sakamoto K, Ishimoto H, Kagajo M, Ito H, Ichikado K, Sasano H, Eda S, Arita M, Goto Y, Hataji O, Fuke S, Shintani R, Hasegawa H, Ando M, Ogawa T, Shiraishi M, Watanabe F, Nishimura K, Sasaki T, Miyazaki S, Saka H, Kondoh Y; FITNESS study Collaborators. Kataoka K, et al. Thorax. 2023 Aug;78(8):784-791. doi: 10.1136/thorax-2022-219792. Epub 2023 Apr 3. Thorax. 2023. PMID: 37012071 Clinical Trial.
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is characterised by worsening dyspnoea and exercise intolerance. RESEARCH QUESTION: Does a long-term pulmonary rehabilitation improve exercise tolerance in patients with IPF treated with standard antifibrotic drugs, which are …
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is characterised by worsening dyspnoea and exercise intolerance. RESEARCH QUESTION: Does a l …
Consensus Treatment Plans for Severe Pediatric Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Morishita KA, Wagner-Weiner L, Yen EY, Sivaraman V, James KE, Gerstbacher D, Szymanski AM, O'Neil KM, Cabral DA; Childhood Arthritis and Rheumatology Research Alliance (CARRA) Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Workgroup. Morishita KA, et al. Arthritis Care Res (Hoboken). 2022 Sep;74(9):1550-1558. doi: 10.1002/acr.24590. Epub 2022 Jun 1. Arthritis Care Res (Hoboken). 2022. PMID: 33675161 Review.
These CTPs were in principle accepted by CARRA-wide membership for the evaluation of pragmatic comparative effectiveness in a long-term registry....
These CTPs were in principle accepted by CARRA-wide membership for the evaluation of pragmatic comparative effectiveness in a long-term …
Pathophysiological significance of N-myc downstream-regulated gene 2 in cancer development through protein phosphatase 2A phosphorylation regulation.
Morishita K, Nakahata S, Ichikawa T. Morishita K, et al. Cancer Sci. 2021 Jan;112(1):22-30. doi: 10.1111/cas.14716. Epub 2020 Dec 3. Cancer Sci. 2021. PMID: 33128318 Free PMC article. Review.
Thus, NDRG2, as a PP2A adaptor, regulates the global phosphorylation of important signaling molecules. Moreover, the downregulation of NDRG2 expression by long-term stress-induced methylation is directly correlated with the development of ATLL and other cancers. ...
Thus, NDRG2, as a PP2A adaptor, regulates the global phosphorylation of important signaling molecules. Moreover, the downregulation of NDRG2 …
Soluble Low-density Lipoprotein Receptor-related Protein 1 in Juvenile Idiopathic Arthritis.
Rezaei E, Newkirk MM, Li Z, Gordon JR, Oen KG, Benseler SM, Boire G, Cabral DA, Campillo S, Chédeville G, Chetaille AL, Dancey P, Duffy C, Duffy KW, Houghton K, Huber AM, Jurencak R, Lang B, Morishita KA, Petty RE, Ramsey SE, Roth J, Schneider R, Scuccimarri R, Spiegel L, Stringer E, Tse SML, Tucker LB, Turvey SE, Yeung RSM, Rosenberg AM; Alan M. Rosenberg for the BBOP Study Group. Rezaei E, et al. Among authors: morishita ka. J Rheumatol. 2021 May;48(5):760-766. doi: 10.3899/jrheum.200391. Epub 2020 Oct 15. J Rheumatol. 2021. PMID: 33060303
CONCLUSION: Plasma sLRP1 levels correlate with clinical and biomarker indicators of short-term improvement in JIA disease activity, supporting sLRP1 as an upstream biomarker of potential utility for assessing JIA disease activity and outcome prediction....
CONCLUSION: Plasma sLRP1 levels correlate with clinical and biomarker indicators of short-term improvement in JIA disease activity, s …
Treatment Strategy of Endovascular versus Open Repair for Ruptured Abdominal Aortic Aneurysm Based on the Fitzgerald Classification.
Sato K, Kurimoto Y, Kuroda Y, Makino Y, Kubota S, Maruyama R, Hanawa M, Morishita K; Members of Hokkaido Society of Aortic Stent Graft Registry. Sato K, et al. Among authors: morishita k. Ann Vasc Surg. 2020 Nov;69:324-331. doi: 10.1016/j.avsg.2020.05.068. Epub 2020 Jun 4. Ann Vasc Surg. 2020. PMID: 32505681
We categorized these patients into Fitzgerald classes I and II (first category, n = 72) and classes III and IV (second category, n = 133). The short-term results of both EVAR and OR cases were examined in the 2 categories. ...
We categorized these patients into Fitzgerald classes I and II (first category, n = 72) and classes III and IV (second category, n = 133). T …
Long-term outcomes and disease course of children with juvenile idiopathic arthritis in the ReACCh-Out cohort: a two-centre experience.
Chhabra A, Robinson C, Houghton K, Cabral DA, Morishita K, Tucker LB, Petty RE, Larché M, Batthish M, Guzman J. Chhabra A, et al. Among authors: morishita k. Rheumatology (Oxford). 2020 Dec 1;59(12):3727-3730. doi: 10.1093/rheumatology/keaa118. Rheumatology (Oxford). 2020. PMID: 32402087 Free PMC article.
OBJECTIVE: To assess long-term outcomes of children with JIA diagnosed in the biologic era. ...
OBJECTIVE: To assess long-term outcomes of children with JIA diagnosed in the biologic era. ...
38 results