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Merkel cell carcinoma: long-term follow-up of a single institution series and clinical outcomes by immunological status.
Dasanu CA, Del Rosario M, Codreanu I, Lu Y, Farrell S, Hyams DM, Plaxe SC. Dasanu CA, et al. Dermatol Online J. 2019 Feb 15;25(2):13030/qt7697x76f. Dermatol Online J. 2019. PMID: 30865403 Free article.
Merkel cell carcinoma (MCC) usually arises in sun-exposed areas of older patients and might be more aggressive in the immunocompromised. ...
Merkel cell carcinoma (MCC) usually arises in sun-exposed areas of older patients and might be more aggressive in the immunocompromis …
Evidence-based medicine: facial skin malignancy.
Iorio ML, Ter Louw RP, Kauffman CL, Davison SP. Iorio ML, et al. Plast Reconstr Surg. 2013 Dec;132(6):1631-1643. doi: 10.1097/PRS.0b013e3182a8085f. Plast Reconstr Surg. 2013. PMID: 24281589 Review.
Timely diagnosis and treatment are critical for preventing continued spread and metastasis, and it is incumbent on the treating physician to make the appropriate recommendations for surgical margin and the possibility of adjuvant therapy to prevent recurrence and optimize long- …
Timely diagnosis and treatment are critical for preventing continued spread and metastasis, and it is incumbent on the treating physician to …
Long-term response to avelumab and management of oligoprogression in Merkel cell carcinoma: A case report.
Leão I, Marinho J, Costa T. Leão I, et al. World J Clin Cases. 2021 Jun 26;9(18):4829-4836. doi: 10.12998/wjcc.v9.i18.4829. World J Clin Cases. 2021. PMID: 34222455 Free PMC article.
BACKGROUND: Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neuroendocrine neoplasia, with high risk of recurrence and metastasis and poor survival. ...More than 2.5 years after surgery (last 19 mo without systemic therapy), the patient maintains complete lo …
BACKGROUND: Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neuroendocrine neoplasia, with high risk of recurrence and …
[What's new in dermato-oncology?].
Basset-Séguin N. Basset-Séguin N. Ann Dermatol Venereol. 2011 Dec;138 Suppl 4:S253-62. doi: 10.1016/S0151-9638(11)70099-0. Ann Dermatol Venereol. 2011. PMID: 22202647 Review. French.
PEG-interferon seems to be indicated in ulcerated melanoma with lymph node micrometastasis. Some other targeted molecules such as C-KIT and anti-MEK are under evaluation. The effect of sunscreens on melanoma risk prevention has been reported in an Australian study. ...Reco …
PEG-interferon seems to be indicated in ulcerated melanoma with lymph node micrometastasis. Some other targeted molecules such as C-K …
Advanced Merkel cell carcinoma of the lower extremity treated with surgery and isolated pelvic and limb perfusion using Melphalan: A case of unexpected long-term survival.
Guadagni S, Chiominto A, Mackay AR, Farina AR, Cappabianca L, Puccica I, Valiyeva S, Clementi M. Guadagni S, et al. Int J Surg Case Rep. 2019;61:4-8. doi: 10.1016/j.ijscr.2019.06.064. Epub 2019 Jul 8. Int J Surg Case Rep. 2019. PMID: 31302319 Free PMC article.
INTRODUCTION: Merkel cell carcinoma (MCC) is a rare, neuroendocrine skin tumor, with high frequency of locoregional recurrence, metastases, and poor prognosis. ...CONCLUSION: In this case, surgery combined with locoregional Melphalan chemotherapy was an effective and repea …
INTRODUCTION: Merkel cell carcinoma (MCC) is a rare, neuroendocrine skin tumor, with high frequency of locoregional recurrence, metas …
Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe.
