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Early Metabolic Endpoints Identify Persistent Treatment Efficacy in Recent-Onset Type 1 Diabetes Immunotherapy Trials.
Jacobsen LM, Cuthbertson D, Bundy BN, Atkinson MA, Moore W, Haller MJ, Russell WE, Gitelman SE, Herold KC, Redondo MJ, Sims EK, Wherrett DK, Moran A, Pugliese A, Gottlieb PA, Sosenko JM, Ismail HM; Type 1 Diabetes TrialNet Study Group. Jacobsen LM, et al. Among authors: moran a. Diabetes Care. 2024 Apr 15:dc240171. doi: 10.2337/dc24-0171. Online ahead of print. Diabetes Care. 2024. PMID: 38621411

The use of C-peptide AUC as a 6-month dynamic measure not only detected treatment efficacy but also suggested long-term C-peptide preservation (R2 for 12-month C-peptide AUC adjusted for age and baseline value was 0.80, P < 0.001), and this finding supported the concept

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The use of C-peptide AUC as a 6-month dynamic measure not only detected treatment efficacy but also suggested long-term C-peptide pre …
Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis.
Gómez Sánchez A, Colucci P, Moran A, Moya López A, Colligris B, Álvarez Y, Kennedy BN. Gómez Sánchez A, et al. Among authors: moran a. Open Res Eur. 2023 Nov 23;3:48. doi: 10.12688/openreseurope.15491.2. eCollection 2023. Open Res Eur. 2023. PMID: 38283058 Free PMC article.
However, there remains a knowledge gap in how constituents of cigarette smoke affect vision and retinal biology. We used zebrafish to assess effects of short-term acute exposure to cigarette smoke extract (CSE) on visual behaviour and retinal biology. ...
However, there remains a knowledge gap in how constituents of cigarette smoke affect vision and retinal biology. We used zebrafish to assess …
Effectiveness of Hypertension Management Strategies in SPRINT-Eligible US Adults: A Simulation Study.
Zhang F, Bryant KB, Moran AE, Zhang Y, Cohen JB, Bress AP, Sheppard JP, King JB, Derington CG, Weintraub WS, Kronish IM, Shea S, Bellows BK. Zhang F, et al. Among authors: moran ae. J Am Heart Assoc. 2024 Jan 16;13(2):e032370. doi: 10.1161/JAHA.123.032370. Epub 2024 Jan 12. J Am Heart Assoc. 2024. PMID: 38214272 Free PMC article.
BACKGROUND: Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long-term impac …
BACKGROUND: Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive …
Subthalamic nucleus physiology is correlated with deep brain stimulation motor and non-motor outcomes.
Levy M, Zurawel M, d'Hardemare V, Moran A, Andelman F, Manor Y, Cohen J, Meshulam M, Balash Y, Gurevich T, Fried I, Bergman H. Levy M, et al. Among authors: moran a. Brain Commun. 2023 Oct 18;5(6):fcad268. doi: 10.1093/braincomms/fcad268. eCollection 2023. Brain Commun. 2023. PMID: 38025270 Free PMC article.
However, there are no microelectrode recording-based tools with predictive values relating to long-term outcomes of integrative motor and non-motor symptoms. We conducted a retrospective analysis of the outcomes of patients with idiopathic Parkinson's disease who had subth …
However, there are no microelectrode recording-based tools with predictive values relating to long-term outcomes of integrative motor …
Impact of Hematopoietic Cell Transplantation on Cardiovascular Risk Factors and Insulin Sensitivity.
