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Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer's disease in a mouse model of Aβ amyloidosis.
Sci Adv. 2021 Nov 5;7(45):eabe3954. doi: 10.1126/sciadv.abe3954. Epub 2021 Nov 3.
Sci Adv. 2021.
PMID: 34731000
Free PMC article.
We demonstrate that the deletion of Abi3 locus significantly increases amyloid beta (Abeta) accumulation and decreases microglia clustering around the plaques. Furthermore, long-term potentiation is impaired in 5XFAD;Abi3 knockout ("Abi3(/)") mice. ...
We demonstrate that the deletion of Abi3 locus significantly increases amyloid beta (Abeta) accumulation and decreases microglia clustering …
Long term renal prognosis of Henoch-Schonlein purpura in an unselected childhood population.
Stewart M, Savage JM, Bell B, McCord B.
Stewart M, et al. Among authors: mccord b.
Eur J Pediatr. 1988 Feb;147(2):113-5. doi: 10.1007/BF00442205.
Eur J Pediatr. 1988.
PMID: 3366130
The overall prognosis in this unselected population is therefore good with a mortality less than 1% overall and low long term morbidity of 1.1%. This study indicates a more optimistic outcome in this condition than the majority of published estimates based on more selected …
The overall prognosis in this unselected population is therefore good with a mortality less than 1% overall and low long term morbidi …
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