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Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT).
Paton NI, Stöhr W, Arenas-Pinto A, Clarke A, Williams I, Johnson M, Orkin C, Chen F, Lee V, Winston A, Gompels M, Fox J, Sanders K, Dunn DT; Protease Inhibitor monotherapy Versus Ongoing Triple therapy (PIVOT) Trial Team. Paton NI, et al. EClinicalMedicine. 2024 Feb 10;69:102457. doi: 10.1016/j.eclinm.2024.102457. eCollection 2024 Mar. EClinicalMedicine. 2024. PMID: 38361989 Free PMC article.
BACKGROUND: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy. METHODS: Eligible participants attending 43 UK treatment centres had a viral load (VL) below 50 copies …
BACKGROUND: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes f …
Longitudinal Evaluation of a Deprescribing Protocol in Skilled Nursing Facilities.
Morley CP, Schad LA, Cerio H, McNamara SE, Wojtowycz MA, Smith NH, Noviasky JA, Ulen KR, Townsend K, Amidon J, Brangman SA. Morley CP, et al. Among authors: mcnamara se. Sr Care Pharm. 2022 Oct 1;37(10):523-531. doi: 10.4140/TCP.n.2022.523. Sr Care Pharm. 2022. PMID: 36171671
Objective: To determine whether a deprescribing effort reduced several key classes of medications, and the overall number of medication classes per patient, among long-term residents of skilled nursing facilities (SNFs). Design: Retrospective, longitudinal pre/post evaluat …
Objective: To determine whether a deprescribing effort reduced several key classes of medications, and the overall number of medication clas …
Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome.
Nelson MT, Wolter DJ, Eng A, Weiss EJ, Vo AT, Brittnacher MJ, Hayden HS, Ravishankar S, Bautista G, Ratjen A, Blackledge M, McNamara S, Nay L, Majors C, Miller SI, Borenstein E, Simon RH, LiPuma JJ, Hoffman LR. Nelson MT, et al. Among authors: mcnamara s. Thorax. 2020 Sep;75(9):780-790. doi: 10.1136/thoraxjnl-2019-214187. Epub 2020 Jul 6. Thorax. 2020. PMID: 32631930 Free PMC article.
While the effects of inhaled tobramycin on P. aeruginosa abundance and lung function diminish with continued therapy, this maintenance treatment is known to improve long-term outcomes, underscoring how little is known about why antibiotics work in CF infections, what their …
While the effects of inhaled tobramycin on P. aeruginosa abundance and lung function diminish with continued therapy, this maintenance treat …
Discovery of a putative blood-based protein signature associated with response to ALK tyrosine kinase inhibition.
Couëtoux du Tertre M, Marques M, McNamara S, Gambaro K, Hoffert C, Tremblay L, Bouchard N, Diaconescu R, Blais N, Couture C, Pelsser V, Wang H, McIntosh L, Hindie V, Parent S, Cortes L, Breton YA, Pottiez G, Croteau P, Higenell V, Izzi L, Spatz A, Cohen V, Batist G, Agulnik J. Couëtoux du Tertre M, et al. Among authors: mcnamara s. Clin Proteomics. 2020 Feb 7;17:5. doi: 10.1186/s12014-020-9269-6. eCollection 2020. Clin Proteomics. 2020. PMID: 32055239 Free PMC article.
Several proteins were identified as differentially expressed between long-term responders and poor responders, including DPP4, KIT and LUM. ...Registered 22 January 2014, https://clinicaltrials.gov/ct2/show/NCT02041468?term=NCT02041468&rank=1....
Several proteins were identified as differentially expressed between long-term responders and poor responders, including DPP4, KIT an …
Can We Accurately Predict Cost Effectiveness Without Access to Overall Survival Data? The Case Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with Advanced Melanoma in England.
Lee D, Amadi A, Sabater J, Ellis J, Johnson H, Kotapati S, McNamara S, Walker A, Cooper M, Patterson K, Roskell N, Meng Y. Lee D, et al. Among authors: mcnamara s. Pharmacoecon Open. 2019 Mar;3(1):43-54. doi: 10.1007/s41669-018-0080-5. Pharmacoecon Open. 2019. PMID: 29790020 Free PMC article.
BACKGROUND: Nivolumab with ipilimumab (the Regimen) is the first immuno-oncology combination treatment to demonstrate long-term clinical benefit for advanced melanoma patients. We evaluated the cost effectiveness of the Regimen in this population, with and without the avai …
BACKGROUND: Nivolumab with ipilimumab (the Regimen) is the first immuno-oncology combination treatment to demonstrate long-term clini …
Do Safety Culture Scores in Nursing Homes Depend on Job Role and Ownership? Results from a National Survey.
