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Introduction of Tau Oligomers into Cortical Neurons Alters Action Potential Dynamics and Disrupts Synaptic Transmission and Plasticity.
eNeuro. 2019 Oct 15;6(5):ENEURO.0166-19.2019. doi: 10.1523/ENEURO.0166-19.2019. Print 2019 Sep/Oct.
eNeuro. 2019.
PMID: 31554666
Free PMC article.
Here, whole-cell patch clamp recording was used to introduce known concentrations of oligomeric full-length tau-441 into mouse hippocampal CA1 pyramidal and neocortical Layer V thick-tufted pyramidal cells. oTau increased input resistance, reduced action potential amplitude and s …
Here, whole-cell patch clamp recording was used to introduce known concentrations of oligomeric full-length tau-441 into mouse hippocampal C …
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