Belmatoug N, Di Rocco M, Fraga C, Giraldo P, Hughes D, Lukina E, Maison-Blanche P, Merkel M, Niederau C, Plӧckinger U, Richter J, Stulnig TM, Vom Dahl S, Cox TM. Belmatoug N, et al. Eur J Intern Med. 2017 Jan;37:25-32. doi: 10.1016/j.ejim.2016.07.011. Epub 2016 Aug 10. Eur J Intern Med. 2017. PMID: 27522145 Free article. Review.
The therapeutic response to eliglustat and use of concomitant medications will require long-term monitoring....
The therapeutic response to eliglustat and use of concomitant medications will require long-term monitoring....
Siderite-based anaerobic iron cycle driven by autotrophic thermophilic microbial consortium.
Zavarzina DG, Kochetkova TV, Chistyakova NI, Gracheva MA, Antonova AV, Merkel AY, Perevalova AA, Chernov MS, Koksharov YA, Bonch-Osmolovskaya EA, Gavrilov SN, Bychkov AY. Zavarzina DG, et al. Sci Rep. 2020 Dec 10;10(1):21661. doi: 10.1038/s41598-020-78605-7. Sci Rep. 2020. PMID: 33303863 Free PMC article.
Using a sample from a terrestrial hot spring (pH 6.8, 60 C), we enriched a thermophilic microbial consortium performing anaerobic autotrophic oxidation of hydrothermal siderite (FeCO(3)), with CO(2)/bicarbonate as the electron acceptor and the only carbon source, producing …
Using a sample from a terrestrial hot spring (pH 6.8, 60 C), we enriched a thermophilic microbial consortium performing anaerobic aut …
Avelumab treatment in Italian patients with metastatic Merkel cell carcinoma: experience from an expanded access program.
Grignani G, Chiarion Sileni V, Pinto C, Depenni R, Fazio N, Galli L, Giuffrida D, Carnaghi C, Ciliberto D, Corsi DC, Queirolo P, Benincasa E, Venturini F, Fazzi G, Costa N, Ascierto PA. Grignani G, et al. J Transl Med. 2021 Feb 15;19(1):70. doi: 10.1186/s12967-021-02730-8. J Transl Med. 2021. PMID: 33588870 Free PMC article.
BACKGROUND: The incidence of Merkel cell carcinoma (MCC), a rare form of skin cancer with a poor prognosis, has increased in Italy in recent decades. ...The most frequently reported treatment-related adverse events were infusion-related reaction (single preferred term …
BACKGROUND: The incidence of Merkel cell carcinoma (MCC), a rare form of skin cancer with a poor prognosis, has increased in Italy in …
Long-term clinical outcome after beta-interferon therapy in cirrhotic patients with chronic hepatitis C. TVVH Study Group.
Bernardinello E, Cavalletto L, Chemello L, Mezzocolli I, Donada C, Benvegnú L, Merkel C, Gatta A, Alberti A. Bernardinello E, et al. Hepatogastroenterology. 1999 Nov-Dec;46(30):3216-22. Hepatogastroenterology. 1999. PMID: 10626189 Clinical Trial.
BACKGROUND/AIMS: Few data are available concerning the short and long-term effects of beta-IFN in patients with chronic hepatitis C. METHODOLOGY: We randomized 61 consecutive patients with HCV-related cirrhosis to receive: a) natural beta-IFN with a 6 MU/tiw for 6 m …
BACKGROUND/AIMS: Few data are available concerning the short and long-term effects of beta-IFN in patients with chronic hepatitis …
Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis.
Rodriguez-Pla A, Warner RL, Cuthbertson D, Carette S, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Ytterberg SR, Johnson KJ, Merkel PA, Monach PA; Vasculitis Clinical Research Consortium. Rodriguez-Pla A, et al. J Rheumatol. 2020 Jul 1;47(7):1001-1010. doi: 10.3899/jrheum.190093. Epub 2019 Sep 1. J Rheumatol. 2020. PMID: 31474593 Free PMC article.
Further studies are needed to determine whether these serum proteins have potential for clinical use in distinguishing active disease from remission or in predicting longer-term outcomes....
Further studies are needed to determine whether these serum proteins have potential for clinical use in distinguishing active disease from r …
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