Banaszak-Holl J, Reichert H, Todd Greene M, Mody L, Wald HL, Crnich C, McNamara SE, Meddings J. Banaszak-Holl J, et al. Among authors: mcnamara se. J Am Geriatr Soc. 2017 Oct;65(10):2244-2250. doi: 10.1111/jgs.15030. Epub 2017 Aug 28. J Am Geriatr Soc. 2017. PMID: 28846129 Free PMC article.
SETTING: Nursing homes participating in the national Agency for Healthcare Research and Quality Safety Program for Long-Term Care: Healthcare-Associated Infections/Catheter-Associated Urinary Tract Infections Project. ...
SETTING: Nursing homes participating in the national Agency for Healthcare Research and Quality Safety Program for Long-Term Care: He …
A National Implementation Project to Prevent Catheter-Associated Urinary Tract Infection in Nursing Home Residents.
Mody L, Greene MT, Meddings J, Krein SL, McNamara SE, Trautner BW, Ratz D, Stone ND, Min L, Schweon SJ, Rolle AJ, Olmsted RN, Burwen DR, Battles J, Edson B, Saint S. Mody L, et al. Among authors: mcnamara se. JAMA Intern Med. 2017 Aug 1;177(8):1154-1162. doi: 10.1001/jamainternmed.2017.1689. JAMA Intern Med. 2017. PMID: 28525923 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: A large-scale prospective implementation project was conducted in community-based nursing homes participating in the Agency for Healthcare Research and Quality Safety Program for Long-Term Care. Nursing homes across 48 states, Washington …
DESIGN, SETTING, AND PARTICIPANTS: A large-scale prospective implementation project was conducted in community-based nursing homes participa …
Comparing Catheter-Associated Urinary Tract Infection Prevention Programs Between Veterans Affairs Nursing Homes and Non-Veterans Affairs Nursing Homes.
Mody L, Greene MT, Saint S, Meddings J, Trautner BW, Wald HL, Crnich C, Banaszak-Holl J, McNamara SE, King BJ, Hogikyan R, Edson BS, Krein SL. Mody L, et al. Among authors: mcnamara se. Infect Control Hosp Epidemiol. 2017 Mar;38(3):287-293. doi: 10.1017/ice.2016.279. Epub 2016 Dec 5. Infect Control Hosp Epidemiol. 2017. PMID: 27917728 Free PMC article.
SETTING VA and non-VA nursing homes participating in the AHRQ Safety Program for Long-Term Care collaborative. METHODS Nursing homes provided baseline information about their infection prevention programs to assess strengths and gaps related to CAUTI prevention via a needs …
SETTING VA and non-VA nursing homes participating in the AHRQ Safety Program for Long-Term Care collaborative. METHODS Nursing homes …
Making infection prevention education interactive can enhance knowledge and improve outcomes: Results from the Targeted Infection Prevention (TIP) Study.
Koo E, McNamara S, Lansing B, Olmsted RN, Rye RA, Fitzgerald T, Mody L; Targeted Infection Prevention (TIP) Study Team, Ann Arbor, Michigan. Koo E, et al. Among authors: mcnamara s. Am J Infect Control. 2016 Nov 1;44(11):1241-1246. doi: 10.1016/j.ajic.2016.03.016. Epub 2016 Aug 20. Am J Infect Control. 2016. PMID: 27553671 Free PMC article.
Infection Prevention and Antimicrobial Stewardship Knowledge for Selected Infections Among Nursing Home Personnel.
Trautner BW, Greene MT, Krein SL, Wald HL, Saint S, Rolle AJ, McNamara S, Edson BS, Mody L. Trautner BW, et al. Among authors: mcnamara s. Infect Control Hosp Epidemiol. 2017 Jan;38(1):83-88. doi: 10.1017/ice.2016.228. Epub 2016 Oct 4. Infect Control Hosp Epidemiol. 2017. PMID: 27697086 Free PMC article.
SETTING Nursing homes across 14 states participating in the national "Agency for Healthcare Research and Quality Safety Program for Long-Term Care: Healthcare-Associated Infections/Catheter-Associated Urinary Tract Infection." ...
SETTING Nursing homes across 14 states participating in the national "Agency for Healthcare Research and Quality Safety Program for Long- …
18 results