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Health care costs of hospitalization of young children for respiratory syncytial virus infections: a population-based matched cohort study.
Thampi N, Knight BD, Thavorn K, Webster RJ, Lanctot K, Hawken S, McNally JD. Thampi N, et al. Among authors: mcnally jd. CMAJ Open. 2021 Oct 19;9(4):E948-E956. doi: 10.9778/cmajo.20200219. Print 2021 Oct-Dec. CMAJ Open. 2021. PMID: 34667075 Free PMC article.
Increased costs were associated with major comorbidities, but not extreme premature birth. The highest mean attributable cost per patient was in the presence of hemodynamically significant heart disease ($60 110, 95% CI $26 700-$93 060). ...INTERPRETATION: Although the gre …
Increased costs were associated with major comorbidities, but not extreme premature birth. The highest mean attributable cost per pat …
Antimicrobial Stewardship in Bronchiolitis: A Retrospective Cohort Study of Three PICUs in Canada.
Aljassim NA, Noël KC, Maratta C, Tam I, Almadani A, Papenburg J, Quach C, Thampi N, McNally JD, Dendukuri N, Lefebvre MA, Zavalkoff S, O'Donnell S, Jouvet P, Fontela PS. Aljassim NA, et al. Among authors: mcnally jd. Pediatr Crit Care Med. 2022 Mar 1;23(3):160-170. doi: 10.1097/PCC.0000000000002834. Pediatr Crit Care Med. 2022. PMID: 34560772
MEASUREMENTS AND MAIN RESULTS: We used regression models with an interaction term between site (PICU 1 and PICU 2) and season (1 and 2) as the primary analysis to determine the association between implementation of an antimicrobial stewardship program at PICU 1 and 1) the …
MEASUREMENTS AND MAIN RESULTS: We used regression models with an interaction term between site (PICU 1 and PICU 2) and season (1 and …
Influenza Vaccine Effectiveness Against All-Cause Mortality Following Laboratory-Confirmed Influenza in Older Adults, 2010-2011 to 2015-2016 Seasons in Ontario, Canada.
Chung H, Buchan SA, Campigotto A, Campitelli MA, Crowcroft NS, Dubey V, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Mubareka S, Murti M, Richardson DC, Rosella LC, Schwartz KL, Smieja M, Zahariadis G, Kwong JC. Chung H, et al. Among authors: mcnally jd. Clin Infect Dis. 2021 Sep 7;73(5):e1191-e1199. doi: 10.1093/cid/ciaa1862. Clin Infect Dis. 2021. PMID: 33354709 Free PMC article.
Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review.
Menon K, McNally JD, Zimmerman JJ, Agus MS, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Choong K. Menon K, et al. Among authors: mcnally jd. Pediatr Crit Care Med. 2017 Mar;18(3):e146-e154. doi: 10.1097/PCC.0000000000001078. Pediatr Crit Care Med. 2017. PMID: 28099233 Free PMC article. Review.
CONCLUSIONS: Our review found that use of mortality alone as a primary outcome in pediatric septic shock trials was associated with significant limitations and that long-term patient-centered outcomes were not used in this setting. Composite outcomes incorporating mortalit …
CONCLUSIONS: Our review found that use of mortality alone as a primary outcome in pediatric septic shock trials was associated with signific …
Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial.
McNally JD, O'Hearn K, Lawson ML, Maharajh G, Geier P, Weiler H, Redpath S, McIntyre L, Fergusson D, Menon K; Canadian Critical Care Trials Groups. McNally JD, et al. Trials. 2015 Sep 9;16:402. doi: 10.1186/s13063-015-0922-8. Trials. 2015. PMID: 26353829 Free PMC article. Clinical Trial.
The results will then be used to inform the design of a large international RCT exploring whether preoperative optimization of vitamin D status might improve short and long-term outcomes in this vulnerable population. TRIAL REGISTRATION: Clinicaltrials.gov Identifier--NCT0 …
The results will then be used to inform the design of a large international RCT exploring whether preoperative optimization of vitamin D sta …
Identification and characterization of a novel freezing inducible gene, li16, in the wood frog Rana sylvatica.
McNally JD, Wu SB, Sturgeon CM, Storey KB. McNally JD, et al. FASEB J. 2002 Jun;16(8):902-4. doi: 10.1096/fj.02-0017fje. Epub 2002 Apr 23. FASEB J. 2002. PMID: 12039874
Natural freeze tolerance includes both seasonal and freeze-induced molecular adaptations that control ice formation, deal with long-term ischemia, regulate cell volume changes, and protect macromolecules. ...
Natural freeze tolerance includes both seasonal and freeze-induced molecular adaptations that control ice formation, deal with long-term …