Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis.
Mobbs CV, Isoda F, Makimura H, Mastaitis J, Mizuno T, Shu IW, Yen K, Yang XJ.
Mobbs CV, et al.
Physiol Behav. 2005 May 19;85(1):3-23. doi: 10.1016/j.physbeh.2005.04.005.
Physiol Behav. 2005.
PMID: 15924903
Review.
Since leptin is not a physiological satiety factor (because it does not increase before meal termination), yet leptin deficiency causes obesity, we suggest that the glucostatic hypothesis be re-formulated without reference to satiety (i.e., short-term effects on food intak …
Since leptin is not a physiological satiety factor (because it does not increase before meal termination), yet leptin deficiency causes obes …