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Should I Take Aspirin? (SITA): RCT of a decision aid for cancer chemoprevention.
Onwuka SR, Boyd L, Wijesuriya R, Broun K, Marker J, Shub M, McIntosh JG, Macrae F, Chondros P, Saya S, Novy K, Jenkins MA, Walter FM, Trevena L, Martinez Gutierrez J, Fishman G, Emery J. Onwuka SR, et al. Among authors: mcintosh jg. Br J Gen Pract. 2024 Mar 25:BJGP.2023.0385. doi: 10.3399/BJGP.2023.0385. Online ahead of print. Br J Gen Pract. 2024. PMID: 38527793
Conclusion The decision aid improved informed decision-making; but has little effect on long-term regular use of aspirin to reduce CRC risk....
Conclusion The decision aid improved informed decision-making; but has little effect on long-term regular use of aspirin to reduce CR …
αO-Conotoxin GeXIVA[1,2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model.
Wang H, Li X, Qiao Y, Wang M, Wang W, McIntosh JM, Zhangsun D, Luo S. Wang H, et al. Among authors: mcintosh jm. Mar Drugs. 2024 Jan 19;22(1):49. doi: 10.3390/md22010049. Mar Drugs. 2024. PMID: 38276651 Free PMC article.
Here, we analyzed the preventive effect of GeXIVA[1,2] on neuropathic pain in the long-term oxaliplatin injection-induced CIPN model. At the end of treatment, lumbar (L4-L6) spinal cord was extracted, and RNA sequencing and bioinformatic analysis were performed to investig …
Here, we analyzed the preventive effect of GeXIVA[1,2] on neuropathic pain in the long-term oxaliplatin injection-induced CIPN model. …
SMARTERscreen protocol: a three-arm cluster randomised controlled trial of patient SMS messaging in general practice to increase participation in the Australian National Bowel Cancer Screening Program.
McIntosh JG, Emery JD, Wood A, Chondros P, Goodwin BC, Trevena J, Wilson C, Chang S, Hocking J, Campbell T, Macrae F, Milley K, Lew JB, Nightingale C, Dixon I, Castelli M, Lee N, Innes L, Jolley T, Fletcher S, Buchanan L, Doncovio S, Broun K, Austin G, Jiang J, Jenkins MA. McIntosh JG, et al. Trials. 2023 Nov 13;24(1):723. doi: 10.1186/s13063-023-07756-5. Trials. 2023. PMID: 37957680 Free PMC article.
Findings will be incorporated into the Policy1-Bowel microsimulation model to estimate the long-term health benefits and cost-effectiveness of the interventions. ...
Findings will be incorporated into the Policy1-Bowel microsimulation model to estimate the long-term health benefits and cost-effecti …
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.
C-MORE/PHOSP-COVID Collaborative Group. C-MORE/PHOSP-COVID Collaborative Group. Lancet Respir Med. 2023 Nov;11(11):1003-1019. doi: 10.1016/S2213-2600(23)00262-X. Epub 2023 Sep 22. Lancet Respir Med. 2023. PMID: 37748493 Free PMC article.
INTERPRETATION: After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeu …
INTERPRETATION: After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings e …
Adeno-associated virus gene therapy prevents progression of kidney disease in genetic models of nephrotic syndrome.
Ding WY, Kuzmuk V, Hunter S, Lay A, Hayes B, Beesley M, Rollason R, Hurcombe JA, Barrington F, Masson C, Cathery W, May C, Tuffin J, Roberts T, Mollet G, Chu CJ, McIntosh J, Coward RJ, Antignac C, Nathwani A, Welsh GI, Saleem MA. Ding WY, et al. Among authors: mcintosh j. Sci Transl Med. 2023 Aug 9;15(708):eabc8226. doi: 10.1126/scitranslmed.abc8226. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556557
A prophylactic approach of AAV 2/9 gene transfer before induction of disease in conditional knockout mice demonstrated improvements in albuminuria, plasma creatinine, plasma urea, plasma cholesterol, histological changes, and long-term survival. A therapeutic approach of A …
A prophylactic approach of AAV 2/9 gene transfer before induction of disease in conditional knockout mice demonstrated improvements in album …
Smartphone-Based Video Antenatal Preterm Birth Education: The Preemie Prep for Parents Randomized Clinical Trial.
Flynn KE, McDonnell SM, Brazauskas R, Ahamed SI, McIntosh JJ, Pitt MB, Pizur-Barnekow K, Kim UO, Kruper A, Leuthner SR, Basir MA. Flynn KE, et al. Among authors: mcintosh jj. JAMA Pediatr. 2023 Jul 31;177(9):921-9. doi: 10.1001/jamapediatrics.2023.1586. Online ahead of print. JAMA Pediatr. 2023. PMID: 37523163 Free PMC article.
