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Prognostication in critically ill patients with severe traumatic brain injury: the TBI-Prognosis multicentre feasibility study.
Turgeon AF, Lauzier F, Zarychanski R, Fergusson DA, Léger C, McIntyre LA, Bernard F, Rigamonti A, Burns K, Griesdale DE, Green R, Scales DC, Meade MO, Savard M, Shemilt M, Paquet J, Gariépy JL, Lavoie A, Reddy K, Jichici D, Pagliarello G, Zygun D, Moore L; TBI-Prognosis Study Team and the Canadian Critical Care Trials Group. Turgeon AF, et al. Among authors: meade mo. BMJ Open. 2017 Apr 17;7(4):e013779. doi: 10.1136/bmjopen-2016-013779. BMJ Open. 2017. PMID: 28416497 Free PMC article.
OBJECTIVE: Severe traumatic brain injury is a significant cause of morbidity and mortality in young adults. Assessing long-term neurological outcome after such injury is difficult and often characterised by uncertainty. The objective of this feasibility study was to establ …
OBJECTIVE: Severe traumatic brain injury is a significant cause of morbidity and mortality in young adults. Assessing long-term neuro …
Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials.
Alhazzani W, Alshahrani M, Jaeschke R, Forel JM, Papazian L, Sevransky J, Meade MO. Alhazzani W, et al. Among authors: meade mo. Crit Care. 2013 Mar 11;17(2):R43. doi: 10.1186/cc12557. Crit Care. 2013. PMID: 23497608 Free PMC article. Review.
All trials assessed 48-hour infusions of cisatracurium besylate. Short-term infusion of cisatracurium besylate was associated with lower hospital mortality (RR, 0.72; 95% CI, 0.58 to 0.91; P=0.005; I2=0). ...Primary studies lacked protracted measurements of weakness. CONCL …
All trials assessed 48-hour infusions of cisatracurium besylate. Short-term infusion of cisatracurium besylate was associated with lo …
Recruitment maneuvers for acute lung injury: a systematic review.
Fan E, Wilcox ME, Brower RG, Stewart TE, Mehta S, Lapinsky SE, Meade MO, Ferguson ND. Fan E, et al. Among authors: meade mo. Am J Respir Crit Care Med. 2008 Dec 1;178(11):1156-63. doi: 10.1164/rccm.200802-335OC. Epub 2008 Sep 5. Am J Respir Crit Care Med. 2008. PMID: 18776154 Review.
Transient hypotension and desaturation during RMs is common but is self-limited without serious short-term sequelae. Given the uncertain benefit of transient oxygenation improvements in patients with ALI and the lack of information on their influence on clinical outcomes, …
Transient hypotension and desaturation during RMs is common but is self-limited without serious short-term sequelae. Given the uncert …
An evidence-based approach to acute respiratory distress syndrome.
Meade MO, Herridge MS. Meade MO, et al. Respir Care. 2001 Dec;46(12):1368-76; discussion 1376-9. Respir Care. 2001. PMID: 11728297 Review.
We searched MEDLINE and the Cumulative Index to Nursing and Allied Health for randomized trials evaluating lung-protective ventilation strategies, inhaled nitric oxide, prone positioning, and late-phase corticosteroids for managing these patients, and for additional literature re …
We searched MEDLINE and the Cumulative Index to Nursing and Allied Health for randomized trials evaluating lung-protective ventilation strat …
Long-term follow-up of survivors of acute lung injury: lack of effect of a ventilation strategy to prevent barotrauma.
Cooper AB, Ferguson ND, Hanly PJ, Meade MO, Kachura JR, Granton JT, Slutsky AS, Stewart TE. Cooper AB, et al. Among authors: meade mo. Crit Care Med. 1999 Dec;27(12):2616-21. doi: 10.1097/00003246-199912000-00002. Crit Care Med. 1999. PMID: 10628599 Clinical Trial.
OBJECTIVES: To determine the effect of a ventilation strategy to prevent barotrauma on long-term outcome in survivors of acute lung injury. DESIGN: Prospective blinded cohort analysis. ...We were unable to show that a limited ventilation strategy improves either long-te …
OBJECTIVES: To determine the effect of a ventilation strategy to prevent barotrauma on long-term outcome in survivors of acute lung i …