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Effect of a Hybrid Closed-Loop System on Glycemic and Psychosocial Outcomes in Children and Adolescents With Type 1 Diabetes: A Randomized Clinical Trial.
JAMA Pediatr. 2021 Dec 1;175(12):1227-1235. doi: 10.1001/jamapediatrics.2021.3965.
JAMA Pediatr. 2021.
PMID: 34633418
Free PMC article.
Clinical Trial.
IMPORTANCE: Hybrid closed-loop (HCL) therapy has improved glycemic control in children and adolescents with type 1 diabetes; however, the efficacy of HCL on glycemic and psychosocial outcomes has not yet been established in a long-term randomized clinical trial. OBJECTIVE: …
IMPORTANCE: Hybrid closed-loop (HCL) therapy has improved glycemic control in children and adolescents with type 1 diabetes; however, the ef …
Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study.
Paldus B, Lee MH, Jones HM, McAuley SA, Horsburgh JC, Roem KL, Ward GM, MacIsaac RJ, Cohen N, Colman PG, Jenkins AJ, O'Neal DN.
Paldus B, et al. Among authors: mcauley sa.
Diabetes Technol Ther. 2019 Jan;21(1):56-58. doi: 10.1089/dia.2018.0279.
Diabetes Technol Ther. 2019.
PMID: 30620641
Clinical Trial.
Relative to s-HCL, e-HCL use significantly decreases CL exits and alerts, and tended to improve glycemia without compromising safety, despite multiple food and exercise challenges during the study. Longer term studies at home are merited....
Relative to s-HCL, e-HCL use significantly decreases CL exits and alerts, and tended to improve glycemia without compromising safety, despit …
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Effect of 6 months hybrid closed-loop insulin delivery in young people with type 1 diabetes: a randomised controlled trial protocol.
de Bock M, McAuley SA, Abraham MB, Smith G, Nicholas J, Ambler GR, Cameron FJ, Fairchild JM, King BR, Geelhoed EA, Davis EA, O'Neal DN, Jones TW; Australian JDRF Closed-Loop Research Group.
de Bock M, et al. Among authors: mcauley sa.
BMJ Open. 2018 Aug 13;8(8):e020275. doi: 10.1136/bmjopen-2017-020275.
BMJ Open. 2018.
PMID: 30104309
Free PMC article.
Clinical Trial.
This study aims to establish the safety and efficacy of a hybrid closed-loop (HCL) system in a long-term outpatient trial in people with T1D aged 12 -<25 years of age, and compare outcomes with standard therapy for T1D as used in the contemporary community. ...
This study aims to establish the safety and efficacy of a hybrid closed-loop (HCL) system in a long-term outpatient trial in people w …
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Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: a randomised controlled trial protocol.
McAuley SA, de Bock MI, Sundararajan V, Lee MH, Paldus B, Ambler GR, Bach LA, Burt MG, Cameron FJ, Clarke PM, Cohen ND, Colman PG, Davis EA, Fairchild JM, Hendrieckx C, Holmes-Walker DJ, Horsburgh JC, Jenkins AJ, Kaye J, Keech AC, King BR, Kumareswaran K, MacIsaac RJ, McCallum RW, Nicholas JA, Sims C, Speight J, Stranks SN, Trawley S, Ward GM, Vogrin S, Jones TW, O'Neal DN.
McAuley SA, et al.
BMJ Open. 2018 Jun 9;8(6):e020274. doi: 10.1136/bmjopen-2017-020274.
BMJ Open. 2018.
PMID: 29886443
Free PMC article.
Automated insulin delivery via closed-loop systems has improved glucose control in short-term studies. The objective of the present study is to determine the effectiveness of 6 months' closed-loop compared with manually determined insulin dosing on time-in-target glucose r …
Automated insulin delivery via closed-loop systems has improved glucose control in short-term studies. The objective of the present s …
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Thirty-years of screening for cystic fibrosis in East Anglia.
Calvin J, Hogg SL, McShane D, McAuley SA, Iles R, Ross-Russell R, MacLean FM, Heeley ME, Heeley AF; Norfolk, Suffolk and Cambridgeshire Paediatric Cystic Fibrosis Network.
Calvin J, et al. Among authors: mcauley sa.
Arch Dis Child. 2012 Dec;97(12):1043-7. doi: 10.1136/archdischild-2012-301968. Epub 2012 Oct 16.
Arch Dis Child. 2012.
PMID: 23076339
The PPVs increased to 82.2% and 98.2% respectively if only well, term babies were considered. The main factor to account for this improvement in PPV has probably been the incorporation of DNA analysis in the second tier testing. ...
The PPVs increased to 82.2% and 98.2% respectively if only well, term babies were considered. The main factor to account for this imp …
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