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Introduction: Obesity and reproduction.
Meldrum DR. Meldrum DR. Fertil Steril. 2017 Apr;107(4):831-832. doi: 10.1016/j.fertnstert.2017.02.110. Fertil Steril. 2017. PMID: 28366410 Free article.
Such fundamental changes toward a healthier lifestyle will achieve steady and sustainable weight loss and long-term benefits for general health. The role of bariatric surgery before pregnancy requires careful consideration....
Such fundamental changes toward a healthier lifestyle will achieve steady and sustainable weight loss and long-term benefits for gene …
Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health.
Dumesic DA, Meldrum DR, Katz-Jaffe MG, Krisher RL, Schoolcraft WB. Dumesic DA, et al. Among authors: meldrum dr. Fertil Steril. 2015 Feb;103(2):303-16. doi: 10.1016/j.fertnstert.2014.11.015. Epub 2014 Dec 10. Fertil Steril. 2015. PMID: 25497448 Free article. Review.
Such intercellular communications allow the oocyte to determine its own fate by influencing the intrafollicular microenvironment, which in turn provides the necessary cellular functions for oocyte developmental competence, which is defined as the ability of the oocyte to complete …
Such intercellular communications allow the oocyte to determine its own fate by influencing the intrafollicular microenvironment, which in t …
Therapeutic applications of mesenchymal stem cells to repair kidney injury.
Asanuma H, Meldrum DR, Meldrum KK. Asanuma H, et al. Among authors: meldrum dr. J Urol. 2010 Jul;184(1):26-33. doi: 10.1016/j.juro.2010.03.050. Epub 2010 May 15. J Urol. 2010. PMID: 20478602 Review.
Multiple questions remain unanswered regarding the protective action of mesenchymal stem cells during renal injury, including signals that regulate stem cell homing to injured tissue, factors regulating paracrine and/or endocrine activity of exogenous mesenchymal stem cells and p …
Multiple questions remain unanswered regarding the protective action of mesenchymal stem cells during renal injury, including signals that r …
High glucose concentration in cell culture medium does not acutely affect human mesenchymal stem cell growth factor production or proliferation.
Weil BR, Abarbanell AM, Herrmann JL, Wang Y, Meldrum DR. Weil BR, et al. Among authors: meldrum dr. Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1735-43. doi: 10.1152/ajpregu.90876.2008. Epub 2009 Apr 22. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19386985 Free PMC article.
Contrary to what has been observed with other cells, hMSCs may be resistant to the short-term effects of high glucose. Ongoing efforts to characterize and optimize ex vivo and in vivo conditions are critical if the therapeutic benefits of MSCs are to be maximized....
Contrary to what has been observed with other cells, hMSCs may be resistant to the short-term effects of high glucose. Ongoing effort …
Oral sulfonylurea hypoglycemic agents prevent ischemic preconditioning in human myocardium. Two paradoxes revisited.
Cleveland JC Jr, Meldrum DR, Cain BS, Banerjee A, Harken AH. Cleveland JC Jr, et al. Among authors: meldrum dr. Circulation. 1997 Jul 1;96(1):29-32. doi: 10.1161/01.cir.96.1.29. Circulation. 1997. PMID: 9236412
CONCLUSIONS: Human myocardium from patients without long-term exposure to oral hypoglycemic agents is functionally protected by preconditioning. Long-term oral hypoglycemic intake blocks the protection by preconditioning. ...
CONCLUSIONS: Human myocardium from patients without long-term exposure to oral hypoglycemic agents is functionally protected by preco …
Pituitary function before, during, and after chronic gonadotropin-releasing hormone agonist therapy.
Cedars MI, Steingold KA, Lu JH, Judd HJ, Meldrum DR. Cedars MI, et al. Among authors: meldrum dr. Fertil Steril. 1992 Dec;58(6):1104-7. doi: 10.1016/s0015-0282(16)55551-4. Fertil Steril. 1992. PMID: 1459255 Free article.
OBJECTIVE: To examine possible adverse effects on pituitary function of long-term administration of gonadotropin-releasing hormone agonist (GnRH-a). ...CONCLUSIONS: Utilizing dynamic pituitary function tests, we were unable to demonstrate an adverse effect of long-term …
OBJECTIVE: To examine possible adverse effects on pituitary function of long-term administration of gonadotropin-releasing hormone ag …
Clinical and hormonal effects of chronic gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease.
Steingold K, De Ziegler D, Cedars M, Meldrum DR, Lu JK, Judd HL, Chang RJ. Steingold K, et al. Among authors: meldrum dr. J Clin Endocrinol Metab. 1987 Oct;65(4):773-8. doi: 10.1210/jcem-65-4-773. J Clin Endocrinol Metab. 1987. PMID: 3116031
Previously, we reported that short term administration of a highly potent GnRH agonist (GnRHa) for 1 month to patients with polycystic ovarian disease (PCO) resulted in complete suppression of ovarian steroidogenesis without measurable effects on adrenal steroid production …
Previously, we reported that short term administration of a highly potent GnRH agonist (GnRHa) for 1 month to patients with polycysti …
Estrogen replacement therapy: indications and complications.
Judd HL, Meldrum DR, Deftos LJ, Henderson BE. Judd HL, et al. Among authors: meldrum dr. Ann Intern Med. 1983 Feb;98(2):195-205. doi: 10.7326/0003-4819-98-2-195. Ann Intern Med. 1983. PMID: 6824255
Most investigations have failed to show the presence of estrogen receptors in bone. It is likely that the term osteoporosis includes heterogeneous skeletal disorders and that both sex hormones and calcemic hormones are important in pathogenesis. ...
Most investigations have failed to show the presence of estrogen receptors in bone. It is likely that the term osteoporosis includes …
Effect of megestrol acetate on flushing and bone metabolism in post-menopausal women.
Erlik Y, Meldrum DR, Lagasse LD, Judd HL. Erlik Y, et al. Among authors: meldrum dr. Maturitas. 1981 Aug;3(2):167-72. doi: 10.1016/0378-5122(81)90008-6. Maturitas. 1981. PMID: 7289887
Definitive demonstration of an effect on post-menopausal bone resorption will require a long-term study of bone density....
Definitive demonstration of an effect on post-menopausal bone resorption will require a long-term study of bone density....