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1992 1
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2001 1
2002 1
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2011 1
2014 1
2015 2
2016 1
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2019 4
2020 3
2021 1
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2023 1
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28 results

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Page 1
Long-term Socioeconomic Outcomes Associated With Pediatric-Onset Multiple Sclerosis.
McKay KA, Friberg E, Razaz N, Alexanderson K, Hillert J. McKay KA, et al. JAMA Neurol. 2021 Apr 1;78(4):478-482. doi: 10.1001/jamaneurol.2020.5520. JAMA Neurol. 2021. PMID: 33616605 Free PMC article.
The general population reference cohort without multiple sclerosis (MS) (n = 4850) was randomly selected from the full Swedish population, matched 10:1 on age, sex, and country of birth. EXPOSURE: Pediatric-onset MS, diagnosed by a neurologist, with onset before 18 years o …
The general population reference cohort without multiple sclerosis (MS) (n = 4850) was randomly selected from the full Swedish population, m …
Long-term disability progression of pediatric-onset multiple sclerosis.
McKay KA, Hillert J, Manouchehrinia A. McKay KA, et al. Neurology. 2019 Jun 11;92(24):e2764-e2773. doi: 10.1212/WNL.0000000000007647. Epub 2019 May 15. Neurology. 2019. PMID: 31092624 Free PMC article.
OBJECTIVE: To evaluate long-term disability progression in pediatric-onset multiple sclerosis (POMS) and compare to adult-onset multiple sclerosis (AOMS). ...
OBJECTIVE: To evaluate long-term disability progression in pediatric-onset multiple sclerosis (POMS) and compare to adult-onset multi …
Impact of the COVID-19 pandemic: The perceptions of health professions educators.
Hays R, Jennings B, Gibbs T, Hunt J, McKay K. Hays R, et al. Among authors: mckay k. MedEdPublish (2016). 2020 Oct 6;9:142. doi: 10.15694/mep.2020.000142.2. eCollection 2020. MedEdPublish (2016). 2020. PMID: 38073853 Free PMC article.
Additional study is necessary to produce evidence for the teaching and assessment adaptations described. Some changes are likely to persist longer-term and may outlast the pandemic itself....
Additional study is necessary to produce evidence for the teaching and assessment adaptations described. Some changes are likely to persist …
Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG.
Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostásy K, Tenembaum S, Chitnis T; IPMSSG. Waubant E, et al. Neurology. 2019 May 28;92(22):e2538-e2549. doi: 10.1212/WNL.0000000000007572. Epub 2019 May 1. Neurology. 2019. PMID: 31043474 Free PMC article.
OBJECTIVE: The impetus for this consensus discussion was to recommend clinical trial designs that can deliver high-quality data for effective therapies for pediatric patients, in a reasonable timeframe, with a key focus on short- and long-term safety. METHODS: The Internat …
OBJECTIVE: The impetus for this consensus discussion was to recommend clinical trial designs that can deliver high-quality data for effectiv …
Factors associated with onset, relapses or progression in multiple sclerosis: A systematic review.
McKay KA, Jahanfar S, Duggan T, Tkachuk S, Tremlett H. McKay KA, et al. Neurotoxicology. 2017 Jul;61:189-212. doi: 10.1016/j.neuro.2016.03.020. Epub 2016 Apr 1. Neurotoxicology. 2017. PMID: 27045883 Review.
Relapse rates typically dropped during pregnancy, but there was no strong evidence to suggest that pregnancy itself altered the risk of MS or affected long-term progression. Emerging research with the greatest potential to impact public health was the suggestion that obesi …
Relapse rates typically dropped during pregnancy, but there was no strong evidence to suggest that pregnancy itself altered the risk of MS o …
ADHD, aggression, and antisocial behavior across the lifespan. Interactions with neurochemical and cognitive function.
McKay KE, Halperin JM. McKay KE, et al. Ann N Y Acad Sci. 2001 Jun;931:84-96. doi: 10.1111/j.1749-6632.2001.tb05774.x. Ann N Y Acad Sci. 2001. PMID: 11462758 Review.
An unremitting pattern of physical aggression appears of great import when predicting long-term outcome. However, a profile characterized by behavioral and cognitive impulsivity and emotional lability may indicate a greater likelihood of the progression to adult antisocial …
An unremitting pattern of physical aggression appears of great import when predicting long-term outcome. However, a profile character …
Finding Diagnostically Useful Patterns in Quantitative Phenotypic Data.
Aitken S, Firth HV, McRae J, Halachev M, Kini U, Parker MJ, Lees MM, Lachlan K, Sarkar A, Joss S, Splitt M, McKee S, Németh AH, Scott RH, Wright CF, Marsh JA, Hurles ME, FitzPatrick DR; DDD Study. Aitken S, et al. Am J Hum Genet. 2019 Nov 7;105(5):933-946. doi: 10.1016/j.ajhg.2019.09.015. Epub 2019 Oct 10. Am J Hum Genet. 2019. PMID: 31607427 Free PMC article.
Median Euclidean distances (mEuD) were employed as a simple measure of similarity of quantitative phenotypic data within sets of 10 individuals with plausibly causative de novo mutations (DNM) in 28 different developmental disorder genes. 13/28 (46.4%) showed significant similari …
Median Euclidean distances (mEuD) were employed as a simple measure of similarity of quantitative phenotypic data within sets of 10 individu …
Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice.
Gee LMV, Barron-Millar B, Leslie J, Richardson C, Zaki MYW, Luli S, Burgoyne RA, Cameron RIT, Smith GR, Brain JG, Innes B, Jopson L, Dyson JK, McKay KRC, Pechlivanis A, Holmes E, Berlinguer-Palmini R, Victorelli S, Mells GF, Sandford RN, Palmer J, Kirby JA, Kiourtis C, Mokochinski J, Hall Z, Bird TG, Borthwick LA, Morris CM, Hanson PS, Jurk D, Stoll EA, LeBeau FEN, Jones DEJ, Oakley F. Gee LMV, et al. Among authors: mckay krc. Am J Pathol. 2023 Jan;193(1):11-26. doi: 10.1016/j.ajpath.2022.09.005. Epub 2022 Oct 13. Am J Pathol. 2023. PMID: 36243043 Free article.
Herein, the study explored the neurocognitive symptom manifestations, and tested potential therapies, in BDL mice, and used human neuronal cell cultures to explore translatability to humans. BDL animals exhibited short-term memory loss and showed reduced astrocyte coverage …
Herein, the study explored the neurocognitive symptom manifestations, and tested potential therapies, in BDL mice, and used human neuronal c …
Association between brain volume and disability over time in multiple sclerosis.
Moridi T, Stawiarz L, McKay KA, Ineichen BV, Ouellette R, Ferreira D, Muehlboeck JS, Westman E, Kockum I, Olsson T, Piehl F, Hillert J, Manouchehrinia A, Granberg T. Moridi T, et al. Among authors: mckay ka. Mult Scler J Exp Transl Clin. 2022 Dec 18;8(4):20552173221144230. doi: 10.1177/20552173221144230. eCollection 2022 Oct-Dec. Mult Scler J Exp Transl Clin. 2022. PMID: 36570871 Free PMC article.
OBJECTIVES: To investigate which brain and lesion volume metrics show the strongest long-term associations with the expanded disability status scale (EDSS), SDMT, and MSIS-29, and whether MRI-clinical associations vary with age. ...Grey matter volume fractions are stronger …
OBJECTIVES: To investigate which brain and lesion volume metrics show the strongest long-term associations with the expanded disabili …
28 results