IMPORTANCE: Preterm birth is a leading cause of infant mortality and child morbidity. Preterm birth is not always unexpected, yet standard prenatal care does not offer anticipatory education to parents at risk of delivering preterm, which leaves parents unprepared t …
IMPORTANCE: Preterm birth is a leading cause of infant mortality and child morbidity. Preterm birth is not always unexpected, …
Life course psychosocial precursors of parent mental health resilience during the COVID-19 pandemic: A three-decade prospective cohort study.
Letcher P, Greenwood CJ, Macdonald JA, McIntosh J, Spry EA, Hutchinson D, O'Connor M, Biden EJ, Painter FL, Olsson CM, Cleary J, Thomson KC, Olsson CA. Letcher P, et al. Among authors: mcintosh j. J Affect Disord. 2023 Aug 15;335:473-483. doi: 10.1016/j.jad.2023.05.039. Epub 2023 May 17. J Affect Disord. 2023. PMID: 37207948 Free PMC article.
DISCUSSION: Results identified psychosocial indicators across the early life course that, if replicated, could constitute targets for long-term investment to maximise mental health resilience during future pandemics and crises....
DISCUSSION: Results identified psychosocial indicators across the early life course that, if replicated, could constitute targets for long- …
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study.
Jackson C, Stewart ID, Plekhanova T, Cunningham PS, Hazel AL, Al-Sheklly B, Aul R, Bolton CE, Chalder T, Chalmers JD, Chaudhuri N, Docherty AB, Donaldson G, Edwardson CL, Elneima O, Greening NJ, Hanley NA, Harris VC, Harrison EM, Ho LP, Houchen-Wolloff L, Howard LS, Jolley CJ, Jones MG, Leavy OC, Lewis KE, Lone NI, Marks M, McAuley HJC, McNarry MA, Patel BV, Piper-Hanley K, Poinasamy K, Raman B, Richardson M, Rivera-Ortega P, Rowland-Jones SL, Rowlands AV, Saunders RM, Scott JT, Sereno M, Shah AM, Shikotra A, Singapuri A, Stanel SC, Thorpe M, Wootton DG, Yates T, Gisli Jenkins R, Singh SJ, Man WD, Brightling CE, Wain LV, Porter JC, Thompson AAR, Horsley A, Molyneaux PL, Evans RA, Jones SE, Rutter MK, Blaikley JF; PHOSP-COVID Study Collaborative Group. Jackson C, et al. Lancet Respir Med. 2023 Aug;11(8):673-684. doi: 10.1016/S2213-2600(23)00124-8. Epub 2023 Apr 15. Lancet Respir Med. 2023. PMID: 37072018 Free PMC article.
Bridging pre-surgical endocrine therapy for breast cancer during the COVID-19 pandemic: outcomes from the B-MaP-C study.
Dave RV, Elsberger B, Taxiarchi VP, Gandhi A, Kirwan CC, Kim B, Camacho EM, Coles CE, Copson E, Courtney A, Horgan K, Fairbrother P, Holcombe C, Kirkham JJ, Leff DR, McIntosh SA, O'Connell R, Pardo R, Potter S, Rattay T, Sharma N, Vidya R, Cutress RI; B-MaP-C study collaborative. Dave RV, et al. Breast Cancer Res Treat. 2023 Jun;199(2):265-279. doi: 10.1007/s10549-023-06893-4. Epub 2023 Apr 3. Breast Cancer Res Treat. 2023. PMID: 37010651 Free PMC article.
BrET was found to be tolerable and safe. The data support short-term ( 3 months) usage of pre-operative endocrine therapy. Longer-term use should be investigated in future trials....
BrET was found to be tolerable and safe. The data support short-term ( 3 months) usage of pre-operative endocrine therapy. Longer- …
Prevalence of physical frailty, including risk factors, up to 1 year after hospitalisation for COVID-19 in the UK: a multicentre, longitudinal cohort study.
McAuley HJC, Evans RA, Bolton CE, Brightling CE, Chalmers JD, Docherty AB, Elneima O, Greenhaff PL, Gupta A, Harris VC, Harrison EM, Ho LP, Horsley A, Houchen-Wolloff L, Jolley CJ, Leavy OC, Lone NI, Man WD, Marks M, Parekh D, Poinasamy K, Quint JK, Raman B, Richardson M, Saunders RM, Sereno M, Shikotra A, Singapuri A, Singh SJ, Steiner M, Tan AL, Wain LV, Welch C, Whitney J, Witham MD, Lord J, Greening NJ; PHOSP-COVID Study Collaborative Group. McAuley HJC, et al. EClinicalMedicine. 2023 Mar 11;57:101896. doi: 10.1016/j.eclinm.2023.101896. eCollection 2023 Mar. EClinicalMedicine. 2023. PMID: 36936404 Free PMC article.
BACKGROUND: The scale of COVID-19 and its well documented long-term sequelae support a need to understand long-term outcomes including frailty. ...
BACKGROUND: The scale of COVID-19 and its well documented long-term sequelae support a need to understand long-term outcomes i …
79 results