Ketterl TG, Chow EJ, Koves IH, Goodman P, Leisenring WM, Ballard S, Dengel DR, Moran A, Sinaiko AR, Steinberger J, Baker KS. Ketterl TG, et al. Among authors: moran a. Transplant Cell Ther. 2024 Feb;30(2):243.e1-243.e13. doi: 10.1016/j.jtct.2023.10.026. Epub 2023 Nov 5. Transplant Cell Ther. 2024. PMID: 37935316
The use of hematopoietic cell transplantation (HCT) for treating malignant conditions in children has increased over the past five decades, leading to a growing population of long-term survivors.This population of childhood HCT survivors faces increased risks of adverse me …
The use of hematopoietic cell transplantation (HCT) for treating malignant conditions in children has increased over the past five decades, …
The impact of the federal menu labeling law on the sentiment of Twitter discussions about restaurants and food retailers: An interrupted time series analysis.
Hswen Y, Moran AJ, von Ash T, Prasad S, Martheswaran T, Simon D, Cleveland LP, Brownstein JS, Block JP. Hswen Y, et al. Among authors: moran aj. Prev Med Rep. 2023 Oct 14;36:102478. doi: 10.1016/j.pmedr.2023.102478. eCollection 2023 Dec. Prev Med Rep. 2023. PMID: 37927975 Free PMC article.
Calorie labeling did not have a strong effect on the public's perception of food brands over the long-term on Twitter and may imply the need for greater efforts to change the sentiment towards unhealthy restaurant chains....
Calorie labeling did not have a strong effect on the public's perception of food brands over the long-term on Twitter and may imply t …
National, regional, and global estimates of preterm birth in 2020, with trends from 2010: a systematic analysis.
Ohuma EO, Moller AB, Bradley E, Chakwera S, Hussain-Alkhateeb L, Lewin A, Okwaraji YB, Mahanani WR, Johansson EW, Lavin T, Fernandez DE, Domínguez GG, de Costa A, Cresswell JA, Krasevec J, Lawn JE, Blencowe H, Requejo J, Moran AC. Ohuma EO, et al. Among authors: moran ac. Lancet. 2023 Oct 7;402(10409):1261-1271. doi: 10.1016/S0140-6736(23)00878-4. Lancet. 2023. PMID: 37805217 Free article.
BACKGROUND: Preterm birth is the leading cause of neonatal mortality and is associated with long-term physical, neurodevelopmental, and socioeconomic effects. ...Countries need to prioritise programmatic investments to prevent preterm birth and to ensure evid …
BACKGROUND: Preterm birth is the leading cause of neonatal mortality and is associated with long-term physical, neurodevelopme …
Association Between Acute Myocardial Infarction and Cognition.
Johansen MC, Ye W, Gross A, Gottesman RF, Han D, Whitney R, Briceño EM, Giordani BJ, Shore S, Elkind MSV, Manly JJ, Sacco RL, Fohner A, Griswold M, Psaty BM, Sidney S, Sussman J, Yaffe K, Moran AE, Heckbert S, Hughes TM, Galecki A, Levine DA. Johansen MC, et al. Among authors: moran ae. JAMA Neurol. 2023 Jul 1;80(7):723-731. doi: 10.1001/jamaneurol.2023.1331. JAMA Neurol. 2023. PMID: 37252710
The interaction analysis suggested that race and sex modified the degree of change in the decline in global cognition after MI (race post-MI slope interaction term, P = .02; sex post-MI slope interaction term, P = .04), with a smaller change in the decline over the …
The interaction analysis suggested that race and sex modified the degree of change in the decline in global cognition after MI (race post-MI …
Brain white-matter changes associated with symptomatic acute COVID-19 infection in the neonatal period.
Cromb D, Finck T, Quirke M, Cawley P, Moran A, Banjoko O, Rutherford MA, Arichi T. Cromb D, et al. Among authors: moran a. IDCases. 2023 May 8;32:e01796. doi: 10.1016/j.idcr.2023.e01796. eCollection 2023. IDCases. 2023. PMID: 37193002 Free PMC article.
We report an important case of periventricular white matter damage in a 1-month-old infant, demonstrated on high quality structural (T2) and diffusion weighted magnetic resonance imaging. The infant was born at term following an uneventful pregnancy and discharged home sho …
We report an important case of periventricular white matter damage in a 1-month-old infant, demonstrated on high quality structural (T2) and …
85 results