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Multipotent bone marrow cell-seeded polymeric composites drive long-term, definitive urinary bladder tissue regeneration.
Bury MI, Fuller NJ, Wang X, Chan YY, Sturm RM, Oh SS, Sofer LA, Arora HC, Sharma TT, Nolan BG, Feng W, Rabizadeh RR, Barac M, Edassery SS, Goedegebuure MM, Wang LW, Ganesh B, Halliday LC, Seniw ME, Edassery SL, Mahmud NB, Hofer MD, McKenna KE, Cheng EY, Ameer GA, Sharma AK. Bury MI, et al. Among authors: mckenna ke. PNAS Nexus. 2024 Jan 30;3(2):pgae038. doi: 10.1093/pnasnexus/pgae038. eCollection 2024 Feb. PNAS Nexus. 2024. PMID: 38344009 Free PMC article.
Considered the standard of care, BAE is fraught with numerous short- and long-term clinical complications. Previous clinical trials employing tissue engineering approaches for bladder tissue regeneration have also been unable to translate bench-top findings into clinical p …
Considered the standard of care, BAE is fraught with numerous short- and long-term clinical complications. Previous clinical trials e …
Adverse effects of topical photodynamic therapy: a consensus review and approach to management.
Ibbotson SH, Wong TH, Morton CA, Collier NJ, Haylett A, McKenna KE, Mallipeddi R, Moseley H, Rhodes LE, Seukeran DC, Ward KA, Mohd Mustapa MF, Exton LS. Ibbotson SH, et al. Among authors: mckenna ke. Br J Dermatol. 2019 Apr;180(4):715-729. doi: 10.1111/bjd.17131. Epub 2018 Oct 30. Br J Dermatol. 2019. PMID: 30183065 Review.
Other adverse effects include the risk of contact allergy to photosensitizer prodrugs, although this is rare but should be kept in mind, particularly for patients who have received multiple PDT treatments to larger areas. There are no other significant documented longer-term …
Other adverse effects include the risk of contact allergy to photosensitizer prodrugs, although this is rare but should be kept in mind, par …
Guidelines for topical photodynamic therapy: update.
Morton CA, McKenna KE, Rhodes LE; British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group. Morton CA, et al. Among authors: mckenna ke. Br J Dermatol. 2008 Dec;159(6):1245-66. doi: 10.1111/j.1365-2133.2008.08882.x. Epub 2008 Oct 13. Br J Dermatol. 2008. PMID: 18945319 Review.
Multicentre randomized controlled studies now demonstrate high efficacy of topical photodynamic therapy (PDT) for actinic keratoses, Bowen's disease (BD) and superficial basal cell carcinoma (BCC), and efficacy in thin nodular BCC, while confirming the superiority of cosmetic out …
Multicentre randomized controlled studies now demonstrate high efficacy of topical photodynamic therapy (PDT) for actinic keratoses, Bowen's …
Iatrogenic skin cancer: induction by psoralen/ultraviolet A and immunosuppression of organ transplant recipients.
McKenna KE. McKenna KE. Photodermatol Photoimmunol Photomed. 2004 Dec;20(6):289-96. doi: 10.1111/j.1600-0781.2004.00123.x. Photodermatol Photoimmunol Photomed. 2004. PMID: 15533236 Review.
Photochemotherapy (psoralen/UVA (PUVA)) is an efficient therapeutic tool for a wide range of skin diseases. Concern, however, exists regarding the long-term carcinogenic effects of this treatment modality and, as a consequence, is being used less frequently. ...
Photochemotherapy (psoralen/UVA (PUVA)) is an efficient therapeutic tool for a wide range of skin diseases. Concern, however, exists regardi …
Sildenafil causes a dose- and time-dependent downregulation of phosphodiesterase type 6 expression in the rat retina.
Gonzalez CM, Bervig T, Podlasek C, Huang CF, McKenna KE, McVary KT. Gonzalez CM, et al. Among authors: mckenna ke. Int J Impot Res. 1999 Sep;11 Suppl 1:S9-14. doi: 10.1038/sj.ijir.3900465. Int J Impot Res. 1999. PMID: 10554924
The safety profile of uninterrupted use of sildenafil has not been evaluated as it pertains to alteration of PDE type 6 in the retina. In the present study we investigated whether short- or long-term exposure to a variety of sildenafil doses affect the expression of an enz …
The safety profile of uninterrupted use of sildenafil has not been evaluated as it pertains to alteration of PDE type 6 in the retina. In th …
A role for 5-hydroxytryptamine in descending inhibition of spinal sexual reflexes.
Marson L, McKenna KE. Marson L, et al. Among authors: mckenna ke. Exp Brain Res. 1992;88(2):313-20. doi: 10.1007/BF02259106. Exp Brain Res. 1992. PMID: 1577105
Urethral stimulation, in the anesthetized male rat, elicited penile erections, ejaculation and rhythmic contractions of the perineal muscles, we have used the term coitus reflex to describe this response. Intrathecal injection of 5-HT (4-50 micrograms) abolished the coitus …
Urethral stimulation, in the anesthetized male rat, elicited penile erections, ejaculation and rhythmic contractions of the perineal muscles …