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Leptin as predictor of cardiovascular events and high platelet reactivity in patients undergoing percutaneous coronary intervention.
Ricottini E, Gatto L, Nusca A, Melfi R, Mangiacapra F, Albano M, Cavallaro C, Pozzilli P, Di Sciascio G, Prati F, Ussia GP, Grigioni F. Ricottini E, et al. Among authors: melfi r. Clin Nutr ESPEN. 2023 Dec;58:104-110. doi: 10.1016/j.clnesp.2023.09.003. Epub 2023 Sep 22. Clin Nutr ESPEN. 2023. PMID: 38056992
The primary endpoint was the incidence of Major Acute Cardiac Events (MACE) at long-term follow-up according to leptin groups. Secondary endpoints were the evaluation of leptin levels according to PR groups and the incidence of periprocedural myocardial infarction (PMI) ac …
The primary endpoint was the incidence of Major Acute Cardiac Events (MACE) at long-term follow-up according to leptin groups. Second …
Relationship Between the Completeness of Revascularization and Myocardial Injury in Patients Treated With Percutaneous Coronary Intervention.
Paolucci L, Mangiacapra F, Viscusi MM, Ungaro S, Cocchia F, Piccirillo F, Nusca A, Melfi R, Ricottini E, Gallo P, Cocco N, Rinaldi R, Ussia GP, Grigioni F. Paolucci L, et al. Among authors: melfi r. Cardiovasc Revasc Med. 2023 Mar;48:15-20. doi: 10.1016/j.carrev.2022.10.006. Epub 2022 Oct 19. Cardiovasc Revasc Med. 2023. PMID: 36302704
OBJECTIVE: To investigate the relationship between different thresholds of post-PCI cardiac troponin (cTn) elevation and revascularization completeness in determining long-term clinical outcomes. METHODS: Patients were stratified in tertiles according to preprocedural SYNT …
OBJECTIVE: To investigate the relationship between different thresholds of post-PCI cardiac troponin (cTn) elevation and revascularization c …
Contrast-induced Acute Kidney Injury in Diabetic Patients and SGLT-2 Inhibitors: A Preventive Opportunity or Promoting Element?
Nusca A, Piccirillo F, Viscusi MM, Giannone S, Mangiacapra F, Melfi R, Ricottini E, Ussia GP, Grigioni F. Nusca A, et al. Among authors: melfi r. J Cardiovasc Pharmacol. 2022 Nov 1;80(5):661-671. doi: 10.1097/FJC.0000000000001329. J Cardiovasc Pharmacol. 2022. PMID: 35881892 Review.
Contrast-induced acute kidney injury (CI-AKI) is a serious complication in patients undergoing diagnostic or therapeutic procedures that require contrast use and negatively affects the long-term outcomes. Patients with type 2 diabetes mellitus (DM), particularly those who …
Contrast-induced acute kidney injury (CI-AKI) is a serious complication in patients undergoing diagnostic or therapeutic procedures that req …
Glycaemic Control in Patients Undergoing Percutaneous Coronary Intervention: What Is the Role for the Novel Antidiabetic Agents? A Comprehensive Review of Basic Science and Clinical Data.
Nusca A, Piccirillo F, Bernardini F, De Filippis A, Coletti F, Mangiacapra F, Ricottini E, Melfi R, Gallo P, Cammalleri V, Napoli N, Ussia GP, Grigioni F. Nusca A, et al. Among authors: melfi r. Int J Mol Sci. 2022 Jun 30;23(13):7261. doi: 10.3390/ijms23137261. Int J Mol Sci. 2022. PMID: 35806265 Free PMC article. Review.
In this setting, poor glycaemic control, regardless of diabetes, has been associated with increased incidence of peri-procedural and long-term complications and worse prognosis. Novel antidiabetic agents have represented a paradigm shift in managing patients with diabetes …
In this setting, poor glycaemic control, regardless of diabetes, has been associated with increased incidence of peri-procedural and long- …
Prediction of type 4a myocardial infarction with the angiography-derived hemodynamic (ADDED) index.
Mangiacapra F, Rinaldi R, Colaiori I, Sticchi A, Viscusi MM, Paolucci L, Russo M, Nusca A, Melfi R, Ricottini E, Gallo P, Ussia GP, Grigioni F. Mangiacapra F, et al. Among authors: melfi r. Heart Vessels. 2022 Sep;37(9):1471-1477. doi: 10.1007/s00380-022-02050-x. Epub 2022 Mar 12. Heart Vessels. 2022. PMID: 35279743
Whether a selective use of additional preventive measures in patients considered at high risk based on ADDED index values may improve peri-procedural and long-term outcomes remains to be tested in dedicated investigations....
Whether a selective use of additional preventive measures in patients considered at high risk based on ADDED index values may improve peri-p …
Ranolazine Improves Glycemic Variability and Endothelial Function in Patients with Diabetes and Chronic Coronary Syndromes: Results from an Experimental Study.
Nusca A, Bernardini F, Mangiacapra F, Maddaloni E, Melfi R, Ricottini E, Piccirillo F, Manfrini S, Ussia GP, Grigioni F. Nusca A, et al. Among authors: melfi r. J Diabetes Res. 2021 Dec 31;2021:4952447. doi: 10.1155/2021/4952447. eCollection 2021. J Diabetes Res. 2021. PMID: 35005029 Free PMC article.
Glucose-lowering and endothelial effects have also been reported with this agent. However, whether ranolazine may improve short-term glycemic variability (GV), strictly related to the prognosis of patients with type 2 diabetes (T2D), is unknown. Thus, we aimed to explore t …
Glucose-lowering and endothelial effects have also been reported with this agent. However, whether ranolazine may improve short-term
Antithrombotic treatment in patients with atrial fibrillation undergoing coronary angioplasty: rational convincement and supporting evidence.
Ricottini E, Nenna A, Melfi R, Giannone S, Lusini M, Sciascio GD, Chello M, Ussia GP, Grigioni F. Ricottini E, et al. Among authors: melfi r. Eur J Intern Med. 2020 Jul;77:44-51. doi: 10.1016/j.ejim.2020.02.004. Epub 2020 Feb 13. Eur J Intern Med. 2020. PMID: 32063489 Review.
BACKGROUND: The management of antithrombotic therapy in patients undergoing percutaneous coronary intervention (PCI) with an indication for long-term oral anticoagulant therapy (OAT) is still a matter of debate. ...Six randomized trials with 12,156 patients evaluating the …
BACKGROUND: The management of antithrombotic therapy in patients undergoing percutaneous coronary intervention (PCI) with an indication for …
Efficacy and Safety of Paclitaxel-Coated Balloon for the Treatment of In-Stent Restenosis in High-Risk Patients.
Miglionico M, Mangiacapra F, Nusca A, Scordino D, Gallo P, Campanale M, Melfi R, Di Sciascio G. Miglionico M, et al. Among authors: melfi r. Am J Cardiol. 2015 Dec 1;116(11):1690-4. doi: 10.1016/j.amjcard.2015.08.041. Epub 2015 Sep 10. Am J Cardiol. 2015. PMID: 26428021
In conclusion, the use of paclitaxel-coated balloon seems to be associated with favorable outcomes after percutaneous coronary intervention for BMS-ISR or DES-ISR in patients with high-risk clinical features and could be considered as a reasonable option in the presence of system …
In conclusion, the use of paclitaxel-coated balloon seems to be associated with favorable outcomes after percutaneous coronary intervention …
Glycemic Variability Assessed by Continuous Glucose Monitoring and Short-Term Outcome in Diabetic Patients Undergoing Percutaneous Coronary Intervention: An Observational Pilot Study.
Nusca A, Lauria Pantano A, Melfi R, Proscia C, Maddaloni E, Contuzzi R, Mangiacapra F, Palermo A, Manfrini S, Pozzilli P, Di Sciascio G. Nusca A, et al. Among authors: melfi r. J Diabetes Res. 2015;2015:250201. doi: 10.1155/2015/250201. Epub 2015 Jul 26. J Diabetes Res. 2015. PMID: 26273664 Free PMC article.
Strategies of clopidogrel load and atorvastatin reload to prevent ischemic cerebral events in patients undergoing protected carotid stenting. Results of the randomized ARMYDA-9 CAROTID (Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting) study.
Patti G, Tomai F, Melfi R, Ricottini E, Macrì M, Sedati P, Giardina A, Aurigemma C, Leporace M, D'Ambrosio A, Di Sciascio G. Patti G, et al. Among authors: melfi r. J Am Coll Cardiol. 2013 Apr 2;61(13):1379-87. doi: 10.1016/j.jacc.2013.01.015. Epub 2013 Mar 9. J Am Coll Cardiol. 2013. PMID: 23490041 Free article. Clinical Trial.
OBJECTIVES: This study sought to evaluate whether a strategy with a 600-mg clopidogrel load and a short-term, high-dose atorvastatin reload would improve outcomes in clopidogrel-naive, statin-treated patients undergoing protected carotid stenting. ...CONCLUSIONS: In patien …
OBJECTIVES: This study sought to evaluate whether a strategy with a 600-mg clopidogrel load and a short-term, high-dose atorvastatin …
14 results